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Fistula clinical trials

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NCT ID: NCT06422845 Not yet recruiting - Clinical trials for Arteriovenous Fistula Stenosis

Peripheral Scoring Drug-coated Balloon in the Treatment of Hemodialysis Arteriovenous Fistula Stenosis

SCDB
Start date: June 2024
Phase: N/A
Study type: Interventional

This is a prospective, multi-center, single-arm target value clinical study to study the safety and effectiveness of Peripheral Scoring Drug-coated Balloon dilatation catheters in the treatment of hemodialysis arteriovenous fistula stenosis.

NCT ID: NCT06416111 Not yet recruiting - Clinical trials for Renal Disease, Chronic

Comparison of Infraclavicular Brachial Plexus Block and Local Anesthesia in Arteriovenous Fistula Surgeries and Their Effects on Tissue Oxygen Saturation

Start date: May 22, 2024
Phase: N/A
Study type: Interventional

In arteriovenous fistula surgery, the effect of infraclavicular brachial plexus block and local anesthesia on tissue oxygenation and the effect of primary patency of the AV fistula is intended to research.

NCT ID: NCT06406621 Not yet recruiting - Pilonidal Sinus Clinical Trials

Laser Hair Depilation Darker Skin Pilonidal Disease

Start date: March 2025
Phase: N/A
Study type: Interventional

Pilot randomized trial assessing the effectiveness of laser hair depilation on pilonidal disease recurrence in patients with darker skin color

NCT ID: NCT06391281 Not yet recruiting - Hemodialysis Clinical Trials

Effect of Fistula Training in Hemodialysis Patients

Start date: April 26, 2024
Phase: N/A
Study type: Interventional

It was planned to examine the effect of fistula-related education given to patients receiving hemodialysis treatment on their self-care behaviors. Nurse-led education about fistula for hemodialysis patients affects fistula self-care behaviors. Nurse-led training regarding fistula to hemodialysis patients does not affect fistula self-care behaviors.

NCT ID: NCT06336226 Not yet recruiting - Clinical trials for Arterio-venous Fistula

Brachio Basilic Arterio Venous Fistula One Stage vs Two Stage

Start date: May 2024
Phase: N/A
Study type: Interventional

The aim of this work was to compare primary failure rates and the primary functional patency of one-stage vs two stage brachiobasilic fistulas to compare the two surgical techniques .

NCT ID: NCT06335862 Not yet recruiting - Oesophageal Atresia Clinical Trials

Primary Posterior Tracheopexy Prevents Tracheal Collapse

PORTRAIT
Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Introduction: Children born with a blind-ending gullet (oesophagus), or Oesophageal Atresia (OA), need to undergo surgical correction in the first week of life. OA is often accompanied by a weakened windpipe (trachea), known as tracheomalacia (TM). TM entails that the windpipe collapses during expiration. Severe TM can cause respiratory symptoms, including frequent respiratory tract infections and blue spells, that can potentially lead to life-threatening events. In some patients, major secondary surgical treatment may be indicated. This surgical procedure involves widening the trachea (using sutures) to prevent collapse, known as secondary posterior tracheopexy (SPT). Prior to performing this SPT, complications and negative consequences of TM may have already occurred. This may be prevented by performing this procedure during the primary OA correction, called a primary posterior tracheopexy (PPT). The aim of this trial is to determine if a PPT can decrease - or prevent - tracheal collapse in newborns with OA and TM, compared to a wait-and-see policy (no-PPT). Methods: This is an international multicentre double-blind randomised controlled trial. Seventy eight children with OA type C will be included. Patients will be included after written parental informed consent. Half of the patients will be randomly allocated to the PPT-group and half to the no-PPT-group. The degree and location of TM are evaluated through preoperative, intraoperative and two postoperative videoscopic examinations of the trachea (tracheobronchoscopy). Whether TM symptoms occur is assessed during three routine follow-up consultations until the age of 6 months. The primary outcome is the degree of collapse of the tracheal wall during the intraoperative tracheobronchoscopy (after performing the PPT/no-PPT), measured in percentages. Risks and burden: Since OA correction with PPT (more recently implemented in centres of expertise) and without PPT (wait-and-see policy) are both accepted and safe treatment options, participating in the trial does not pose an increased risk or burden with regards to the treatment. Performing tracheobronchoscopies may pose a potential burden. However, a tracheobronchoscopy is a routine diagnostic procedure commonly used to safely assess the trachea. Complications of a tracheobronchoscopy are rare. Also, many of the tracheobronchoscopies are routinely performed as part of standard care for these patients, regardless of the trial.

NCT ID: NCT06303752 Not yet recruiting - Anal Fistula Clinical Trials

Tissue Therapy of Transsphincteric Anal Fistula

REP-PAF
Start date: May 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical study aims to evaluate the outcome of the treatment of complex perianal fistulas (PAF) by the combination of minimal surgical debridement with regenerative cellular therapeutics.

NCT ID: NCT06297343 Not yet recruiting - Renal Failure Clinical Trials

Study of the Risk of Ischaemia Following the Creation of an Arteriovenous Fistula

MODIFVASC
Start date: May 2024
Phase:
Study type: Observational

The purpose of this study is to identify functional vascular changes and clinical factors correlated with the occurrence of short- or medium-term hand ischaemia after arteriovenous fistula creation.

NCT ID: NCT06198400 Not yet recruiting - Pancreatic Fistula Clinical Trials

Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Main goal of this study is to evaluate the blood flow in a post resection pancreatic remnant after pancreaticoduodenectomy with use of indocyanine green fluorescence. If the hypothesis will be proven, evaluation of perfusion of the pancreatic remnant with indocyanine green could be used to estimate the increased risk of the development of pancreatic fistula.

NCT ID: NCT06141044 Not yet recruiting - Drainage Clinical Trials

Prophylactic Abdominal Drainage vs no Drainage After Distal Pancreatectomy

PANDREAS
Start date: January 2024
Phase: N/A
Study type: Interventional

Postoperative pancreatic fistula (POPF) is a major source of morbidity and mortality after pancreatic resection, especially after distal pancreatectomy (PD). Today, POPF remains one of the main causes of hospital length of stay and healthcare costs. Numerous surgical techniques have been tested to reduce its incidence without success, so the current standard for the management of POPF, and the avoidance of associated complications, is intraoperative drain placement. However, surgically placed drains are not without risk. In recent years many studies, mostly retrospective, have attempted to determine whether omission of prophylactic drainage is associated with increased morbidity. These studies suggest that patients may benefit from not having a drain placed. This evidence challenges standard practice and the debate of whether or not to place a drain after distal pancreatectomy remains open. The investigators designed a prospective multicentre randomised non-inferiority study to determine whether prophylactic intraoperative drainage is associated with a lower morbidity rate after distal pancreatectomy.