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Hypertension clinical trials

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NCT ID: NCT03783650 Terminated - Clinical trials for Pediatric Hypertension

Boosting Primary Care Awareness and Treatment of Childhood Hypertension

BP-CATCH
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

The proposed research, building on an ongoing AHRQ-funded research project to prevent pediatric diagnostic errors in primary care (R01HS023608) and using a prospective, cluster-randomized, stepped wedge design, will investigate whether 1) a quality improvement collaborative (QIC) intervention without subspecialist involvement, 2) a QIC with subspecialists and primary care physicians (PCPs) mutually engaged, and/or 3) a hub and spoke co-diagnosis, co-management model where PCPs diagnose and manage pediatric hypertension (HTN) with a supporting subspecialist advisor, reduce errors in pediatric HTN diagnosis and management compared to each other and usual care.

NCT ID: NCT03742219 Terminated - Hypertension Clinical Trials

Peru Longitudinal Study

Start date: June 5, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the change in disease prevalence over time in impoverished urban communities in Lima, Peru.

NCT ID: NCT03741608 Terminated - Hypertension Clinical Trials

B'More for a Peaceful Motherhood Hypertension Control Study

Start date: January 22, 2019
Phase: N/A
Study type: Interventional

This study will assess whether an intervention including mindfulness, dietary education, and smoking cessation can help African-American women of childbearing age (age 18-44) with hypertension or high blood pressure to lower their blood pressure. The investigators propose to screen women of childbearing age for hypertension, and to invite women to participate in an intervention to reduce their blood pressure. The investigators will track their perceived stress and their blood pressure levels over the next 6 months. Half of the women who participate will be given a blood pressure cuff and taught to measure their own blood pressure. More frequent tracking of blood pressure will be done in these women.

NCT ID: NCT03730519 Terminated - Clinical trials for Hypertension, Resistant to Conventional Therapy

UK Registry for Baroreflex Activation Therapy

UK-BAT
Start date: November 1, 2018
Phase: N/A
Study type: Interventional

This study is a post-marketing open label single arm, single centre clinical trial of electrical carotid sinus stimulation with the Barostim Neo device to target sub-optimally controlled arterial hypertension or highly variable blood pressure in patients for whom no alternative therapies are available.

NCT ID: NCT03709771 Terminated - Hypertension Clinical Trials

Novel Mechanisms and Predictors of VEGF Receptor Inhibitor- or Immune Checkpoint Inhibitor-Associated Hypertension and Cardiovascular Disease

Start date: January 9, 2020
Phase:
Study type: Observational

The purpose of this study is to understand the effect of vascular endothelial growth factor tyrosine kinase (VEGF) inhibitor, immune checkpoint-inhibitor (ICI), and combination treatment on blood pressure and blood vessel function.

NCT ID: NCT03689244 Terminated - Clinical trials for Chronic Thromboembolic Pulmonary Hypertension

A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment

SELECT
Start date: January 23, 2019
Phase: Phase 3
Study type: Interventional

Selexipag is available in many countries for the treatment of pulmonary arterial hypertension (PAH). Due to the similarities between PAH and chronic thromboembolic pulmonary hypertension (CTEPH) and the observed efficacy of other PAH medicines in CTEPH, it is believed that selexipag could benefit to patients with CTEPH. This study aims to assess the efficacy and safety of selexipag in participants with inoperable or persistent/recurrent CTEPH.

NCT ID: NCT03673774 Terminated - Clinical trials for Pulmonary Hypertension

Impedancemetry in Patients Monitored for Pulmonary Hypertension

HPepic
Start date: August 23, 2017
Phase: N/A
Study type: Interventional

Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension

NCT ID: NCT03667781 Terminated - Hypertension Clinical Trials

Therapeutic Drug Monitoring of Cardiac Medications

Start date: August 1, 2018
Phase:
Study type: Observational

The investigators will interview patients and providers of patients who have hypertension and are seen in cardiology clinic about ways to discuss therapeutic drug monitoring with patients. The investigators will use these interviews to crease discussion tools to discuss therapeutic drug monitoring. The investigators will then draw one venous blood sample in a different group of patients who are seen in interventional clinic for 1 month followup after PCI. The investigators will assay this blood for therapeutic drug monitoring and will provide the results to their providers for discussion at their regularly scheduled followup cardiology visit. The investigators will have the patients and providers fill out a survey afterwards to determine how they viewed therapeutic drug monitoring.

NCT ID: NCT03660618 Terminated - Stroke Clinical Trials

LSFG-SKIN, Laser Speckle Flowgraphy

Start date: May 23, 2017
Phase: N/A
Study type: Interventional

The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or environmental changes, such as temperature, light and pressure.

NCT ID: NCT03657095 Terminated - Clinical trials for Pulmonary Arterial Hypertension

A Study With BPS-314d-MR-PAH-303 in Participants With Pulmonary Arterial Hypertension

BEAT OLE
Start date: December 10, 2018
Phase: Phase 3
Study type: Interventional

This is a multi-center, open-label study for eligible participants who were actively participating in the BPS-314d-MR-PAH-302 double-blind study (NCT01908699) at the time the study was concluded. This open-label extension (OLE) study will evaluate the safety, tolerability, and efficacy of long-term treatment with esuberaprost sodium tablets (Beraprost Sodium 314d Modified Release tablets).