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Hypertension clinical trials

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NCT ID: NCT05955339 Recruiting - Hypertension Clinical Trials

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

CHRONICLE
Start date: January 24, 2024
Phase: N/A
Study type: Interventional

CHRONICLE is a randomized trial assessing the comparative effectiveness of providing written visit information via the patient portal (NOTES) versus NOTES plus visit audio recording (AUDIO) to older adult patients with chronic diseases on quality of life and other outcomes. During the trial, the team will also invite caregivers identified by patients to join the project.

NCT ID: NCT05955040 Recruiting - Clinical trials for Elevated Blood Pressure

Treatment of Elevated Blood Pressures in Early Pregnancy

Start date: July 11, 2023
Phase: Phase 2
Study type: Interventional

This is a randomized controlled trial comparing the outcomes of treatment and non-treatment of elevated blood pressures in early pregnancy.

NCT ID: NCT05951166 Recruiting - Clinical trials for Heart Failure Patients With Pulmonary Hypertension

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension

PreVail-PH
Start date: May 5, 2023
Phase: N/A
Study type: Interventional

Prospective, single-arm, multicenter First in Human study to characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Pulmonary Hypertension

NCT ID: NCT05947448 Recruiting - Clinical trials for Essential Hypertension

Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study

Start date: January 22, 2024
Phase:
Study type: Observational [Patient Registry]

This is a national multicenter, prospective, observational study. It is planned to enroll 1215 patients with newly diagnosed essential hypertension in 80 centers, and divide them into 3 groups according to different treatment plans given by doctors: AZL-M monotherapy group, CCB monotherapy group (amlodipine besylate tablets or nifedipine controlled-release tablets) and AZL-M+CCB (amlodipine besylate tablets or nifedipine controlled-release tablets) combined treatment group. Subjects were visited 4 times at baseline, 1 month, 3 months, and 6 months, and the following key indicators of subjects were measured according to the doctor's decision, and the measurement results were collected

NCT ID: NCT05942729 Recruiting - Cardiomyopathies Clinical Trials

Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.

ORCHID
Start date: January 1, 2023
Phase:
Study type: Observational

Research hypothesis - Recent studies have shown that high-dimensional descriptors of the cardiac function can be efficiently exploited to characterize targeted pathologies. In this project, the investigators hypothesize that echocardiograms possess a wealth of information that is currently under-exploited and that, combined with relevant patient data, will allow the development of robust and accurate digital tools for etiological diagnosis. Objectives - Based on key advances recently obtained in image analysis, notably by members of the consortium, the objective of this project is to develop rigorous and explainable cardiac disease prediction models from echocardiography based on the transformer paradigm (AI). The strength of this study lies in the development of a strong AI framework to model the complex interactions between high-quality image-based measurements extracted from echocardiograms and relevant patient data to automatically predict etiological diagnosis of cardiac diseases

NCT ID: NCT05937685 Recruiting - Stroke Clinical Trials

Reducing Blood Pressure in Patients With High Cardiovascular Risk in the Safety-Net

BP-REACH
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

BP-REACH is a study of a team-based (pharmacist and health coach) program for lowering blood pressure for people with a prior stroke or heart attack in the Los Angeles Department of Health Services public healthcare system. The goal of this clinical trial is to test if this team based program is better at helping people reduce their blood pressure than usual care for people with prior heart attack or stroke. The main questions it aims to answer are: - Do people in the REACH BP program have lower blood pressure at 12 months compared to those getting usual care? - Do people in the REACH BP program have better Life's Essential 8 scores and patient experience compared to those getting usual care?

NCT ID: NCT05935865 Recruiting - Clinical trials for Pulmonary Hypertension

Monitoring of the Influence of Approved PH-therapies RV-PA Coupling

Start date: February 13, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the acute (days) changes in right ventricular functions caused by initiation of pharmacological therapies in patients with precapillary pulmonary hypertension. The main question it aims to answer is: • Course of afterload and intrinsic contractility throughout the hospital stay Participants will be equipped with a device for continuous monitoring and recording of the right ventricular pressure signal.

NCT ID: NCT05935605 Recruiting - Clinical trials for Pulmonary Hypertension

Pulmonary Hypertension in Left Heart Disease

Start date: July 20, 2023
Phase:
Study type: Observational

The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.

NCT ID: NCT05934526 Recruiting - Clinical trials for Pulmonary Arterial Hypertension

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Start date: December 28, 2023
Phase: Phase 3
Study type: Interventional

The primary objective of the study is to determine the effect of seralutinib on improving exercise capacity in subjects with WHO Group 1 PAH who are FC II or III. The secondary objective for this trial is to determine time to clinical worsening.

NCT ID: NCT05931003 Recruiting - Hypertension Clinical Trials

Reconstruction of the Carotid Bifurcation in Patients With Arterial Hypertension of 2-3 Degrees

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Carotid endarterectomy (CEA) is a well-established procedure for preventing ischemic brain damage. Stenosis of the precerebral vessels are often combined with arterial hypertension. In recent decades, many works have appeared that indicate that the course of arterial hypertension (AH) changes after CEA. However, it remains unknown how this is related to the choice of surgical tactics.