HIV Infections Clinical Trial
Official title:
Possible Changes in HIV Drug Resistance Pattern Due to Migration of People From the Eastern Europe to Poland
According to the Polish governmental statistics migration of people from Ukraine to Poland is growing and only in year 2020 have come to Poland about a quarter of a million of Ukrainian migrants. As well, more than 40% of those diagnosed with HIV infection in the European Union (EU)/European Economic Area (EEA) in 2018 were also migrants, originating from countries with generalized HIV epidemics, such as Ukraine. Antiretroviral treatment should be started, based, among others, on epidemiological data and evidence of presence of drug resistance mutations in a the population.
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | June 30, 2023 |
Est. primary completion date | December 31, 2022 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - recent diagnosis with HIV infection (<6 months) - no history of antiretrovirals intake (PrEP, PEP) - age 18 years or olde Exclusion Criteria: - failure to meet any of the inclusion criteria |
Country | Name | City | State |
---|---|---|---|
Poland | Department of Infectious Diseases, Tropical Diseases and Hepatology, Medical University of Warsaw | Warsaw | Mazowia |
Lead Sponsor | Collaborator |
---|---|
Medical University of Warsaw |
Poland,
Shafer RW, Rhee SY, Pillay D, Miller V, Sandstrom P, Schapiro JM, Kuritzkes DR, Bennett D. HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance. AIDS. 2007 Jan 11;21(2):215-23. Review. — View Citation
Wensing AM, Calvez V, Ceccherini-Silberstein F, Charpentier C, Günthard HF, Paredes R, Shafer RW, Richman DD. 2019 update of the drug resistance mutations in HIV-1. Top Antivir Med. 2019 Sep;27(3):111-121. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Difference in HIV drug resistance pattern | Differences between people originating from Poland and from Eastern Europe | 2 years |
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