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Hypersensitivity clinical trials

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NCT ID: NCT05309967 Completed - Dentin Sensitivity Clinical Trials

Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening

Start date: March 13, 2021
Phase: N/A
Study type: Interventional

Tooth whitening is one of the most indicated aesthetic procedures in dentistry and there is evidence that it interferes with aspects of patients' quality of life. However, the sensitivity, associated with the post-procedure period, challenges clinicians and researchers. The use of topic desensitizing agents could be a alternative for the control of this adverse effects of bleaching agents. The objective of this randomized clinical study, therefore, is to evaluate the effect of glutaraldehyde-based desensitizing agent associated on tooth sensitivity and tooth color after bleaching with 35% hydrogen peroxide. 25 patients will be selected divided into two groups for a double-blind and split-mouth study. Among the results it is expected: that the use of glutaraldehyde desensitizing agent helps in the control of post-bleaching sensitivity, without harming the final color obtained of patients submitted to the proposed clinical protocol.

NCT ID: NCT05302700 Completed - Attachment Clinical Trials

Effectiveness of Early Parental Sensitivity Intervention for Preterm Infant Mothers

Start date: November 2, 2022
Phase: N/A
Study type: Interventional

In Taiwan, according to the birth notification statistics of the Ministry of Health and Welfare. 164,496 newborns were born in 2020, with preterm births accounting for about 11.58%.Most preterm infants need to be hospitalized for highly specialized care, resulting in the separation of preterm infants from their parents after birth, which may have a negative impact on the healthy attachment development between parents and preterm infants. Moreover, due to the vulnerability of preterm infants, parents often lack the confidence to take care of them.

NCT ID: NCT05301647 Completed - Quality of Life Clinical Trials

Mometasone Furoate Nasal Spray in Italian Children

Start date: June 20, 2019
Phase:
Study type: Observational

Objective Seasonal allergic rhinitis (SAR) is a common disease in childhood and characterized by type 2 inflammation, bothersome symptoms, and impaired quality of life (QoL). Intranasal corticosteroids are effective medications in managing SAR patients. In addition, mometasone furoate nasal spray (MFNS) is a well-known therapeutic option. However, the literature provided no data about its effects in European children with SAR. Thus this study addressed this unmet need.

NCT ID: NCT05298917 Completed - Cornea Clinical Trials

Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Soft contact lens wear reduces the amount of oxygen reaching the eye, which may have an influence on corneal sensitivity. The aim of this study is to measure corneal sensitivity with means of liquid jet esthesiometry at baseline and after 6 days of continuous, extended contact lens wear.

NCT ID: NCT05289479 Completed - Clinical trials for The Effect of Preheating Cycles of Resin Composite on Both Hypersensitivity and Clinical Performance

Pre-heated Resin Composite Restoration

Start date: January 30, 2021
Phase: N/A
Study type: Interventional

this study is conducted to evaluate the post-operative hypersensitivity and clinical performance of preheated resin composite with different number of pre-heating cycles in class II carious lesions compared to resin composite restorations without preheating using Modified US Public Health Service Clinical Criteria (USPHS).

NCT ID: NCT05284565 Completed - Allergy Clinical Trials

Comparative Study of Skin Prick Allergy Test Measurements Between Current Manual Procedure and Nexkin DSPT Device

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

Clinical trial with the aim to evaluate the level of agreement in wheal size measures in allergy skin prick testing (SPT) between the electro-medical device Nexkin DSPT® and the manual measurement procedure used in the daily practice.

NCT ID: NCT05269082 Completed - Clinical trials for Drug Hypersensitivity

A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults

Start date: April 5, 2022
Phase:
Study type: Observational

The aim of this study is to find out whether TAK-880 creates hypersensitivity reactions compared to Gammagard S/D by testing blood taken from participants who have a higher risk of becoming hypersensitive to immunoglobulin products. This study is about collecting data available in the participant's medical record. No study medicines will be provided to participants in this study. Each participant will fill out a study questionnaire during a routine doctor visit. Blood will be taken from participants who have a higher risk of developing hypersensitivity reactions to immunoglobulin products.

NCT ID: NCT05258721 Completed - Periodontitis Clinical Trials

Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP

Start date: July 6, 2021
Phase: Phase 2
Study type: Interventional

90-day, self-controlled, longitudinal, non-blinded clinical trial which will measure changes in clinical parameters in participants with gingivitis and Stage I or II periodontitis who apply ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse.

NCT ID: NCT05245175 Completed - Allergic Rhinitis Clinical Trials

Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions

SIMBA
Start date: February 22, 2022
Phase: N/A
Study type: Interventional

Single-blind, within-block randomized, clean-air-controlled study to assess the effect of lactose and sodium chloride particles in patients with allergic rhinitis on nasal symptoms when challenged in the Fraunhofer Allergen Challenge Chamber

NCT ID: NCT05243953 Completed - Clinical trials for Post-Traumatic Headache

Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache

Start date: March 21, 2022
Phase: N/A
Study type: Interventional

The aim is to investigate whether opening of ATP-sensitive potassium (KATP) channels induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).