The Complex Regional Pain Syndrome (CRPS) is a Chronic Pain Condition. This is a Preliminary Study to Explore and Test Clinical Hypothesis. They Suppose That CRPS Patients Have Impairment in Their Mental or Motor Imagery Abilities.

Healthy Clinical Trial

— ImagNimes  

Official title:

Pilot Study on the Assessment of Motor Imaging Skills in Patients With Complex Regional Pain Syndrome (CRPS)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04703348
• Other study ID #: LOCAL/2020/MO-01
• Status: Completed
• Phase: N/A
• Start date: January 12, 2021
• Est. completion date: October 16, 2022

Study information

• Verified date: November 2022
• Source: Centre Hospitalier Universitaire de Nimes
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Medical functional imagery seems to demonstrate that patients suffering from complex regional pain syndrome (CRPS) have cortical modifications that alter their motor (or mental) imagery capacities. Nowadays, the use of motor imagery exercises are used in conventional rehabilitation treatments. But, in clinical practice, no study has verified if patients with CRPS desmonstrate problems in their motor imagery capacities. The MIQ-RS (Motor Imagery Questionnaire - Revised Second) is a valid, reliable and translated into French questionnaire to measure patients' capacities to do mental imagery. In this study, we compare 3 groups of 50 patients : healthy patients, patients with CRPS and patients with musculoskeletal disorder without CRPS. Every patient will take the MIQ-RS for the right and left body side. We hypothesis that patients with CRPS have more deficit than the 2 others to realise motor imagery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 129
• Est. completion date: October 16, 2022
• Est. primary completion date: October 16, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient with French healthcare affiliation

• Adult patient (> 18 years old)

• Patient with bachelor degree minimum

• Patient practicing less than 150 minutes of moderate to intense physical activity per week

Specific Inclusion Criteria for CRPS group :

• Patient followed in the Evaluation and Treatment pain center (University Hospital of Nimes)

• Patient with secondary CRPS due to a traumatism or a surgery

Specific Inclusion Criteria for Musculoskeletal group :

• Patient with musculoskelettal disorder on a limb (upper or lower)

• Patient followed in the University Hospital of Nimes

Non inclusion Criteria :

• Patient who participates in another category 1 research

• Patient in a exclusion period in another study

• Patient under legal protection, under guardianship or under curatorship

• Patient for whom it is impossible to give clear information.

• Pregnant, parturient or breastfeeding patient.

• Patient with amputation on one of his limb

• Patient with visual cecity

• Patient who has already practiced mental imagery

• Patient with neurological impairment

• Patient with chronic low back pain and fibromyalgia

Specific non inclusion criteria for Musculoskeletal group and healthy group :

-Patient with CRPS

Specific non inclusion Criteria for CRPS group :

• Secondary CRPS to CVA (cerebrovascular accident)

• Patient receiving lymph node block treatment between the inclusion visit and the follow-up visit

Specific non inclusion Criteria for Musculoskeletal Disorder group :

• Patient with secondary musculoskeletal disorder to a CVA

Exclusion criteria :

• Questionnaire MIQ-RS not completed or non respect with the research protocol

• pathology discovered incompatible with the study criteria

Related Conditions & MeSH terms

• Collagen Diseases
• Complex Regional Pain Syndromes
• Healthy
• Musculoskeletal Pain
• Musculoskeletal Pain Disorder
• Reflex Sympathetic Dystrophy
• Rheumatic Diseases
• Somatoform Disorders
• Syndrome

Intervention

Diagnostic Test:
• Motor imagery Questionnaire - Revised Second (MIQ-RS)
Patients fulfill a questionnaire measuring individuals capacities to realize mental imagery. For more facilities and less risk of bias, the MIQ-RS was written on an online version with questions recorded in audio format. No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery a score between 49 and 73/98 have disturbed motor imagery capacities a score more than 74/98 have normal motor imagery capacities.

Locations

Country	Name	City	State
France	CHU de Nimes	Nimes	Gard

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nimes

Country where clinical trial is conducted

France, 

References & Publications (44)

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* Note: There are 44 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Motor imagery capacities on the affected side for CRPS group and musculoskelettal disorder group.	Taking the MIQ-RS for 1 side, during about 20 minutes The questionnaire includes 14 questions : 7 for kinesthesic motor imagery and 7 for visual motor imagery For less bias, the questionnaire was recorded in audio for each of the 14 questions on an online assessment.; No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery; a score between 49 and 73/98 have disturbed motor imagery capacities; a score more than 74/98 have normal motor imagery capacities.	Day 1
Secondary	Motor imagery capacities between affected side and unaffected side	Taking the MIQ-RS for 1 side, during about 20 minutes The questionnaire includes 14 questions : 7 for kinesthesic motor imagery and 7 for visual motor imagery For less bias, the questionnaire was recorded in audio for each of the 14 questions on an online assessment.; No official cut-off exists but studies seem to prove that people with : a score less than 48/98 are unable to do motor imagery; a score between 49 and 73/98 have disturbed motor imagery capacities; a score more than 74/98 have normal motor imagery capacities.	Day 1

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