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Hyperglycaemia (Diabetic) clinical trials

View clinical trials related to Hyperglycaemia (Diabetic).

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NCT ID: NCT05597605 Completed - Clinical trials for Diabetes Mellitus, Type 2

The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

The objectives of SHINE study are to confirm the safety aspects of the SHINE SYSTEM. Moreover, the goal of this clinical investigation is the initial evaluation of sensor's performance by assessing sensor's ability to qualitatively detect the appropriate analytes in subjects with diabetes of 18 years and older.

NCT ID: NCT04343040 Not yet recruiting - Clinical trials for Bariatric Surgery Candidate

Perioperative Evaluation of Glucose Profile Using Continuous Glucose Monitoring System in Glucose Intolerant Patients

PERISURG-CGM
Start date: September 2022
Phase: N/A
Study type: Interventional

The recent use of a pre-operative carbohydrate loading compared to fasting has been shown to improve the early recovery after surgical procedures by reducing the profound stress response following surgery and allowing a better postoperative blood glucose regulation by lowering insulin resistance. The responsible mechanisms of T2D remission after bariatric surgery are not completely understood and guidelines for the early management of T2D and GI following bariatric surgery are lacking, resulting in highly variable postoperative glucose control. No other study has yet investigated the effect of preoperative carbohydrate loading on glucose control the first days after the bariatric surgery in patients who have poor glycemic control

NCT ID: NCT04011683 Completed - Type 1 Diabetes Clinical Trials

Hypoglycaemia and Cardiac Arrhythmias in Type 1 Diabetes

Hypo-Heart-1
Start date: December 1, 2018
Phase:
Study type: Observational

The investigators hypothesise that patients with type 1 diabetes have clinically relevant, but often unrecognised, episodes of arrhythmias linked to episodes of hypoglycaemia and/or clinically significant fluctuations in plasma glucose.

NCT ID: NCT03708887 Recruiting - Hyperlipidemias Clinical Trials

The Effect of Omega-3 FA on Glucose and Lipid Homeostasis Disorders in Obese/Diabetic Patients

Start date: March 1, 2019
Phase: Phase 4
Study type: Interventional

A double-blind and placebo-controlled study was conducted in current human study. The purpose of this study is to investigate the effects of n-3 PUFA intervention on glucose and lipid homeostasis in Chinese diabetic/obese patients.

NCT ID: NCT03469492 Completed - Clinical trials for Hyperglycaemia (Diabetic)

Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose

Start date: January 18, 2018
Phase: Early Phase 1
Study type: Interventional

To investigate whether longer-term improvement of glycemic control in poorly controlled diabetes patients with a 12-week intensified insulin treatment regimen will lead to decreased polyol pathway activity.

NCT ID: NCT03414892 Completed - Clinical trials for Type 2 Diabetes Mellitus

Multiple Ascending Doses of Globalagliatin Hydrochloride in Type 2 Diabetes Mellitus

Start date: January 3, 2018
Phase: Phase 1
Study type: Interventional

This is a phase I placebo-controlled study to assess safety, tolerability, pharmacokinetics and pharmacodynamics of Globalagliatin Hydrochloride (SY-004) after Multiple Ascending Doses in patients with Type 2 Diabetes Mellitus (T2DM).

NCT ID: NCT03404180 Recruiting - Hypertension Clinical Trials

Peripheral Nerve Blocks for Above-the-knee Amputations

Start date: February 9, 2018
Phase: Phase 4
Study type: Interventional

Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).

NCT ID: NCT03356457 Completed - Clinical trials for Hyperglycaemia (Diabetic)

Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes

Start date: November 30, 2017
Phase: Early Phase 1
Study type: Interventional

To determine the effect of re-activation of brain glucose metabolism induced by dichloroacetate (DCA) on cognitive function and counterregulatory hormone responses in patients with type 1 diabetes (T1DM) with recurrent hypoglycemia.

NCT ID: NCT03171623 Completed - Healthy Volunteers Clinical Trials

The Assessment of Single-Dose Safety,Tolerability, Pharmacokinetics and Pharmacodynamic of Globalagliatin Hydrochloride

Start date: April 5, 2017
Phase: Phase 1
Study type: Interventional

This is a phase 1 randomized,double-blind,placebo-controlled study with single oral dose of globalagliatin hydrochloride (SY-004) administered to chinese healthy subjects to evaluated the safety, tolerability, pharmacokinetics and pharmacodynamics of globalagliatin hydrochloride (SY-004).

NCT ID: NCT03152890 Recruiting - Clinical trials for Liver Transplantation

Insulin Therapy for Postreperfusion Hyperglycemia

INS_LTPL
Start date: May 15, 2017
Phase: Phase 4
Study type: Interventional

Glycemic control during liver transplantation is challenging especially after reperfusion of the liver graft. Insulin dose to treat postreperfusion hyperglycemia is retrospectively analyzed using historical data. The proposed dose then is prospectively applied to the patients to assess the adequacy of the insulin dose.