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Hypertension clinical trials

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NCT ID: NCT05186831 Completed - Hypertension Clinical Trials

Patient-Portal vs Text-based Hypertension Monitoring Among Black Medicaid/Medicare Patients

Start date: October 19, 2020
Phase: N/A
Study type: Interventional

The coronavirus disease 2019 (COVID-19) pandemic has uprooted conventional health care delivery for routine ambulatory care, requiring health systems to rapidly adopt telemedicine capabilities. The digital divide, has been well documented with lower rates of technology and broadband adoption among racial/ethnic minorities. Additionally, Black patients suffer a disproportionate burden of hypertension and cardiovascular disease. This study will implement a text-based home hypertension monitoring program among Black Medicaid patients with hypertension and cardiovascular disease (CVD) and compare its uptake to the currently available blood pressure monitoring program using the patient portal that is integrated into the electronic health record (EHR).

NCT ID: NCT05185297 Completed - Hypertension Clinical Trials

Recreational Futsal for Controlled Hypertension

HyperFut
Start date: November 17, 2021
Phase: N/A
Study type: Interventional

Arterial hypertension (HT) was the leading global contributor for premature deaths in 2015. Its treatment includes medication and lifestyle changes, namely diet and regular exercise, which has shown to have an inverse relationship with arterial HT. Recreational soccer (RS) has proven to be a non-pharmacological treatment for several chronic conditions, including arterial HT, with meaningful decreases on blood pressure (BP). Recreation futsal (RF) is expected to elicit comparable BP changes to RS considering that it imposes similar physical and physiological demands. However, the effects of RF on BP and other cardiovascular markers have not been previously investigated in participants only with controlled arterial HT. Furthermore, acute BP changes and double product elicited by this exercise modality were never described. Therefore, the main purpose of this study is to assess if RF is an effective coadjuvant intervention for BP control in adults with controlled arterial HT. Secondary purposes are: i) to determine the impact of RF on other cardiovascular markers; ii) to describe the acute BP changes and the double product elicited by RF; and iii) to assess the impact of 1 month of detraining on BP and other cardiovascular markers (4 months).

NCT ID: NCT05185011 Completed - Clinical trials for Pulmonary Arterial Hypertension

Study of the Pharmacokinetics and Safety of TPN171H Tablets in Subjects With Mild ,Moderate Hepatic Insufficiency and Normal Liver Function

Start date: December 16, 2021
Phase: Phase 1
Study type: Interventional

The study aims to investigate and compare the effect of TPN171H on subjects with mild and moderate hepatic impairment compared to healthy subjects.

NCT ID: NCT05181046 Completed - Glaucoma Clinical Trials

Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients

Start date: November 6, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of microdrops vs. standard eyedrops of 0.5% timolol maleate in adults with primary open-angle glaucoma or ocular hypertension in terms of intraocular pressure-lowering efficacy and cardiovascular side effects.

NCT ID: NCT05176951 Completed - Clinical trials for Pulmonary Hypertension

A Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease

Start date: December 22, 2022
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of treprostinil palmitil inhalation powder (TPIP) compared with placebo

NCT ID: NCT05170061 Completed - Hypertension Clinical Trials

24 Hour Ambulatory Cardiac Oxygen Consumption

Start date: February 2013
Phase: Phase 3
Study type: Interventional

A randomized,double-blind,double-dummy,active controlled,15 week study to evaluate the effects of nebivolol and valsartan alone and in combination on 24-hour ambulatory cardiac work and variability of heart rate-mean central systolic pressure product.

NCT ID: NCT05168059 Completed - High Blood Pressure Clinical Trials

Clevidipine in Neurocritical Patients

NEURO-CLEV
Start date: January 1, 2017
Phase:
Study type: Observational

Acute blood pressure elevation is a frequent problem in neurocritical patients. Its effective management is challenging and must avoid significant decreases of blood pressure leading to lower cerebral perfusion pressure worsening ischemia and elevations probably associated with bleeding, rebleeding or hematoma expansion associated with poor prognosis

NCT ID: NCT05165823 Completed - Clinical trials for Hypertension,Essential

The Significance of Sodium Balance and the Value of Salt-blood Test in Identifying Salt Sensitive Patients

VASA
Start date: February 8, 2022
Phase: N/A
Study type: Interventional

This is a randomized controlled trial with 72 patients with hypertension examining the effects on blood pressure of sodium restriction and whether the blood analysis Salt-blood test is associated to a decrease in blood pressure. Patients will be randomized 2:1 to either sodium restriction or usual diet for 4 weeks. Baseline measures will be done before intervention and outcome measures after the 4 weeks.

NCT ID: NCT05158569 Completed - Hypertension Clinical Trials

Comparison of Breathing Exercise for Hypertensive Patients

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

To determine the Effectiveness of diaphragmatic breathing vs. slow breathing techniques on blood pressure and Quality of life in adults with stage 1 hypertension. In accessible literature limited data was found on the comparison of different breathing techniques. The current study will compare the effect of slow vs. diaphragmatic breathing exercises and will demonstrate which one is more effective.

NCT ID: NCT05155852 Completed - Preeclampsia Clinical Trials

Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women With Postpartum Hypertension

Start date: August 13, 2021
Phase:
Study type: Observational

The purpose of this research study is to develop a protocol for NIRS-based bedside monitoring to identify impaired cerebral autoregulation in women admitted to the high-risk obstetrics unit with postpartum hypertension. The investigators will then pilot this protocol in 10 patients with high-risk neurological features, such as headache.