Genetic Predisposition Clinical Trial
Official title:
Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football
Verified date | January 2022 |
Source | St Mary's University College |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury. This score was then compared with the incidence of injury between those with high, medium and low risk scores for each injury. The influence of different rates of growth, stages of physical maturation and loading exposure were then also included in the risk model to see if any interaction effects could be observed between genetic risk score and susceptibility to injury in different categories of growth, maturation and loading exposure.
Status | Completed |
Enrollment | 95 |
Est. completion date | July 31, 2021 |
Est. primary completion date | July 31, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 12 Years to 40 Years |
Eligibility | Inclusion Criteria: - Elite male football players Exclusion Criteria: - Female - non-elite |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Fulham Football Club | London | New Malden |
United Kingdom | St Mary's University, Twickenham | London | Twickenham |
Lead Sponsor | Collaborator |
---|---|
St Mary's University College | Fulham Football Club |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fracture Injury Risk | Did the risk of fracture differ between total genotype risk score categories? was this affected by maturation? | 8 Years | |
Primary | Non-Contact Injury Risk | Did the risk of non-contact injury differ between total genotype risk score categories? was this affected by maturation, and loading? | 8 Years | |
Primary | Non-Contact Muscle Injury Risk | Did the risk of non-contact muscle injury differ between total genotype risk score categories? was this affected by maturation, and loading? | 8 Years | |
Primary | Tendon Injury Risk | Did the risk of tendon injury differ between total genotype risk score categories? was this affected by maturation, and loading? | 8 Years | |
Primary | Ligament Injury Risk | Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation? | 8 Years | |
Primary | Apophysitis Injury Risk | Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation? | 8 Years |
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