Hypertension Clinical Trial
Official title:
Prospective Characterization of the Heart, Aorta and Blood Pressure in Women With Turner Syndrome. Association With Aortic Dissection.
Turner syndrome is a congenital complete or partial lack one of the female sex chromosomes
affecting 1 of 2000 live born girls. The syndrome is characterized by an increased
prevalence of ischemic heart disease, aortic dilation and dissection, hypertension, stroke
and autoimmune diseases in general.
Our study aim is:
- Using MRI to further characterize and find risk factors leading to aortic dilation.
- Using MRI to assess the degree of aortic distensibility.
- Using Computed tomography x-ray scanning of the heart and coronary arteries to
characterize the prevalence and degree of ischemic heart disease and coronary
anomalies.
- Using pressure sensitive ultrasound (applanation tonometry) to assess the degree of
aortic stiffness when compared to controls using end points as Pulse Wave Velocity,
Augmentation Index and Central Pulse Pressure.
Turner syndrome is a congenital complete or partial lack one of the female sex chromosomes
affecting 1 of 2000 live born girls. The syndrome is characterized by an increased
prevalence of ischemic heart disease, aortic dilation and dissection, congenital heart
defects, hypertension, stroke, ovarian failure, infertility, decreased final height and
autoimmune diseases in general
Our study aim is:
- Using MRI to further characterize and find risk factors leading to aortic dilation.
- Using MRI to describe aortic dimensions
- Using MRI to assess the degree of aortic distensibility.
- Using Computed tomography x-ray scanning of the heart and coronary arteries to
characterize the prevalence and degree of ischemic heart disease and coronary
anomalies.
- Using pressure sensitive ultrasound (applanation tonometry) to assess the degree of
aortic stiffness when compared to controls using end points as Pulse Wave Velocity,
Augmentation Index and Central Pulse Pressure.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04591808 -
Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and Dyslipidemia
|
Phase 3 | |
| Recruiting |
NCT04515303 -
Digital Intervention Participation in DASH
|
||
| Completed |
NCT05433233 -
Effects of Lifestyle Walking on Blood Pressure in Older Adults With Hypertension
|
N/A | |
| Completed |
NCT05491642 -
A Study in Male and Female Participants (After Menopause) With Mild to Moderate High Blood Pressure to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body and How it Moves Into, Through and Out of the Body After Taking Single and Multiple Doses
|
Phase 1 | |
| Completed |
NCT03093532 -
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
|
N/A | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Completed |
NCT05529147 -
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
|
||
| Recruiting |
NCT05976230 -
Special Drug Use Surveillance of Entresto Tablets (Hypertension)
|
||
| Recruiting |
NCT06363097 -
Urinary Uromodulin, Dietary Sodium Intake and Ambulatory Blood Pressure in Patients With Chronic Kidney Disease
|
||
| Completed |
NCT06008015 -
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1015" and Co-administration of "BR1015-1" and "BR1015-2" Under Fed Conditions in Healthy Volunteers
|
Phase 1 | |
| Completed |
NCT05387174 -
Nursing Intervention in Two Risk Factors of the Metabolic Syndrome and Quality of Life in the Climacteric Period
|
N/A | |
| Completed |
NCT04082585 -
Total Health Improvement Program Research Project
|
||
| Recruiting |
NCT05121337 -
Groceries for Black Residents of Boston to Stop Hypertension Among Adults Without Treated Hypertension
|
N/A | |
| Withdrawn |
NCT04922424 -
Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans Men
|
Phase 1 | |
| Active, not recruiting |
NCT05062161 -
Sleep Duration and Blood Pressure During Sleep
|
N/A | |
| Completed |
NCT05087290 -
LOnger-term Effects of COVID-19 INfection on Blood Vessels And Blood pRessure (LOCHINVAR)
|
||
| Not yet recruiting |
NCT05038774 -
Educational Intervention for Hypertension Management
|
N/A | |
| Completed |
NCT05621694 -
Exploring Oxytocin Response to Meditative Movement
|
N/A | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Recruiting |
NCT05575453 -
OPTIMA-BP: Empowering PaTients in MAnaging Blood Pressure
|
N/A |