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Heart Diseases clinical trials

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NCT ID: NCT05717049 Completed - Clinical trials for Congenital Heart Disease

Theophylline Effects in the Fontan Circulation

THIEF
Start date: February 9, 2023
Phase: Phase 2
Study type: Interventional

A single group treatment phase 2 single-arm no-masking study to assess safety and efficacy of a short-term oral treatment with theophylline (ATC-no. R03D A04) in terms of improvements in cardiorespiratory fitness, health-related quality of life, cardiac performance and respiratory function in male and female adolescents aged 16 to 25 years with a Fontan-type surgical palliation of univentricular congenital heart disease.

NCT ID: NCT05715879 Completed - COVID-19 Pandemic Clinical Trials

Covid-19 Infection and Long-term Cardiovascular Symptoms

Start date: October 1, 2020
Phase:
Study type: Observational [Patient Registry]

From the registry of professor Kojuri clinic , those with Covid-19 infection were selected and was contacted and asked about the cardiovascular symptoms, 1 year after the covid infection

NCT ID: NCT05712226 Completed - Hypertension Clinical Trials

Sleepiz One+ Versus Capnography and Electrocardiography

SPZCAP
Start date: February 22, 2023
Phase: N/A
Study type: Interventional

EtCO2, or exhaled carbon dioxide, is a non-invasive and commonly used measure for respiratory rate and function. It can be easily monitored using a device called a capnograph, which consists of a sensor that is placed near the patient's mouth or nose and a monitor that displays the concentration of carbon dioxide in the respiratory gases in real-time. EtCO2 capnography is generally considered a reliable and accurate method for monitoring respiration and is often used as a gold standard for comparing the performance of other methods for measuring respiration. Therefore, the primary aim of this study is to provide a thorough comparison of the performance of Sleepiz One+ and EtCO2 Capnography for measuring respiration rate, in healthy adults and patients suffering from chronic conditions (e.g. hypertension, COPD, asthma, diabetes), at rest in a clinical setting. Additionally, the performance of heart rate estimation will be evaluated against ECG.

NCT ID: NCT05710302 Completed - Heart Failure Clinical Trials

Prospective Validation of the Emergency Heart Failure Mortality Risk Grade (EHMRG) Score in Patients With Acute Heart Failure in the Emergency Department

Start date: July 29, 2022
Phase:
Study type: Observational

In this prospective validation study, researchers investigates accuracy of EHMRG (Emergency Heart Failure Mortality Risk Grade) score in predicting the 7th and 30th day risk of mortality in patients with acute heart failure who applying to the emergency department.

NCT ID: NCT05708690 Completed - Clinical trials for Coronary Artery Disease

Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery

Start date: October 1, 2022
Phase: Phase 4
Study type: Interventional

This is a single-center, double-blind, randomized controlled trial (RCT) comparing two groups of application of topical dose of tranexamic acid (TxA) versus placebo in patients undergoing coronary artery bypass graft (CABG), off pump coronary bypass graft cardiac surgery (OPCAB), and adult heart valve surgery. The primary outcomes of this study comprised of two parameters; post operative bleeding and blood product transfusion. The primary outcomes were assessed during the operation, until 48-hour post operative.

NCT ID: NCT05706805 Completed - Clinical trials for Coronary Artery Disease

NAVISCORE PMCF Study ( rEPIC04F )

rEPIC04F
Start date: January 31, 2023
Phase:
Study type: Observational

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Naviscore scoring balloon to meet EU Medical Device regulation (MDR) requirements in all the CONSECUTIVE patients treated with Naviscore.

NCT ID: NCT05704946 Completed - Nursing Caries Clinical Trials

The Effect of Lavender Inhalation on Sleep Quality in Individuals With Coronary Heart Disease

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The study is planned to be conducted as a two-group randomized controlled trial to determine the effect of lavender inhalation on individuals with coronary heart disease. Research data will be collected at Çukurova University Medical Faculty Balcalı Hospital Cardiology Clinic between January-June 2023. In the study, at least 56 samples were found to be sufficient for the sample size. The data of the study will be collected using the Personal Information Form and the Pittsburg Sleep Quality Index.

NCT ID: NCT05698121 Completed - Cardiac Disease Clinical Trials

Evaluation of a Preparatory eHealth Intervention to Support Cardiac Patients During Their Waiting Period.

PReCARE
Start date: February 8, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot study is to evaluate the feasibility of an eHealth intervention for cardiac patients during their waiting period before their rehabilitation. The main questions it aims to answer are: - What is the feasibility of an eHealth intervention designed for cardiac patients with a low socio-economic position during the waiting period before their cardiac rehabilitation. - What is the potential effect of this intervention on patient activation and feelings of certainty and guidance. Participants will: - Be randomised in either intervention or control group - Fill in a questionnaire at the start of their waiting period (after release from the hospital) - Use the eHealth intervention during their waiting period (usually 2 to 6 weeks)(intervention group only) - Fill in a questionnaire at the start of their rehabilitation Researchers will compare intervention and control group to see if the intervention has improved patient activation and feelings of certainty and guidance.

NCT ID: NCT05693428 Completed - Clinical trials for CHD - Coronary Heart Disease

Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults

Start date: January 22, 2022
Phase: N/A
Study type: Interventional

Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment. Given the potentially preventable nature of a number of these postoperative complications, preventive methods should be used to improve outcomes after cardiac surgery. One of them, is the choice of anaesthetic technique. Objectives: To evaluate the effects of sevoflurane, isoflurane and propofol on blood oxygen transport function and body energy expenditure during cardiac surgery in adults. Materials and methods. A total of 90 patients were included in the study. All patients were divided into 3 groups: 1- (n=30) included patients who were anesthetized with propofol. The second group (n=30) consisted of patients who underwent sevoflurane inhalation anaesthesia. Group 3 (n=30) was treated with isoflurane. All patients underwent coronary artery bypass grafting under cardiopulmonary bypass.

NCT ID: NCT05668611 Completed - Clinical trials for Rheumatic Heart Disease

Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System

ADD-RHD 2B
Start date: January 3, 2023
Phase: N/A
Study type: Interventional

The first primary objective of this study is to determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by expert trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease. The second primary objective is to determine the diagnostic performance (sensitivity and specificity) of secondary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by MOH nurse trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease.