Clinical Trials Logo

Gingival Recession clinical trials

View clinical trials related to Gingival Recession.

Filter by:

NCT ID: NCT01440426 Completed - Gingival Recession Clinical Trials

Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects

Start date: September 2011
Phase: Phase 4
Study type: Interventional

This study deals with coverage of multiple denuded roots. The current standard treatment requires surgical correction and uses soft tissue taken from the roof of the mouth to enhance results. The hypothesis of this trial is that a synthetic collagen matrix (called Mucograft) can be used to replace soft tissue taken from the subject. If the collagen matrix will prove to be equally as effective as the patient own tissue, it will be possible to avoid a more extensive surgery and decrease pain and discomfort.

NCT ID: NCT01175720 Completed - Gingival Recession Clinical Trials

Clinical Comparison Between Two Surgical Techniques for the Treatment of Gingival Recessions

Start date: August 2010
Phase: N/A
Study type: Interventional

The aim of this study is to test a surgical technique for the treatment of gingival recessions. The hypothesis of the study is to promote greater root coverage and better healing.

NCT ID: NCT01143610 Completed - Gingival Recession Clinical Trials

A New Therapeutic Approach for Root Coverage

Start date: February 2008
Phase: N/A
Study type: Interventional

Different surgical techniques have been proposed for root coverage, showing varying results especially in areas of deep recessions. The aim of this study is to evaluate the effectiveness of the newly forming bone technique (NFB)as an alternative treatment for Miller class I or II deep recessions, requiring regeneration of lost periodontal tissues. Sample should be comprised of patients aged 18-45 years, both genders, presenting at least one site with marginal tissue recession >4mm. Patients will be randomly assigned to either one of the groups, based on treatment technique: newly forming bone (NFB) or subepithelial connective tissue graft (SCTG). Clinical examinations will be performed by a single blinded examiner at baseline, 1, 3, 6 and 9 months after surgery. Intra-group analysis will be performed by one way analysis of variance for repeated measures. Inter-group analysis will be performed by unpaired t-test for each of evaluation periods.

NCT ID: NCT01134081 Completed - Gingival Recession Clinical Trials

Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this research study is to understand more about wound healing of gum tissue. Fluids collected from between a tooth and the gum and directly from wounds contain proteins that occur in different levels as the wound healing process proceeds. In this research study wound fluid will be collected from the donor palate site (roof of your mouth) and the treated sites on your gum before and after placement of CelTx or conventional treatment (tissue from the roof of your mouth) to measure which proteins and how much of each are present during the first 4 weeks of wound healing.

NCT ID: NCT00902876 Completed - Gingival Recession Clinical Trials

A Randomized Controlled Clinical Trial to Evaluate Safety and Effectiveness of CAF + Mucograft® Compared to CAF Alone in Patients With Gingival Recessions

MCT-Recession
Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this multi-center study is to determine the efficacy and safety of Mucograft® in combination with the coronally advanced flap (CAF) for the treatment of gingival recessions. It is assumed that the CAF combined with Mucograft® will result in improved outcome in terms percentage of root coverage and soft tissue thickness in comparison to CAF alone (control).

NCT ID: NCT00881959 Completed - Gingival Recession Clinical Trials

Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®

Start date: August 2009
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate whether clinical parameters for Puros Dermis are, at minimum, equivalent when compared to AlloDerm, the current industry standard, for the treatment of single, non-adjacent Miller's Class I or II gingival recession.

NCT ID: NCT00720707 Completed - Gingival Recession Clinical Trials

Coronally Advanced Flap in Combination With Acellular Dermal Matrix and Enamel Matrix Derivatives for Root Coverage

Start date: April 2006
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the clinical outcomes of root coverage procedures, using coronally advanced flap in combination with acellular dermal matrix with or without enamel matrix derivatives .

NCT ID: NCT00679081 Terminated - Gingival Recession Clinical Trials

A Pilot Study of CelTx(TM) (Apligraf®) in the Treatment of Gingival Recession Requiring Root Coverage

Start date: May 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate CelTx as an alternative to tissue from the palate in the treatment of subjects with Miller Class I or II recession defects who desire root coverage. It is anticipated that this study will demonstrate that CelTx is a safe alternative to palatal tissue and demonstrate potential to enhance oral soft tissue regeneration and wound healing.

NCT ID: NCT00587834 Completed - Gingival Recession Clinical Trials

Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration

Start date: October 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate Gintuit as a safe and effective alternative to palatal tissue in the treatment of subjects (with recession-type defects) who have an insufficient zone of attached gingiva associated with at least two nonadjacent teeth.