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Inflammation clinical trials

View clinical trials related to Inflammation.

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NCT ID: NCT05718453 Completed - Copd Clinical Trials

Assessment of Trace Elements, Systemic Inflammation and Electrolytes

Start date: June 1, 2019
Phase: Phase 1
Study type: Interventional

COPD is one of the most common causes of health problems worldwide. It is a disease that is associated with several systemic features that affect its morbidity and mortality.

NCT ID: NCT05698420 Completed - Depressive Disorder Clinical Trials

Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients

Start date: March 1, 2020
Phase:
Study type: Observational

In this study, the investigators aimed to observe the effects of medium cut-off dialysis filters and high-flux dialysis filters on malnutrition inflammation score, uremic itching, restless leg syndrome, anemia, and ESA treatment, which are prominent complications in hemodialysis, and routine follow-up parameters.

NCT ID: NCT05698381 Completed - Depression Clinical Trials

Daily Vinegar Ingestion and Metabolic Health

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if vinegar ingestion promotes beneficial changes to metabolic health parameters in healthy, overweight adults.

NCT ID: NCT05689749 Completed - Inflammation Clinical Trials

Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren Syndrome

SMI
Start date: April 1, 2021
Phase:
Study type: Observational

A prospective study will be conducted to evaluate inflammatory activity in lacrimal glands due to Sjögren's syndrome on Superb Microvascular Imaging (SMI), gray scale ultrasound (US), color Doppler US and Power Doppler US.

NCT ID: NCT05682222 Completed - Clinical trials for KLH and Imiquimod Induced Skin Inflammation in Healthy Volunteers

Evaluation of the Immunopharmacology of EDP1815 and EDP2939

Start date: June 27, 2022
Phase: Phase 1
Study type: Interventional

A single-center, randomized, double-blind, placebo-controlled, multiple dose platform trial.

NCT ID: NCT05680441 Completed - Periodontitis Clinical Trials

GCF Annexin-A1, Carbonic Anhydrase-1, and Elongation Factor-1 Gamma Levels in Periodontitis

Start date: September 1, 2022
Phase:
Study type: Observational

The study aimed to investigate gingival crevicular fluid (GCF) levels of possible novel biomarkers Annexin-A1 (ANX A1), Carbonic anhydrase- 1 (CA I), and Elongation Factor-1 Gamma (EF1-Ɣ) in health along with different periodontal diseases. In total, 80 systemically healthy individuals were included in this study; 20 with periodontitis stage 3 grade B , 20 with periodontitis stage 3 grade C (P-Stage III/C), 19 with gingivitis, and 21 with clinically healthy periodontium. Probing depth, clinical attachment level, plaque index, and papillary bleeding index were recorded. GCF ANX A1, CA I and EF1-Ɣ levels were analyzed by enzyme-linked immunosorbent assay (ELISA). Receiver operating characteristics curve was used for estimating the under the curve.

NCT ID: NCT05679310 Completed - Inflammation Clinical Trials

Innovative Biotechnological Production of Antioxidant Products

Antiox-Plus
Start date: February 10, 2022
Phase: N/A
Study type: Interventional

Several natural compounds have been explored as immune-boosting, antioxidant, and anti-inflammatory dietary supplements. Amongst them, hydroxytyrosol a natural antioxidant found in olive products, and endemic medicinal plants have attracted the scientific's community and industry's interest. The safety and biological activity of a standardised supplement containing 10 mg of hydroxytyrosol synthesized using genetically modified Escherichia coli strains and equal amounts (8.33 μL) of essential oils from oregano vulgaris, sage officinalis and crithmum maritimum in an open-label, single-arm, prospective clinical study were studied. The supplement capsules were given to 12 healthy subjects, aged 26-52, once a day for 8 weeks.

NCT ID: NCT05675163 Completed - Inflammation Clinical Trials

Antioxidant and Immune Effects of Vitamin K2

ProteK2t
Start date: November 15, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to obtain insight into a dose-dependent effect of vitamin K2 on oxidative stress and specific markers of the immune system.

NCT ID: NCT05674708 Completed - Inflammation Clinical Trials

Fat Quality and Postprandial Inflammation

PI:fat
Start date: February 7, 2023
Phase: N/A
Study type: Interventional

This aim of this randomized controlled postprandial study is to compare the effects of four different far sources (butter, coconut, corn oil and flax seed oil) on postprandial inflammation and metabolic response. The main questions it aims to answer are: 1. What is the impact of different dietary sources of saturated and polyunsaturated fatty acids on postprandial inflammation? 2. Is the impact of different dietary sources of saturated and polyunsaturated fatty acids on postprandial inflammation mediated by glucose or blood lipids? 3. Can postprandial inflammatory or metabolic response be predicted by individual factors at baseline? Participants will consume four meals, identical except for the fat source, in random order and sampled for blood and urine for up to 6 hours.

NCT ID: NCT05666622 Completed - Periodontitis Clinical Trials

DNI Values After Periodontal Treatment

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease. Blood samples were taken for the examination of DNI, white blood cells (WBC), immature granulocytes (IG), procalcitonin, C-reactive protein (CRP), lymphocyte count and neutrophil count. For the patients with periodontitis, blood sample assays were repeated 3 months after NSPT.