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Fractures, Bone clinical trials

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NCT ID: NCT03423043 Completed - Radius Fractures Clinical Trials

Low Dose CT Distal Radius Fractures

Start date: July 15, 2018
Phase:
Study type: Observational

This study is a prospective, departmental funded study examining the outcomes of Low Dose CT scans compared to Conventional Dose CT scans in patients who present to Duke University with a Distal Radius Fracture.

NCT ID: NCT03422497 Completed - Surgery Clinical Trials

The Association of Sex With Guideline-based Perioperative Care in Hip Fracture Surgery

Start date: May 2013
Phase: N/A
Study type: Observational

The investigators will use multilevel multivariable regression analysis to measure the association of sex with provision of guideline-based perioperative care for hip fracture surgery in Ontario.

NCT ID: NCT03419182 Completed - Acetabular Fracture Clinical Trials

RCT Determining Best Treatment for Geriatric Acetabular Fractures

GeriTab
Start date: April 13, 2011
Phase: N/A
Study type: Interventional

There is debate over the best management for acetabular (hip) fractures that occur within the geriatric population. Geriatric patients, 60 years or older, are at greater risk for operative complications because they tend to have poorer bone quality, complicated fractures, and multiple health problems. Physicians currently have no guidelines as to the best surgical management for these particular fractures, because there is little data on the long-term outcomes of these injuries. The use of internal fixation (a nail or plate) is a standard method for repairing these injuries, however when the injuries are complicated it is predicted to have a poorer outcome than performing internal fixation along with total hip arthroplasty (joint reconstruction). Given the significant problems that result from hip fractures in this population, our study is designed to determine the best method for treatment of acetabular fractures and to clarify the criteria for treatment with guidelines assisting the physician in selecting the appropriate treatment.

NCT ID: NCT03417310 Completed - Clinical trials for Femur Shaft Fracture

Clinical Applications of a Joystick in Femoral Shaft Fractures

Start date: April 1, 2015
Phase: N/A
Study type: Interventional

This study will use a new "H" joystick for reduction on patients with femur fractures to investigate the reduction time, operating time and bone healing status for the evaluation of the clinical application benefits of this joystick.

NCT ID: NCT03415958 Completed - Clinical trials for Malunion of Fracture of Clavicle

A Prospective Cohort of Displaced Adolescent Midshaft Clavicle Fractures

Start date: March 28, 2012
Phase: N/A
Study type: Observational

Outcomes for displaced midshaft clavicle fractures in adolescents are not defined. The current method of treatment for these fractures is non-operative management. There is recent Level 1 evidence in the adult literature to suggest that outcomes are superior when these fractures are managed surgically with open reduction and internal fixation.

NCT ID: NCT03414411 Completed - HIV Infections Clinical Trials

Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study

Start date: February 20, 2018
Phase:
Study type: Observational

The purpose of this study is to follow a cohort of HIV-infected adults who have alcohol and/or drug use to: 1) test the associations between alcohol (and illicit drugs and polypharmacy (multiple prescribed medications)) and falls (fractures secondarily), and whether frailty mediates these associations; and 2) test the associations between alcohol (and illicit drugs and polypharmacy) and utilization (emergency department use and hospitalization for falls and fractures), and whether frailty mediates them. To achieve the stated aims the investigators will expand (to 400) and continue to follow an existing prospective cohort (The Boston ARCH Cohort) of adults with HIV infection and a high prevalence of exposure to alcohol, other drugs, and polypharmacy. The Boston ARCH Cohort is a longitudinal cohort (1-3.5 years of follow-up) of 250 HIV-infected men and women with current substance dependence or ever injection drug use that have a spectrum of alcohol use.

NCT ID: NCT03410823 Active, not recruiting - Hip Fracture Clinical Trials

PUSH Plus Protein Pilot for Hip Fracture Patients

Start date: July 16, 2018
Phase: N/A
Study type: Interventional

Hip fracture is a common problem among older individuals. The goal of current standard of care after hip fracture is to achieve independent, household ambulation 2-3 months after surgery, yet decreased functional ability typically persists well beyond three months and many patients never resume independent ambulation outside the home. Previous research has established that one must be able to walk at least 300 meters (~330 yards) within 6 minutes to re-establish routine interactions in the community, such as going to the store or to church. In part, this is based on the average distance from handicapped parking spaces into most facilities. Activity and exercise are believed to be of benefit for reducing disability in older adults, yet the majority of older adults does not participate in regular exercise and is not active. This is especially true for older adults following hip fracture after they complete the usual rehabilitation program. This research study is being done to test a 16-week, multi-part exercise intervention for hip fracture patients that will be supervised by specially trained physical therapists (PTs). The exercise intervention uses a novel machine to provide strength and endurance training in the home. This has been shown in smaller studies to be safe and effective at increasing strength. The purpose of this small pilot study is to test whether adding a protein supplement to the exercise intervention leads to more improvements in a person's ability to walk in their own home and in the local community. With this knowledge, investigators hope to help a greater number of hip fracture patients enjoy a more complete recovery and improved overall health. In addition to providing important information on adherence, feasibility, and safety, this pilot study of hip fracture patients has the unique advantage of being able to compare data to two recently completed studies where participants received the PUSH intervention without protein supplementation.

NCT ID: NCT03409354 Completed - Stroke Clinical Trials

Tele-Rehabilitation Pilot Evaluation Study

Start date: May 15, 2018
Phase: N/A
Study type: Interventional

A proof of concept randomized controlled trial (RCT) only evaluated the National University of Singapore's (NUS) T-Rehab tele-rehabilitation (TR) system at a home setting where rehabilitation was provided on an individual level. The previous RCT was also limited to stroke patients. In addition to stroke, there are many other conditions (such as fractures, lower limb joint replacement, musculoskeletal conditions) require and benefit from rehabilitation. The primary aims of the pilot evaluation study are: (i) To document patient adherence to TR, compared to usual care (ii) To estimate the extent to which TR improves functional status, compared to usual care and (iii) To estimate the cost effectiveness of TR, compared to usual care in eight different health conditions in Singapore.

NCT ID: NCT03407573 Completed - Anemia Clinical Trials

Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur

RESULT-NOF
Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The investigator wishes to see if it is possible to undertake a study comparing blood transfusion at two different levels of anaemia to see which is best for patients. All patients that present to hospital with a broken hip will be able to take part in the study. If they become anaemic during their treatment they will be allocated to either be transfused when their blood count is less that 9 or less than 7. In all patients, we will measure heart damage with a blood test that is very sensitive. The investigator will also collect data on the incidence of heart attacks and other complications.

NCT ID: NCT03407131 Not yet recruiting - Clinical trials for Intertrochanteric Fractures

Internal Fixation or Joint Replacement Therapy for Aged Hip Fracture Patients

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of internal fixation or arthroplasty for hip fracture patients over 75 years of age with multiple medical complications through the operation time, intraoperative bleeding, time to start weight bearing activities and other indicators.