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Hypertension clinical trials

View clinical trials related to Hypertension.

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NCT ID: NCT04010669 Not yet recruiting - Portal Hypertension Clinical Trials

The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection

Start date: August 1, 2019
Phase: Phase 3
Study type: Interventional

The purpose of the present clinical trial is to study the effect of somatostatin in the regulation of velocity and blood flow of the hepatic circulation in patients undergoing liver resection. The patients will be randomized in two groups: the study group will receive somatostatin and the control group will receive the placebo. In both groups, patients will undergo hepatectomy and directly postoperatively they will receive either somatostatin or placebo, depending on their randomization. The primary endpoint will be the increase or decrease of the velocity and the flow of the hepatic circulation estimated by ultrasonography compared to the same parameters when measured preoperatively.

NCT ID: NCT03988894 Not yet recruiting - Hypertension Clinical Trials

mDASHNa-CC APP to Support a Healthy Diet and Hypertension Control for Chinese Canadian Seniors

Start date: January 10, 2020
Phase: Early Phase 1
Study type: Interventional

The aim of this proposed study is to translate the Dietary Approach to Stop Hypertension with Sodium (Na) Reduction for Chinese Canadian (DASHNa-CC), a classroom-based antihypertensive dietary educational intervention, to an innovative smartphone app (mDASHNa-CC) to enable Chinese Canadian seniors' access to this antihypertensive dietary intervention anytime, regardless of where they are.

NCT ID: NCT03963934 Not yet recruiting - Clinical trials for Arterial Hypertension

Feasibility of a Program on a Nurse-led Telephone 6-month-follow-up for Uncontrolled Hypertensive Women

PreDynamiques
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

This study evaluate the feasibility of a 6-month personalized support program for hypertensive and non-observant women, led by nurses by telephone follow-up.

NCT ID: NCT03946605 Not yet recruiting - Clinical trials for Hypertension, Insomnia

Sleep Quality and Mechanisms of Cardiovascular Risks in Adult With Hypertension

Start date: July 2019
Phase: N/A
Study type: Interventional

The objective of this study is to elucidate the potential mechanisms responsible for the increased risk of cardiovascular disease among patients with hypertension and comorbid insomnia.

NCT ID: NCT03888170 Not yet recruiting - Pregnancy Clinical Trials

The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity

Start date: April 2019
Phase:
Study type: Observational

The investigators seek to describe the composition, architecture, and electrical conduction properties of the human uterine myometrial artery and their impact on vascular reactivity upon exposure to hypertensive stress. Non-pregnant women and pregnant women with and without hypertensive complications will be studied to evaluate the influence of these states on the myometrial arteries. Vascular over-reactivity and disruption of the normal pregnancy-associated physiologic changes of relaxed vascular tone possess the potential for non-compensated blood flow to the uterus and placenta that is insufficient to meet the metabolic demands of a growing placenta. With an understanding of these changes, the research team will be able to propose basic mechanistic changes of pathologic myogenic tone that may ultimately be investigated as potentially modifiable processes to reduce the development and/or severity of these pregnancy complications (gestational hypertension, preeclampsia, eclampsia, small for gestational age, intrauterine growth restriction and intrauterine fetal demise. ).

NCT ID: NCT03885843 Not yet recruiting - Clinical trials for Cardiovascular Diseases

Sympathetic Mapping/ Ablation of Renal Nerves Trial (SMART) HTN-OFF MED Study

SMART OFF-MED
Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of selected renal sympathetic denervation using SyMapCath I™ Catheter and SYMPIONEER S1™ Stimulator/Generator in patients with hypertension in the absence of antihypertensive medications, or till the negative result was given by urinary antihypertensive drugs detection of high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) after at least two weeks of drug elution period. Then Office systolic blood pressure (SBP) is still ≥ 150mmHg, < 180mmHg, diastolic blood pressure (DBP) ≥ 90mmHg, and 24-hour mean SBP of ambulatory blood pressure measurement (ABPM) is ≥130mmHg, or day-time mean SBP ≥135mmHg, or night-time mean SBP ≥120mmHg, and all SBP of ABMP record <170mmHg. After then the patient will be included when the results of bilateral renal angiography meet the requirements of renal nerve stimulation, mapping and denervation conditions.

NCT ID: NCT03876418 Not yet recruiting - Clinical trials for Intra-Abdominal Hypertension

Surveillance, Prevention and Treatment of Intra-abdominal Hypertension and Abdominal Compartment Syndrome

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study evaluates the efficacy of intensive surveillance, prevention and treatment of intra-abdominal hypertension in ICU patients. In the first two months patients will be screened and undergo usual care. In the following 10-months patients will have more intensive screening and active measures towards prevention and treatment according to best practices.

NCT ID: NCT03860220 Not yet recruiting - Hypertension Clinical Trials

The Efficacy and Safety of Triple Therapy of Telmisartan/Amlodipine/Rosuvastatin

Start date: March 1, 2019
Phase: Phase 4
Study type: Interventional

The goal of this study was to assess the efficacy and safety of FDC therapy with triple therapy of Telmisartan 40 mg/Amlodipine 5 mg/Rosuvastatin 10mg in Korean patients with both hypertension and dyslipidemia.

NCT ID: NCT03849287 Not yet recruiting - Hypertension Clinical Trials

Compare the Pharmacokinetics and Safety of CKD-333 With Co-administration CKD-330 and D090 in Healthy Male Adults

Start date: February 25, 2019
Phase: Phase 1
Study type: Interventional

The object of clinical trial is to investigate the pharmacokinetics and safety compared to CKD-333 and co-administration CKD-330, D090 under fasting condition in healthy male adults.

NCT ID: NCT03810443 Not yet recruiting - Clinical trials for Pulmonary Arterial Hypertension

Prevalence of the Hyperventilation Syndrome in Pulmonary Arterial Hypertension

HYPER2
Start date: January 14, 2019
Phase: N/A
Study type: Interventional

Dyspnea is a major symptom in pulmonary arterial hypertension and people with the same haemodynamic have generally different degree of dyspnea in pulmonary arterial hypertension. The hyperventilation syndrome is a frequent cause of dyspnea in general population and in respiratory diseases like asthma but has never been studied in pulmonary hypertension. The goal of this study is to measure the prevalence of pulmonary hypertension in a population of patients with controlled pulmonary arterial hypertension (PAH).