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Healthy Control clinical trials

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NCT ID: NCT05683184 Recruiting - Opioid Use Disorder Clinical Trials

OMAR Opioid Use Disorder

Start date: March 10, 2023
Phase: Phase 1
Study type: Interventional

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

NCT ID: NCT04895826 Recruiting - Back Pain Clinical Trials

Computer-vision Aided Community Back Pain Physiotherapy Services

CV
Start date: April 1, 2021
Phase:
Study type: Observational

Back pain affects one-third of the UK population every year with a huge impact on the health service and economy. The aim of this study is to test the validity of a computer-vision (CV) technology that uses cameras on phones/tablets/webcams to assess a person's movement and function with the ultimate goal to use the CV system to screen for back pain conditions. Participants with and without back pain will be included in the study and they will be asked to perform standard functional movements that would be used for a physiotherapy assessment for a back condition. The participants will also perform these movements in front of a camera for video recordings to be analysed by the CV system. The measurements by the CV system will be compared to the measurements by the physiotherapist. Additionally, participants will perform and record videos of the same set of movements at home to test the feasibility of the CV system in a home environment.

NCT ID: NCT04421079 Recruiting - Healthy Control Clinical Trials

Metabolism of Bioactive Dietary Polyphenol Preparation (BDPP)

Start date: January 19, 2021
Phase: Phase 1
Study type: Interventional

This study will characterize the clinical pharmacology of a select bioactive polyphenol-rich preparation (Bioactive Dietary Polyphenol Preparation, BDPP) comprised of a select Concord grape juice (CGJ), a select grape seed polyphenol extract (GSPE) and trans-resveratrol (RSV).

NCT ID: NCT04393558 Active, not recruiting - COVID-19 Clinical Trials

Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms

Start date: April 20, 2020
Phase:
Study type: Observational

1. Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. 2. Create algorithms to monitor and track changes to COVID19-like signs and symptoms for developing a better care and isolation strategies for COVID-19 pandemic.

NCT ID: NCT04036669 Completed - Clinical trials for Rheumatoid Arthritis

Adipokines as Predictors of Foot Function, Pain, and Disability in Patients With Rheumatoid Arthritis

Start date: February 20, 2014
Phase:
Study type: Observational

Significant increase in the levels of serum adiponectin, ADA, and hsCRP was reported in all RA patients compared to controls. Compared to patients with early RA, the increase in these markers significantly correlated with disease activity (DAS-ESR), lower f-BMD, radiographic scoring, pain, FFI, and functional limitations in patients with established RA. Adiponectin showed a negative correlation with serum levels of both ADA and hsCRP. By using ROC curve analysis, optimal cut-off values of adiponectin (28.8 µg/ml), ADA (27.3 IU/L), and hsCRP (1.6 mg/L) could be used to estimate early RA in 45 % of the patients. Similarly, using cut-off values of adiponectin (32.8 µg/ml), ADA (26.1 IU/L ml), and hsCRP (2.5 mg/L), established RA could be predicted in 55 % of patients with 98-99% accuracy.

NCT ID: NCT03938207 Not yet recruiting - Inflammation Clinical Trials

Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank

Start date: October 1, 2022
Phase:
Study type: Observational

The comprehensive analysis of health records, TCM constitution, biomarker, and whole-genome sequencing among dry eye syndrome, healthy control, Sjögren's syndrome and other inflammation disease in Taiwan: an integrated analysis between Taiwan Biobank and Sjögren's syndrome Database

NCT ID: NCT03914599 Completed - Clinical trials for Neurological Disorder

Protective Genetic Factors Against Neurological Diseases

Start date: April 15, 2019
Phase:
Study type: Observational [Patient Registry]

NIH Precision Medicine Initiative, started in May 2018, will enroll one million people through an online portal. It hopes to identify genetic variants affecting a variety of human phenotypic outcomes. A giant set of data like this may enable an association of genetic variants with a certain phenotype. However, the association is often compromised due to the collection of phenotypic data that is not well controlled or standardized creating "noisy" data. These phenotypic "noises" can be largely eliminated in clinical studies with stringent criteria and standardization of outcome measurements. In this study, by looking mainly at genetic information and nerve conduction speed, we hope to eliminate the extra "noises" in the data set. Eliminating the extra "noises" should allow us to be able to determine if there are genetic differences between neurological disorders and healthy controls, and if these genetic differences can be attributed to the speed of the nerve conduction.

NCT ID: NCT03443193 Completed - Clinical trials for Coronary Heart Disease

Periodization of Exercise Training in Patients With Coronary Heart Disease.

PERIOD
Start date: December 16, 2015
Phase: N/A
Study type: Interventional

The research project includes two components that assess exercise physiology parameters, cerebrovascular reserve, cognitive functions and cardiac function in coronary heart disease patients at rest, during an acute exercise, and after two different periodized training programs.

NCT ID: NCT03049709 Completed - Diabetes Mellitus Clinical Trials

Non-invasive Validation of Non-invasive Central Blood Pressure Measurements Using Oscillometric Pulse Wave Analysis

MEASURE-cBP2
Start date: May 1, 2015
Phase: N/A
Study type: Observational

There is growing evidence that central blood pressure is a better predictor of hypertensive end-organ damage and cardiovascular outcome than routine brachial readings. The investigators aimed to evaluate the accuracy of a novel device for the non-invasive determination of central blood pressure based on automated oscillometric radial pulse wave analysis.

NCT ID: NCT02995200 Completed - Healthy Control Clinical Trials

Quantification of Upper Extremity Use and Effects of Feedback in the Home Setting

UnSumRes2015
Start date: February 2015
Phase: N/A
Study type: Interventional

A pilot study, the purpose of which is to use accelerometers to quantify UE use (1 and two hand use) in healthy controls and people post-stroke from which the investigators will develop use-based feedback to improve recovery in the home setting. The objectives of this pilot study are to: i.) determine the feasibility of using accelerometers to quantify amount of UE use in the home setting in healthy individuals and individuals chronic post-stroke, ii.) quantify and compare the unilateral activity of the weaker (paretic) versus stronger (non-paretic) UEs, iii.) quantify and compare amount of UE use in healthy controls to that of people chronic post-stroke (side matched unimanual use for each arm and bilateral use) in the home, and iv.) assess the effect of a few sessions of in-home accelerometer used-based feedback on unilateral and bilateral UE use. v.) assess kinematic, kinetic, and EMG data during UE movements bilaterally and between healthy controls and subjects post-chronic stroke pre and post feedback (for the people after stroke).