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Fistula clinical trials

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NCT ID: NCT03466515 Completed - Crohn Disease Clinical Trials

Stem Cells Treatment of Complex Crohn's Anal Fistula

fistula
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A pilot study to investigate the safety and feasibility of stem cells treatment of complex anal fistula in patients with Crohn's disease.

NCT ID: NCT03455881 Recruiting - Tracheal Stenosis Clinical Trials

Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients

TED
Start date: March 28, 2018
Phase:
Study type: Observational

The investigators propose a preliminary study performing exome sequencing on samples from patients and their biologically related family members with tracheal and esophageal birth defects (TED). The purpose of this study is to determine if patients diagnosed with TED and similar disorders carry distinct mutations that lead to predisposition. The investigators will use advanced, non-invasive magnetic resonance imaging (MRI) techniques to assess tracheal esophageal, lung, and cardiac morphology and function in Neonatal Intensive Care Unit (NICU) patients. MRI techniques is done exclusively if patient is clinically treated at primary study location and if patient has not yet had their initial esophageal repair.

NCT ID: NCT03449069 Completed - Crohn Disease Clinical Trials

Pediatric MSC-AFP Sub-study for Crohn's Fistula

Start date: July 23, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease. Autologous means these cells to coat the plug come from the patient.

NCT ID: NCT03419676 Completed - Pancreatic Fistula Clinical Trials

Use of Hemopatch as a Sealant at the Pancreaticojejunostomy After Pancreatoduodenectomy

Start date: May 1, 2018
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine the effect of the sealant patch Hemopatch, compared to current practice without any sealant, on the decrease of the postoperative pancreatic fistula on patients undergoing pancreatoduodenectomy for benign or malignant tumors or other benign process.

NCT ID: NCT03414060 Recruiting - Obstetric; Injury Clinical Trials

Feasibility of the Menstrual Cup for VVF

FMCVVF
Start date: August 8, 2016
Phase: N/A
Study type: Interventional

This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana. The repeated measures design utilizes a 2-hr pad test to compare urinary leakage with and without the insertable cup, a questionnaire on acceptability and perceived effect is administered and a clinical exam is completed. Subsequently, semi-structured interviews will be carried out with up to 24 additional women seeking treatment at a health facility in Ghana. Interviews will cover women's experiences of living with fistula, including strategies for coping with urinary incontinence and resulting stigma, as well as user acceptability to the intervention.

NCT ID: NCT03410914 Completed - Surgery Clinical Trials

Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy

PATCH-DP
Start date: August 13, 2018
Phase: Phase 2
Study type: Interventional

Despite improvements and advances in pancreas surgery, about 30-35% of patients who have pancreas surgery develop a type of complication called a pancreatic fistula. A pancreatic fistula occurs when fluid produced by the pancreas leaks into the abdomen after pancreas surgery. Patients who develop a pancreatic fistula can have poor short-term and long-term consequences.We are studying the effect of a medical device named HEMOPATCH on the development and seriousness of pancreatic fistulas. HEMOPATCH is a thin, flexible bovine protein-based pad that may improve tissue sealing where it is applied during surgery. Some small studies called case studies of between 2 and 7 patients, and two clinical trials have shown that HEMOPATCH is effective at stopping bleeding and reducing drain output after some types of surgery. However, there have been no completed clinical trials using HEMOPATCH to prevent or reduce pancreatic fistulas in patients having pancreas surgery, so we don't know if it works in this setting. Health Canada has approved the use of HEMOPATCH as a device to stop bleeding or seal other bodily fluids for procedures in which the control of bleeding or leakage of other body fluids or air by standard surgical techniques are either ineffective or impractical.

NCT ID: NCT03405922 Completed - Hemorrhoids Clinical Trials

Perianal Nerval Block in Proctological Interventions

Start date: February 1, 2018
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.

NCT ID: NCT03397381 Recruiting - Clinical trials for Chronic Renal Failure

Outcome of Arterio-venous Fistula for Adult Hemodialysis Patients in Assiut Governorate

Start date: January 20, 2018
Phase:
Study type: Observational

identification of the factors that affect the outcome of arteriovenous fistula in chronic renal failure patients that newly established regular dialysis in Assiut Governorate 1. To study the factors that influence the outcome of AVF 2. To evaluate the vascular complications of AVF as occlusion, rupture, aneurysmal dilation and hand ischemia

NCT ID: NCT03391687 Recruiting - Gastric Cancer Clinical Trials

Incidence of Pancreatic Fistula After Radical Gastrectomy

Start date: December 1, 2017
Phase: N/A
Study type: Observational

This study is designed to investigate the incidence of pancreatic fistula after radical gastrectomy in gastric cancer patients.

NCT ID: NCT03383562 Not yet recruiting - Infection Clinical Trials

Daytime Variation of Complication in Gastric and Pancreatic Surgery

Start date: January 1, 2018
Phase: N/A
Study type: Observational

Evaluate the daytime variation of complications in gastric and pancreatic surgery