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Infertility clinical trials

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NCT ID: NCT06375811 Recruiting - Infertility Clinical Trials

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

PREGnant
Start date: March 16, 2024
Phase: Phase 3
Study type: Interventional

A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate. The investigators' central hypothesis is that in infertile woman with endometriosis undergoing in vitro fertilization-embryo transfer (IVF-ET), live birth rates will improve in those pretreated with GnRH antagonist compared to those not pretreated with GnRH antagonist.

NCT ID: NCT06369415 Recruiting - Infertility Clinical Trials

Health of Babies Born From IVF Versus IVM at 5 Years Old

FM-BABIES-5Y
Start date: April 16, 2024
Phase:
Study type: Observational

The investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after capacitation IVM (CAPA IVM) compared with conventional IVF in order to give strong evidence about the safety of IVM in women with high antral follicle count.

NCT ID: NCT06360471 Recruiting - Cancer Clinical Trials

Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer

Start date: October 1, 2023
Phase:
Study type: Observational [Patient Registry]

To explore whether there is a significant difference in the cumulative live birth rate and maternal and child health outcomes between cancer patients who undergo or do not undergo fertility preservation before receiving anti-tumor treatment and non-cancer patients who undergo assisted reproductive technology treatment/natural pregnancy. This study will be conducted in the Clinical Center of Reproductive Medicine, First Affiliated Hospital of Nanjing Medical University. 2800 women diagnosed with malignant cancers who has desire to reproduce will be enrolled in this study. Statistical analysis of the data will be performed.

NCT ID: NCT06342856 Recruiting - Clinical trials for Infertility Unexplained

Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia

infertility
Start date: June 15, 2023
Phase: Early Phase 1
Study type: Interventional

Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia

NCT ID: NCT06324071 Recruiting - Male Infertility Clinical Trials

Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain). In a previous pilot trial, the ability of TetraSOD® (dose: 250 mg/day) to improve semen characteristics in idiopathic infertile men after three months of treatment was assessed, revealing significant improvements in almost all of the analyzed parameters. In a further clinical trial close to finish (ClinicalTrials.gov Identifier: NCT04864314) using the same dose, such positive results have been tested again in a higher number of patients, and additional parameters have been included in order to gain insights into the sperm physiological changes that underpin the improvement in semen quality. In this new clinical trial, an intermediate dose (125 mg/day) is going to be tested in an attempt to determine a range of TetraSOD® dosage being clinically active for the treatment of male infertility.

NCT ID: NCT06322498 Recruiting - Clinical trials for Cesarean Section Complications

Inflammation Markers in Fluid Aspirate From a Scarred Uterine vs. a Normal Uterine Cavity

Start date: January 18, 2023
Phase: N/A
Study type: Interventional

A prospective study that will take place in the hydrosonography clinic, comparing patients with an intact uterus to those who had a caesarean section. Eligible patients will preform a transvaginal ultrasound for evaluation of presence of a niche. After fixation of the transcervical catheter, we will flush 2 ml sterile NaCl 0.9% into the uterine cavity and aspirate the fluid. After collecting all samples, the samples will be snap frozen and stored at -80o C, until they undergo an immunological analysis.

NCT ID: NCT06321107 Recruiting - Infertility Clinical Trials

Long-term Follow-up Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference

Start date: February 29, 2024
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety of a single injection of GenSci094 during Controlled Ovarian Stimulation up to 1 year old of the infants from previous studies.

NCT ID: NCT06319573 Recruiting - Infertility Clinical Trials

The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization

Start date: March 19, 2024
Phase: N/A
Study type: Interventional

This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.

NCT ID: NCT06304792 Recruiting - Infertility Clinical Trials

Immediate Versus Postponed Single Blastocyst Transfer in Programmed or Stimulated Cycle Frozen Embryo Transfer

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial is to examine whether single blastocyst transfer in the first cycle after oocyte retrieval (immediate) is non-inferior to single blastocyst transfer in a subsequent cycle (postponed) in stimulated or programmed cycle frozen embryo transfer (FET). The primary outcome is live birth rate.

NCT ID: NCT06297070 Recruiting - Fertility Issues Clinical Trials

Lifestyle Care for Fertility Outcome Evaluation

PROWESS
Start date: January 24, 2024
Phase:
Study type: Observational

An observational outcome evaluation of the Lifestyle Care for Fertility program.