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Gingival Recession clinical trials

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NCT ID: NCT06006780 Recruiting - Gingival Recession Clinical Trials

Porcine Acellular Dermal Matrix for the Treatment of Localized Gingival Recessions A Multicenter Randomized Clinical Trial.

Start date: September 10, 2022
Phase: N/A
Study type: Interventional

Aim: The aim of this randomized clinical trial is to evaluate the use of the porcine acellular dermal matrix (PADM) for the treatment of RT1 localized gingival recessions. Material and methods: Forthy patients (n=20) with RT1 localized gingival recessions with height ranging from 3 to 5 mm with and at least, 2mm of keratinized tissue width will be selected to participate in the study. Patients will be allocated randomly in two treatment groups: Coronally advanced flap (CAF) or coronally advanced flap associated with the porcine acellular dermal matrix (CAF+ PADM). The clinical parameters evaluated at the baseline, 6 and 12 months will be: Plaque index (IPL); gingival index (GI); relative gingival recession height (RGRH); gingival recession width (GRW); probing depth (PD); relative clinical attachment level (RCAL); keratinized tissue height (KTH); keratinized tissue thickness (KTT); papilla height (PH). Evaluations will be made by the professional and the patient regarding dentin hypersensitivity (HD) (Schiff and VAS scales respectively), aesthetics (RES and VAS scales, respectively) and patient's centered outcomes, through the questionnaire referring to the OHIP-14. Descriptive statistical analysis will be expressed as mean ± standard deviation (SD), median, quartiles, percentages and confidence intervals (95% CI). To analyze the normality of the residue, the Shapiro-Wilk test will be performed. Then, the Wilcoxon test will be applied to compare the periodontal parameters and a quality of life, before and post-treatment. Correlations between parameters and dental hypersensitivity will be analyzed through Spearman's test. Key words: Gingival recession, Root coverage, Biomaterial, Acellular dermal matrix.

NCT ID: NCT06000228 Recruiting - Clinical trials for Gingival Recession, Localized

Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

Aim of this study is to assess the influence of vestibular depth on root coverage in Miller class III/ Cairo RT2 gingival recession when treated with minimally invasive technique using connective tissue graft.

NCT ID: NCT05990049 Recruiting - Pain, Postoperative Clinical Trials

Hyaluronic Acid and Free Gingival Graft Healing

Start date: March 1, 2023
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the impact of locally applied hyaluronic acid on free gingival graft wound bed healing and palatal donor site wound healing. Forty subjects will be randomly divided in two separate groups. Test group will be treated with hyaluronic acid during the procedure and the control group without. Periodontal parameters and other clinical measurements will be taken on baseline, 7 days postoperative, 14 days postoperative, 1 month, 3 months and 6 months postoperative.

NCT ID: NCT05976451 Completed - Clinical trials for Gingival Recession Types One(RT1)

Time Effect on the Predictability of Different Grafting for Gingival Recession RT 1

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The primary objective of this study was to evaluate time effect on the clinical predictability of collagen matrix Xenograft (CMX) with melatonin gel versus connective tissue graft (CTG) and determine whether it is proposed to be an alternative in multiple adjacent gingival recession (MAGR) in recession type one (RT1)

NCT ID: NCT05961566 Recruiting - Recession, Gingival Clinical Trials

Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate. The main questions it aims to answer are: - Are there tissue thickness changes between the two groups (control group and augmentation group)? - Are there volumetric changes in the donor site (palate) between the two groups in the short and long term? Participants will receive a gum graft and then based on what group they were randomly assigned, they will receive either a collagen matrix where the gum graft was taken (on the palate) or nothing will be placed. Researchers will compare non-augmented sites with augmented sites to see if there is a change in tissue thickness and volume.

NCT ID: NCT05956496 Terminated - Gingival Recession Clinical Trials

Gingival Augmentation and Root Coverage With Superficial and Deep Cut Acellular Dermal Matrices

Start date: October 3, 2023
Phase: N/A
Study type: Interventional

This entire protocol involves procedures that are standard care and will randomize subjects to of one two routine care procedures. Patients needing root coverage for gingival recession will be enrolled.

NCT ID: NCT05949112 Not yet recruiting - Recession, Gingival Clinical Trials

Toothbrush in the Genesis and Prevention of Dental Recessions

Recession
Start date: July 27, 2023
Phase: N/A
Study type: Interventional

The aim of this research is to evaluate the effect of brushing on gingival recessions and to understand the impact of manual brushing and brushing with mechanical aid on their evolution. The study involves the recruitment of 90 patients with or without gingival recessions at the Dentistry service of the University of Genoa. The first phase involves the evaluation of the brushing force on the genesis of gingival recessions. A questionnaire will be filled out and the same toothbrushes and toothpastes will be provided for one month to 30 patients with recessions and 30 patients without recessions. After a month, the "wear" of the manual toothbrush and the gingival health indices will be measured. In this phase 60 patients with recessions will be divided into two groups according to the oral hygiene method that will be recommended. In the first group a super soft toothbrush will be delivered, in the second group a mechanical toothbrush. Gingival health indices will be taken and an intraoral scan will be done to measure recessions. At 6 months and 12 months the indices will be measured again and compared between the two groups. This research has two objectives: 1. Evaluate the differences in wear of the manual toothbrush head after one month of use between patients with gum recession and patients without gum recession. In the case of greater wear among patients with recessions it could be assumed that a greater brushing force is able to determine the formation of recessions. 2. Try to understand if there are differences between the super soft manual toothbrush and the mechanical toothbrush regarding the effectiveness of use and the "delicacy" on recession. Both tools are currently recommended for patients with recessions, but there are no studies in the literature comparing the two tools.

NCT ID: NCT05949073 Recruiting - Gingival Recession Clinical Trials

The Impact of Retraction Cords on the Gingival Margin Level.

Start date: July 25, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the relationship between placing specific retraction cord for different periods of time and the post-operative gingival margin level in humans. Determining the amount of immediate reversible and delayed irreversible gingival recession (vertical gingival retraction) that might happen after placing a retraction cord around a natural tooth in healthy humans. It also aims to investigate the impact of mechanical and chemo-mechanical gingival retraction on periodontal health.

NCT ID: NCT05947305 Enrolling by invitation - Wound Heal Clinical Trials

Alternative Gingival De-Epithelialization Techniques

Start date: April 4, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare different de-epithelialization methods in patients undergoing soft tissue augmentation surgery. The main questions it aims to answer are: • Which technique is superior for de-epithelialization in terms of remaining epithelium, wound healing of the donor site, and clinical outcomes?

NCT ID: NCT05923294 Recruiting - Clinical trials for Gingival Recession, Localized

Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in localized recessions of anterior and premolar teeth. In addition, it is aimed to compare the postoperative gingival thickness between the two techniques. The secondary aim is to search the effects of both techniques on periodontal parameters and to evaluate patient-centered outcomes.