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Clinical Trial Summary

The goal of TIARAS is to understand whether addressing trauma in the context of economic insecurity can produce durable reductions in HIV risk among women who inject drugs.


Clinical Trial Description

TIARAS is a multi-component behavioral intervention designed to reduce HIV acquisition risk among women who inject drugs. All participants will receive contingency management, an evidenced-based intervention to reduce drug use and HIV risk will be utilized to incentivize daily directly observed pre-exposure prophylaxis doses doses and stimulant/opioid abstinence. Half of the participants will be randomized to receive expressive writing exercises, and evidenced-based intervention that addresses trauma while the other half will complete neutral writing exercises. During the course of twelve months, we will use surveys, interviews, and biological specimen collection to understand whether expressive writing can boost and extend the effects of contingency management for PrEP and stimulant/opioid abstinence on HIV acquisition risk among women who inject drugs. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05192434
Study type Interventional
Source Drexel University
Contact Alexis M Roth, PhD, MPH
Phone 317-213-3960
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date February 2022
Completion date September 2025

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