HIV Infections Clinical Trial
Official title:
Short-term Effectiveness of a Community Health Worker Intervention for HIV-infected Pregnant Women in Tanzania to Improve Treatment Adherence and Retention in Care: A Cluster-Randomized Trial
The investigators implemented and evaluated a pilot program in Shinyanga Region, Tanzania to
bring prevention of HIV services to communities using community health workers (CHWs). The
intervention aimed to integrate community-based maternal and child health services with HIV
prevention, treatment, and care—bridging the gap between women and facility, and enhancing
the potential benefits of Option B+. Option B+ is the current World Health Organization
recommendation for prevention of mother-to-child transmission, but its success in
sub-Saharan Africa may be threatened by overburdened clinics and staff. Consequently,
paraprofessionals like CHWs can be key partners in the delivery and/or enhancement of health
services in the community.
The study focuses on whether this approach: increases retention in care; improves adherence
to antiretrovirals (ARVs); or improves the number of women initiating antiretroviral therapy
and the timing of initiation. Investigators hypothesize improvements along primary and
secondary outcome indicators in the treatment group. This evaluation helps illuminate both
the impact and feasibility of the intervention, and the role that CHWs may play in the
elimination of mother-to-child transmission services.
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