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Gingival Recession clinical trials

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NCT ID: NCT06330662 Enrolling by invitation - Gingival Recession Clinical Trials

Effectiveness of Hyaluronic Acid on Multiple Adjacent Gingival Recessions Using a Coronally Advanced Flap

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical randomized trial is to examine the effectiveness of hyaluronic acid in treatment of multiple adjacent gingival recessions in 2 groups. Control group will be presented by using a coronally advanced flap only (CAF) and experimental group will be presented with addition of hyaluronic acid to a coronally advanced flap (CAF+HA). The main question it aims to answer is: is there any difference in the reduction of multiple gingival recessions between the control (CAF) and the test group (CAF + HA)? The research would be conducted on subjects referred for specialist treatment at the Department of Periodontology (Faculty of dental medicine, University of Zagreb). A record would be kept of all patients who underwent a detailed clinical examination, those who did not meet the criteria for inclusion in the study and those who refused to participate in it. Participants who meet the inclusion criteria will undergo a detailed clinical examination and if they agree to participate in the research, they will sign the informed form. During the pre-treatment, patients will receive instructions and a demonstration on proper maintenance of oral hygiene as well as a teeth cleaning. In addition to the informed form, they will fill out the OHIP-14 questionnaire, and the researcher will measure the periodontal indices at the very beginning before the operation, as well as the Schiff index. Patients will be photographed at the baseline as well as at follow-up examinations. The total number of subjects would be 42, or 21 patients in the 2 observed groups. The control group refers to surgical intervention using a coronally advanced flap to cover multiple gingival recessions without the addition of hyaluronic acid (CAF) and the experimental group indicates the surgical intervention using a coronally advanced flap to cover multiple adjacent gingival recessions with the addition of hyaluronic acid intraoperatively (CAF + HA).

NCT ID: NCT06065774 Enrolling by invitation - Clinical trials for Gingival Recession, Localized

Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial

Start date: July 17, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare two different tunneling surgical technique in treatment of gingival recession using two different materials. Participants will be divided into four groups according to the treatments they'll be given.

NCT ID: NCT05947305 Enrolling by invitation - Wound Heal Clinical Trials

Alternative Gingival De-Epithelialization Techniques

Start date: April 8, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare different de-epithelialization methods in patients undergoing soft tissue augmentation surgery. The main questions it aims to answer are: • Which technique is superior for de-epithelialization in terms of remaining epithelium, wound healing of the donor site, and clinical outcomes?

NCT ID: NCT05591326 Enrolling by invitation - Gingival Recession Clinical Trials

The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients With Gingival Recession.

Start date: September 6, 2021
Phase: N/A
Study type: Interventional

Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction. Platelet-rich fibrin (PRF) has been routinely used for more than 20 years to increase keratinized gingival thickness and to close gingival recessions due to the growth factors it contains. In the literature, there are studies evaluating the application of i-PRF with the microneedling technique, but there is no study evaluating the creeping attachment phenomenon and the closure percentage of gingival recession with the creeping attachment after the application of this technique. The aim of this study is to evaluate the closure rates of gingival recession and creeping attachment phenomenon after i-PRF application with microneedling technique. Systemically healthy and non-smoker patients older than 18 years of age with gingival recession in mandibular anterior teeth and keratinized gingival deficiency will be included. Before the procedure, the venous blood taken from the patient will be centrifuged at 700 RPM for 3 minutes in glass and non-addition tubes to obtain i-PRF. The prepared i-PRF will be infected to the apical mucogingival junction of the keratinized gingival area. This process will be repeated once a month for 3 months. After the 3rd month, the horizontal and vertical gingival recession values will be evaluated and recorded at the end of 6 months and 1 year.

NCT ID: NCT05389059 Enrolling by invitation - Gingival Diseases Clinical Trials

Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

This study is proposing the use of i-PRF clot as a scaffold for the XCM in order to obtain a novel biomaterial, incorporating active growth factors and collagen matrix in a single framework, based on the potential effect of i-PRF to enhance fibroblast activity and angiogenesis stimulation for treatment of multiple gingival recession.

NCT ID: NCT04202198 Enrolling by invitation - Recession, Gingival Clinical Trials

Pinhole Surgical Technique for Root Coverage Using PRF

Start date: November 22, 2019
Phase: Phase 2
Study type: Interventional

The current study is a prospective randomised split mouth study to evaluate the effect of Platelet Rich Fibrin as an adjunct to the minimally invasive pinhole surgical technique.

NCT ID: NCT03660566 Enrolling by invitation - Tooth Loss Clinical Trials

Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant

Start date: August 10, 2018
Phase: N/A
Study type: Interventional

The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF) membranes. The sample is of 42 individuals, where the control group (n = 21) will receive single implant placement only, while the test group will receive single implant placement with L-PRF membranes.

NCT ID: NCT02742493 Enrolling by invitation - Gingival Recession Clinical Trials

RCT for the Effectiveness of 3 Orthodontic Retention Schemes on Post-treatment Stability and Gingival Recession

OrthRe10tion
Start date: April 2016
Phase: N/A
Study type: Interventional

The present study aims to assess the effectiveness of three different retention schemes used to maintain tooth position after orthodontic treatment with fixed orthodontic appliances (stability) and to evaluate possible association between retention scheme and gingival recessions on the lingual surfaces of the lower anterior teeth seen for up to 5 years post-treatment. Moreover the possible association between primary relapse tendency and long term occlusal stability will be evaluated.

NCT ID: NCT01814592 Enrolling by invitation - Gingival Recession Clinical Trials

Comparison Between Two Coronally Positioned Flap With Connective Tissue

Start date: March 2013
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effectiveness of total root coverage between two coronally positioned flap technique in Miller recession Class I and II, in patients attending at "Universidad El Bosque" dental school clinics.