Inflammation Clinical Trial
Official title:
The Comprehensive Analysis of Health Records, TCM Constitution, Biomarker, and Whole-genome Sequencing Among Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan
The comprehensive analysis of health records, TCM constitution, biomarker, and whole-genome sequencing among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease in Taiwan: an integrated analysis between Taiwan Biobank and Sjögren's syndrome Database
Status | Not yet recruiting |
Enrollment | 100000 |
Est. completion date | December 31, 2027 |
Est. primary completion date | December 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 75 Years |
Eligibility | Sjögren's syndrome Inclusion Criteria: 1. aged between 20 and 75 years 2. fulfilled the 2002 American-European Consensus Criteria for SS (AECG) Exclusion Criteria: NA Dry eye syndrome Inclusion Criteria: 1. aged between 20 and 75 years 2. Schirmer's test less than 10 mm/5 min Exclusion Criteria: NA Inflammation disease Inclusion Criteria: 1. aged between 20 and 75 years 2. Disease diagnosed with Inflammation Exclusion Criteria: NA |
Country | Name | City | State |
---|---|---|---|
Taiwan | Ching-Mao Chang | Taipei | Taiwan (r.o.c.) |
Lead Sponsor | Collaborator |
---|---|
Taipei Veterans General Hospital, Taiwan |
Taiwan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Immunity-related gene expression | To evaluate the immunity-related gene expression for Dry eye syndrome, Sjögren's syndrome and healthy control.
DNA exome combine the GATK (Genome Analysis Toolkit) is a tool for detecting the ratio of immunity-related gene expression. |
Five year | |
Primary | TCM pattern | To evaluate the difference of TCM pattern between Dry eye syndrome, Sjögren's syndrome and healthy control.
TCM pattern is a tool for detecting the constitution. |
Five year |
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