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Hyperglycaemia (Diabetic) clinical trials

View clinical trials related to Hyperglycaemia (Diabetic).

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NCT ID: NCT05597605 Completed - Clinical trials for Diabetes Mellitus, Type 2

The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

The objectives of SHINE study are to confirm the safety aspects of the SHINE SYSTEM. Moreover, the goal of this clinical investigation is the initial evaluation of sensor's performance by assessing sensor's ability to qualitatively detect the appropriate analytes in subjects with diabetes of 18 years and older.

NCT ID: NCT04011683 Completed - Type 1 Diabetes Clinical Trials

Hypoglycaemia and Cardiac Arrhythmias in Type 1 Diabetes

Hypo-Heart-1
Start date: December 1, 2018
Phase:
Study type: Observational

The investigators hypothesise that patients with type 1 diabetes have clinically relevant, but often unrecognised, episodes of arrhythmias linked to episodes of hypoglycaemia and/or clinically significant fluctuations in plasma glucose.

NCT ID: NCT03469492 Completed - Clinical trials for Hyperglycaemia (Diabetic)

Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose

Start date: January 18, 2018
Phase: Early Phase 1
Study type: Interventional

To investigate whether longer-term improvement of glycemic control in poorly controlled diabetes patients with a 12-week intensified insulin treatment regimen will lead to decreased polyol pathway activity.

NCT ID: NCT03414892 Completed - Clinical trials for Type 2 Diabetes Mellitus

Multiple Ascending Doses of Globalagliatin Hydrochloride in Type 2 Diabetes Mellitus

Start date: January 3, 2018
Phase: Phase 1
Study type: Interventional

This is a phase I placebo-controlled study to assess safety, tolerability, pharmacokinetics and pharmacodynamics of Globalagliatin Hydrochloride (SY-004) after Multiple Ascending Doses in patients with Type 2 Diabetes Mellitus (T2DM).

NCT ID: NCT03356457 Completed - Clinical trials for Hyperglycaemia (Diabetic)

Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes

Start date: November 30, 2017
Phase: Early Phase 1
Study type: Interventional

To determine the effect of re-activation of brain glucose metabolism induced by dichloroacetate (DCA) on cognitive function and counterregulatory hormone responses in patients with type 1 diabetes (T1DM) with recurrent hypoglycemia.

NCT ID: NCT03171623 Completed - Healthy Volunteers Clinical Trials

The Assessment of Single-Dose Safety,Tolerability, Pharmacokinetics and Pharmacodynamic of Globalagliatin Hydrochloride

Start date: April 5, 2017
Phase: Phase 1
Study type: Interventional

This is a phase 1 randomized,double-blind,placebo-controlled study with single oral dose of globalagliatin hydrochloride (SY-004) administered to chinese healthy subjects to evaluated the safety, tolerability, pharmacokinetics and pharmacodynamics of globalagliatin hydrochloride (SY-004).

NCT ID: NCT01818674 Completed - Obesity Clinical Trials

Microclinic Social Network Behavioral Health Trial in Jordan

Start date: January 2012
Phase: N/A
Study type: Interventional

This 3-armed randomized controlled trial aims to evaluate the effectiveness of The Microclinic Behavioral Health Program in improving obesity and diabetes risk factors through a behavioral intervention program structured to enhance and promote social-network interactions and social support. The full version of the Microclinic Behavioral Health Program (Full MCP) with program-activated social-network interactions-with shared access to diabetes education, technology, and group support to promote weight and metabolic control through diet, exercise, medication adherence, and blood pressure management. Participants play a role in the collective effort to combat diabetes and solidifying self-management behavioral skills through peer-monitoring and encouragement of lifestyle behaviors. The study may yield valuable information on the impact of social support and social network interactions for enhancing body weight and blood sugar control. We compare the full MCP intervention, to a basic MCP intervention with more limited classroom interaction, and to an parallel monitoring control arm. And we aim to understand how metabolic changes over time relate to the cross-propagation of health behaviors between persons in social networks. This Microclinic Behavioral Health Program was established in collaboration with the Royal Health Awareness Society (RHAS) and the Jordanian Ministry of Health (MoH).