Tajik Migrant Health Education Study

HIV Infections Clinical Trial

Official title:

MASLIHAT Intervention for Tajik Male Migrants Who Inject Drugs

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04853394
• Other study ID #: 2020-0795
• Secondary ID: R01DA050464
• Status: Completed
• Phase: N/A
• Start date: October 19, 2021
• Est. completion date: May 28, 2023

Study information

• Verified date: March 2024
• Source: University of Illinois at Chicago
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will test the efficacy of a peer-education prevention intervention to reduce risky drug, alcohol, and sexual behaviors among male Tajik labor migrants who inject drugs (MWID) while working in Moscow. The peer educator intervention will be compared to a health education control intervention. Each intervention consists of 5 weekly 2-hour small group sessions. Follow-up assessments will be conducted at 3, 6, 9, and 12 months after the intervention. It is hypothesized that, compared to MWID who receive the health education control intervention, those who receive the peer educator intervention will have a greater reduction in the frequency of risk behaviors. Similar effects are expected for network members of intervention participants.

Description:

The investigators will recruit male Tajik migrants who inject drugs from 12 different sites in Moscow, including bazaars and other work sites. In both study arms, the recruited men (index participants) will be required to recruit two eligible MWID peers for interviews prior to being interviewed themselves. Participants will be randomly assigned to either the peer educator intervention program or the health education intervention program. After peer-recruited network members are enrolled and interviewed, the index participant will participate in the peer educator training or the control group activities. All participants and recruited network members will then be followed and re-interviewed at 3-month intervals for one year to assess changes in risky drug, alcohol, and sexual behaviors due to intervention participation and through diffusion to network members. The investigators will also collect data from voluntary HIV and HCV testing conducted at 6 months (HCV only) and at 12 months (HIV and HCV) post-intervention.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 420
• Est. completion date: May 28, 2023
• Est. primary completion date: May 4, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• adult Tajik man

• injected drugs in past 30 days

• living and working as migrant laborer in Moscow

Exclusion Criteria:

• does not intend to stay in Moscow for the next 12 months

Related Conditions & MeSH terms

• Hepatitis C
• HIV Infections
• Risk Reduction Behavior
• Risky Health Behavior

Intervention

Behavioral:
• MASLIHAT
peer educator intervention
• TANSIHAT
health education intervention

Locations

Country	Name	City	State
Russian Federation	PRISMA Research Center	Moscow

Sponsors (3)

Lead Sponsor	Collaborator
University of Illinois at Chicago	National Institute on Drug Abuse (NIDA), Prisma Research Center

Country where clinical trial is conducted

Russian Federation, 

References & Publications (2)

Luc CM, Levy J, Bahromov M, Jonbekov J, Mackesy-Amiti ME. HIV knowledge, self-perception of HIV risk, and sexual risk behaviors among male Tajik labor migrants who inject drugs in Moscow. BMC Public Health. 2024 Jan 11;24(1):156. doi: 10.1186/s12889-023-17543-1. — View Citation

Mackesy-Amiti ME, Levy JA, Bahromov M, Jonbekov J, Luc CM. HIV and Hepatitis C Risk among Tajik Migrant Workers Who Inject Drugs in Moscow. Int J Environ Res Public Health. 2023 May 24;20(11):5937. doi: 10.3390/ijerph20115937. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	injection equipment sharing	frequency of using shared injection equipment	3 months
Primary	syringe sharing	frequency of injecting with a previously used syringe	3 months
Primary	sex without condom	frequency of vaginal or anal sex without a condom in the past 3 months	3 months
Primary	alcohol use	Number of days drinking alcohol in past month	30 days
Secondary	HIV infection	incident HIV infection	12 months
Secondary	hepatitis C infection	incident HCV infection	12 months