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Infertility clinical trials

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NCT ID: NCT02013973 Completed - Infertility Clinical Trials

Predictive Value of AMH in IVF; a Prospective RCT

AMH
Start date: March 2013
Phase: N/A
Study type: Interventional

The primary aim of this trial is to compare two groups of women undergoing IVF (IVF=in vitro fertilisation ) treatment, to investigate if assessment of AMH (AMH=Anti-Müllerian hormone ), in addition to assessment of maternal age, AFC (AFC=antral follicle count ) and BMI (BMI=body mass index ) gives a more optimal COH (COH=controlled ovarian stimulation than does assessment of only age, AFC and BMI, measured as number of patients obtaining 5-12 oocytes during COH.

NCT ID: NCT02009891 Completed - Infertility Clinical Trials

Use of Predictive Model to Assist Patients Having an Embryo Transfer After IVF

Start date: June 2012
Phase: N/A
Study type: Observational

To determine in women undergoing IVF who are at high risk of multiple births (>35%), as calculated by the application of a predictive model - IVFsingleTM, if single embryo transfer will lead to both comparable clinical pregnancy rate (CPR) and other secondary outcomes such as live birth rate (LBR) and cumulative live birth rate (cLBR) in comparison to DET while reducing the incidence of multiple births (a secondary outcome measure).

NCT ID: NCT02008240 Completed - Infertility Clinical Trials

Salpingectomy Versus Aspiration of Hydrosalpingeal Fluid Prior to IVF-ET

Start date: August 2011
Phase: Phase 2
Study type: Interventional

The aim of this randomized controlled trial is to compare the efficacy of ultrasound guided aspiration of hydrosalpingeal fluid with salpingectomy in the management patients with ultrasound visible hydrosalpinges undergoing IVF-ET.

NCT ID: NCT02006446 Completed - Male Infertility Clinical Trials

Relationship Between Sperm Head Vacuoles and Sperm DNA Alterations in Infertile Men

VATES
Start date: December 2013
Phase: N/A
Study type: Observational [Patient Registry]

In men presenting sperm alterations, the selection of genetically undamaged spermatozoa need to be improved in order to increase the success of assisted reproduction treatments. The aim of this study is to determine whether the presence of sperm head vacuoles is associated with sperm DNA alterations.

NCT ID: NCT02006316 Completed - Varicocele Clinical Trials

Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters for Causes Other Than Infertility

Start date: January 2000
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the semen parameter in patients unrelated with infertility.

NCT ID: NCT02005263 Completed - Infertility Clinical Trials

Hysteroscopic Assessment of Fallopian Tubal Patency

Start date: December 2013
Phase: N/A
Study type: Interventional

Disease of the fallopian tubes is one of the most common reasons for infertility. The most common test, a hysterosalpingogram, tends to be painful,inconvenient, and frequently misses concurrent uterine disease. We propose using a less painful technique (through modified office hysteroscopy) for tubal assessment that can be performed in the office rather than hospital radiology and that uses gold standard technology for identifying coexisting uterine conditions.

NCT ID: NCT02003157 Completed - Infertility Clinical Trials

Efficacy of Hypnosis During Embryo Transfer Procedure on Clinical Pregnancy Rate for Patients Undergoing Assisted Reproductive Technology IVF or ICSI

HYPNOART
Start date: June 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the clinical benefits that can be expected by the Embryo transfert procedure with hypnosis to the usual embryo transfer procedure

NCT ID: NCT01999959 Completed - Infertility Clinical Trials

Effect of Pertubation on Pregnancy Rates Before Intrauterine Insemination Treatment

Start date: January 2010
Phase: Phase 2
Study type: Interventional

To demonstrate a possible beneficial impact of pertubation we designed a randomized prospective study, in which uterine washing was administered prior to insemination in patients diagnosed with unexplained infertility.

NCT ID: NCT01999608 Completed - Infertility Clinical Trials

Vitamin D Deficiency and Ovarian Reserve Among Infertile Patients

Start date: August 2013
Phase: N/A
Study type: Observational

The role of vitamin D deficiency in female reproduction remains controversial. Early retrospective studies were inconsistent regarding the effect of serum 25-OH vitamin D levels on pregnancy rates in women undergoing in vitro fertilization (IVF), whereas two retrospective studies postulated that vitamin D deficiency may negatively affect pregnancy rates with an effect mediated through the endometrium. Taking into account that knock-out experiments have shown that vitamin D receptor null mice not only experience uterine hypoplasia but also impaired folliculogenesis, it might be hypothesized that vitamin D deficiency may have a detrimental effect on female ovarian reserve. This may be further supported by previous reports demonstrating that serum 25-OH Vitamin D levels correlates with antimullerian hormone (AMH) levels in women of advanced reproductive age. The aim of this study is to examine through a large set of prospectively recruited infertile women whether serum 25-OH-Vitamin D levels is related with the 2 most widely accepted biomarkers of ovarian reserve: serum AMH levels and antral follicle count (AFC).

NCT ID: NCT01986374 Completed - Infertility Clinical Trials

Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF

Start date: June 2013
Phase: N/A
Study type: Interventional

The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.