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NCT ID: NCT02697162 Withdrawn - Neurogenic Bladder Clinical Trials

Antiseptic-coated Intermittent Urinary Catheter

GuardianCath
Start date: June 2016
Phase: Phase 2/Phase 3
Study type: Interventional

Study design is a prospective, randomised, double-blind, and interventional. Primary aim of the study is to investigate efficacy of antiseptic-coated intermittent hydrophilic urinary catheters in prevention and reduction of catheter-associated urinary tract infections in children with neurogenic bladder. Secondary aim is to assess feasibility of antiseptic-coated intermittent hydrophilic urinary catheters in neurogenic bladder management. Octenidine chloride will be used as antiseptic.

NCT ID: NCT02678234 Withdrawn - Clinical trials for Infections, Respiratory Tract

An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu

Start date: February 1, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the short term efficacy of the Theraflu Aktiv powder for oral solution in the Russian population as compared to an untreated group to support the indication of "Short term relief of the symptoms of colds, chills and influenza, including mild to moderate pain, fever and nasal congestion".

NCT ID: NCT02645201 Withdrawn - Clinical trials for Helicobacter Infections

The Effect of Probiotic Combination on Helicobacter Pylori Infection in Children

Gastrus
Start date: January 2016
Phase: N/A
Study type: Interventional

The combination of two Lactubacillus reuteri strains, ATC 55730 and ATCC PTA 6457 are marketed as GASTRUS® and has been proposed as better option in increasing Helicobacter pylori eradication rate compared to the single strain ATC 55730, due to additional anti-inflammatory properties of the second strain. Objectives of the study are to determine whether adding probiotic combination (GASTRUS®) to an anti- Helicobacter pylori regimen decreases adverse events and increases the eradication rate of Helicobacter pylori in the pediatric population infected with Helicobacter pylori bacteria.

NCT ID: NCT02640469 Withdrawn - Infection Clinical Trials

Alcohol Versus Chlorhexidine With and Without Water

Start date: December 2016
Phase: N/A
Study type: Interventional

Currently at NYU institutions, providine-iodine and chlorhexidine medicated soaps are available as hand disinfection options. The purpose of this study is to determine the relative efficacy of traditional hand scrubs with chlorhexidine with or without rinsing with water after scrubbing is complete versus dry hand rubs with alcohol.

NCT ID: NCT02617706 Withdrawn - Anorectal Surgeries Clinical Trials

Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Colon Surgery

Start date: January 2017
Phase: Phase 2
Study type: Interventional

EPIFLO® unit along with standard wound care vs only standard wound care for Surgical site infections (SSI).

NCT ID: NCT02615379 Withdrawn - Clinical trials for Instrumented Spinal Fusion

Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Instrumented Fusion

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

EPIFLO® unit along with standard wound care vs only standard wound care for Surgical site infections (SSI).

NCT ID: NCT02464306 Withdrawn - Clinical trials for Clostridium Difficile Infection

Fidaxomicin Versus Standard of Care Therapy in Solid Organ Transplant Recipients With Clostridium Difficile Infection

Start date: June 2018
Phase: Phase 4
Study type: Interventional

A prospective study to assess the efficacy and safety of fidaxomicin in Solid Organ Transplant (SOT) recipients (heart, lung, kidney, liver, kidney-pancreas, and pancreas) with a first-episode of Clostridium difficile infection (CDI).

NCT ID: NCT02382419 Withdrawn - Clinical trials for Human Papillomavirus Infection

Carrageenan-Containing Gel in Reducing the Rate of HPV Infection in Healthy Participants

Start date: February 24, 2016
Phase: Phase 2
Study type: Interventional

This randomized phase II trial studies how well carrageenan-containing gel (vaginal gel) works in reducing the rate of human papilloma virus (HPV) infection in healthy participants. Carrageenans, which are naturally derived from seaweed, are enhancements to natural lubrication and may be effective in blocking HPV infection.

NCT ID: NCT02346617 Withdrawn - Clinical trials for Cytomegalovirus Infections

Adoptive Transfer of pp65-specific T Cells for the Treatment of Refractory Cytomegalovirus (CMV) Infection

Start date: January 1, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and efficacy for treatment of persistent CMV infection in hematopoietic cell transplant (HCT) recipients.

NCT ID: NCT02313844 Withdrawn - BK Virus Infection Clinical Trials

Most Closely Human Leukocyte Antigen (HLA)-Matched BK Virus-specific T Lymphocytes (Viralym-B)

Start date: March 1, 2018
Phase: Phase 1
Study type: Interventional

Patients enrolled on this study will have received a stem cell transplant. After a transplant, while the immune system grows back the patient is at risk for infection. Some viruses can stay in the body for life, and if the immune system is weakened (like after a transplant), they can cause life-threatening infections. BK virus (BKV) is a virus that can cause serious life-threatening infections in patients who have weak immune systems. It affects the urinary tract, and can cause frequent urination, blood in the urine, and severe pain. Investigators want to see if they can use a kind of white blood cell called T cells to treat BKV infections that occur after a transplant. Investigators have observed in other studies that treatment with specially trained T cells has been successful when the cells are made from the transplant donor. However as it takes 1-2 months to make the cells, that approach is not practical when a patient already has an infection. Investigators have now generated BKV-specific T cells from the blood of healthy donors and created a bank of these cells. Investigators have previously successfully used frozen virus-specific T cell lines generated from healthy donors to treat virus infections after bone marrow transplant, and have now improved the production method and customized the bank of lines to specifically and exclusively target BKV. In this study, investigators want to find out if the banked BKV-specific T cells derived from healthy donors are safe and can help to treat BK virus infection. The BKV-specific T cells (Viralym-B) are an investigational product not approved by the Food and Drug Administration (FDA).