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Fistula clinical trials

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NCT ID: NCT03381365 Terminated - Fistula in Ano Clinical Trials

Efficacy of an Anorectal Fistula Plug With Sealing of the Internal Opening as a Treatment for Perianal Fistula

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The investigators aim to assess the efficacy of the Curaseal anal plug in patients with idiopathic uncomplicated fistulous tracts. Healing of the fistula tract will be assessed both clinically and radiologically with MR imaging.

NCT ID: NCT03366727 Completed - Clinical trials for Arteriovenous Fistula Stenosis

AcoArt III / Arterio-venous Fistula in China

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This trial is aimed to evaluate the safety and efficacy of DCB in treating AVF stenosis in chinese population.

NCT ID: NCT03365089 Recruiting - Clinical trials for Hemodialysis Access Failure

Collateral Ligation in Failing Fistulas

CLiFF
Start date: May 14, 2018
Phase: N/A
Study type: Interventional

Arteriovenous fistulas (AVFs) for hemodialysis often fail to become usable due to failure to mature (FTM). The most common cause is narrowing of the artery or vein (stenosis). Another potential cause is the presence of collateral or side branch veins that steal blood flow from the main fistula channel. Some believe that occluding these veins might help maturation of those failing AVFs. To evaluate if this actually works, patients with FTM will be randomly assigned to side branch vein ligation (or not), and rates of AVF maturation of the two groups will be compared.

NCT ID: NCT03355508 Recruiting - Clinical trials for Arterio-venous Fistula, Puncture, Chronic Desease

Impact of the Arteriovenous Fistula Puncture Technique On the Hemodialysis Session For Patient and Caregiver

Start date: September 29, 2017
Phase: N/A
Study type: Interventional

40000 patients are hemodialysis each year in France . In the case of chronic care, 78% of patients have an arteriovenous fistula. In order to perform the hemodialysis session, 2 techniques of puncture of the fistula are possible: - Bevel puncture upwards then flipping the needle - or puncture bevel down. At present, there is no consensus or study on the technique of puncture fistula which generates different professional practices.

NCT ID: NCT03349424 Completed - Pancreatic Fistula Clinical Trials

Somatostatin Prevent Post-operation Pancreatic Fistula in Intermediate Risk Patients After Pancreaticoduodenectomy

Start date: June 22, 2018
Phase: Phase 4
Study type: Interventional

This study is designed to assess the preventive effects of somatostatin on post-operation pancreatic fistula in intermediate risk patients after pancreaticoduodenectomy. Patients assigned into the treatment group will be continuous intravenous infusion with the somatostatin (Stilamin®) in addition to conventional treatments (including infection prevention, nutrition support and acid suppression therapy, etc.).The pancreatic fistula incidence will be monitored within 30 days after operation.

NCT ID: NCT03345511 Completed - Pain, Postoperative Clinical Trials

Ultrasound Guided Caudal Block for Benign Anal Surgery

Start date: November 1, 2015
Phase: N/A
Study type: Interventional

Interventional study that evaluate analgesia and side effects of Ultrasound guided Caudal block preoperatively in benign canal anal surgery

NCT ID: NCT03325582 Recruiting - Perianal Fistula Clinical Trials

MR Assessment of Perianal Crohn's Disease

MAP
Start date: April 21, 2017
Phase:
Study type: Observational

Perianal Crohn's disease (pCD) is the commonest form of fistulising Crohn's disease, with up to 38% of patients affected and with 30% of them experiencing recurring disease symptoms. Presence of fistula can lead to major morbidity due to cutaneous perianal abscess formation or drainage. To date, it is very difficult to quantify inflammation in patients with pCD due to the absence of reliable disease activity measurements. In addition to this, optimising therapies for pCD is quite challenging and may have a major impact on quality of life. Magnetic resonance imaging of pelvic is a standard examination for the anatomical evaluation of pCD which is significant in terms of surgical therapy and progress. The overall hypothesis is that newer MRI techniques such as magnetization transfer (MT), diffusion weighted image ( DWI) and dynamic contract enhancement (DCE) are better suited to measuring the inflammatory vs fibrotic burden in pCD. The aim of this project is to measure disease activity within pCD and luminal CD using MRI sequences before and after biological therapy

NCT ID: NCT03322488 Recruiting - Crohn Disease Clinical Trials

Fistulodesis Pilot Study for Closure of Perianal Fistulae

Start date: June 20, 2017
Phase: N/A
Study type: Interventional

In this pilot study a new surgical treatment approach for perianal fistulae, called Fistulodesis, is performed. The study aims to assess effectiveness, safety and tolerability of the Fistulodesis procedure. The investigators are aiming to include 20 patients with Crohn's disease and 20 patients without underlying Crohn's disease. It is an open label study with an anticipated duration from January 2017 to January 2020.

NCT ID: NCT03321266 Completed - Anorectal Fistula Clinical Trials

Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas

Start date: November 30, 2017
Phase:
Study type: Observational

The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for statistical analysis.

NCT ID: NCT03317821 Completed - Clinical trials for Dural Arteriovenous Fistula

PHIL Evaluation in the Endovascular Treatment of Intracranial Dural AVF

Start date: September 18, 2017
Phase:
Study type: Observational [Patient Registry]

The primary objective of this study is to demonstrate the safety and efficacy of the PHIL® liquid in endovascular treatment of dural arteriovenous fistula.