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Falls clinical trials

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NCT ID: NCT06465602 Recruiting - Frailty Clinical Trials

Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls

NICE-FIT
Start date: May 21, 2024
Phase: Phase 2
Study type: Interventional

Falls are unplanned events resulting in contact with a lower surface. They are common in older adults, affecting one in three individuals over 65 years old. They have serious consequences, ranging from physical injuries (fractures, traumatic brain injury) to psychological repercussions. Physical training focused on muscle strength, balance, and gait has consistently been shown to prevent falls. However, there are significant challenges in its implementation, such as the need for trained personnel and long intervention times, which are associated with high costs. Therefore, developing strategies to improve the efficiency of physical training programs in older adults is mandatory. The reduced response to physical training in older adults compared to younger individuals is a well-documented phenomenon, reflecting physiological changes associated with aging. Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme for cells, mediating energy metabolism and participating in crucial processes such as DNA repair, mitochondrial function, and cell death. As we age, NAD+ levels decrease in various tissues (including the brain and muscle), contributing to the development of aging phenotypes and associated pathologies. Preclinical evidence suggests that increasing NAD+ levels reduces the appearance of aging phenotypes. During physical activity, cellular metabolic pathways that increase the demand for NAD+ to support energy production in mitochondria are activated. This increase in demand is associated with the upregulation of key enzymes involved in NAD+ degradation promoted by exercise. Considering the decrease in cellular levels of this coenzyme associated with aging, it can be hypothesized that NAD+ deficiency may play a significant role in the reduced response of older adults to training programs. Nicotinamide, a water-soluble form of vitamin B3 currently considered a nutritional supplement, is a fundamental precursor for NAD+ synthesis, capable of raising cellular levels of it. It has already been used in clinical practice in the treatment of certain endocrinological and dermatological conditions. This study aims to determine through a randomized clinical trial whether nicotinamide supplementation improves physical performance in older adults at risk of falls undergoing a physical training program.

NCT ID: NCT05889910 Active, not recruiting - Nursing Clinical Trials

Effectiveness of the Implementation of a Standardized Care Plan to Improve Fear of Falling and Incidence of Falls

FFC23
Start date: February 13, 2023
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to evaluate the effectiveness of the implementation of a standardized care plan to reduce the fear of falling in people over 65 years of age with fear of falling who live in the community. The main questions it aims to answer are: - Is it possible to reduce the fear of falling in patients over 65 years of age through an educational intervention in primary care? - Is it possible to reduce falls in patients older than 65 years through an educational intervention in primary care? Half of the participants will receive an educational intervention consisting of 6 two-hour sessions at the Health Center. The comparison group will follow the usual clinical practice recommended by the Primary Care Assistance Management of the Community of Madrid. It is intended to observe if there are differences in the fear of falling and falls in both groups.

NCT ID: NCT05615207 Recruiting - Multiple Sclerosis Clinical Trials

The Effect of Motor Imagery on Balance in Persons With Multiple Sclerosis

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

This study will investigate if the use of motor imagery to practice a balance task is as effective as physically practicing balance tasks as measured by the Berg Balance Scale (BBS) in persons with MS. A secondary purpose is to investigate if using a motor imagery balance intervention will limit fatigue typically experienced with physical movement in this population.

NCT ID: NCT05462015 Withdrawn - Physical Fitness Clinical Trials

Elastic Band Resistance Training on Physical Fitness and Risk of Falls in Elderly.

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

A lack of studies has applied elastic band resistance training exercises on hospitalized elderly, so the effect of elastic band resistance training exercises on physical fitness and risk of falls was unclear. Therefore, the purposes of this study were to investigate the effectiveness of elastic band resistance training on improving physical fitness and reducing the risk of falls in hospitalized elderly with high risk of falls. This study is an experimental study. The experimental group was given 3 times a week for 2 consecutive weeks of elastic band resistance training, while the control group was given regular rehabilitation exercises. The differences in physical fitness and fall risk between the two groups were examined.

NCT ID: NCT04993781 Recruiting - Falls Clinical Trials

Electronic Strategies for Tailored Exercise to Prevent FallS

eSTEPS
Start date: June 8, 2023
Phase: N/A
Study type: Interventional

The objectives of this proposal are to evaluate the eSTEPS CDS (eSTEPS) in a cluster randomized controlled trial. The intervention includes the following: 1) A machine learning-based fall injury risk screening algorithm to improve traditional fall risk screening. 2) Provider BPA and/or Care Gap and Smart Set to provide CDS that helps primary care providers develop a tailored fall prevention exercise plan in the context of a Medicare Wellness Visit and 3) eSTEPS Patient App and exercise tools to provide older patients continued access to their interactive, tailored exercise plan.

NCT ID: NCT04969094 Recruiting - Falls Clinical Trials

Reducing Fall Risk With NMES

NMES
Start date: January 4, 2022
Phase: N/A
Study type: Interventional

Falls are dangerous leading to injuries, hospital admissions and even death. Fall prevention is a priority but effective programs only reduce falls by 30%. Weak hip muscles may be one reasons individuals experience a loss of balance. However individuals who have weak hip muscles may be unable to exercise at sufficient intensities to improve their hip muscle strength. The purpose of this study is to utilize a common physical therapy method, neuromuscular electrical stimulation (NMES), on the hip muscles to improve hip muscle strength and improve balance. The new program focuses on using NMES during a resistance training program along with exercise to improve standing balance, walking and stepping over objects. This study will test the additive effect of NMES applied to the hip muscles during a balance and strengthening program to improve balance and mobility, and ultimately reduce the risk of falls in older Veterans at high risk for falls.

NCT ID: NCT04804579 Completed - HIV Infection Clinical Trials

Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use

Start date: October 20, 2021
Phase: N/A
Study type: Interventional

This study is being conducted to assess the acceptability and feasibility of a randomized trial of a 10 week virtual intervention to reduce fall risk in people with HIV who consume alcohol. The hypothesis is that this randomized trial of the fall prevention intervention will be found to be feasible and acceptable in this pilot stage. Standardized assessments will be administered in-person at Boston University Medical Campus to assess various domains including fall risk, fear of falling, physical performance measures (such as grip strength, balance, and gait speed), substance use, and other related measures. The intervention has 3 main components: home exercises, virtual group sessions and weekly phone check-ins. Home exercise will be customized to match the current fitness level of participants. Participants will be asked to complete assigned exercises 3 times per week. Additionally, there will be a weekly virtual group session led by an Occupational Therapist trained in group facilitation via Zoom. The virtual group sessions will be used to help answer any questions and lead a discussion around challenges related to falls. Finally, a member of the research team will check-in with participants once per week to answer any remaining questions that participants have, provide individual feedback on exercises, and set up reminders for the upcoming week. Reminders will be tailored to the individual participant's needs to remind the participant to complete the intervention's components.

NCT ID: NCT03961750 Completed - Exercise Clinical Trials

TAIC: Student-led Exercise for Older Adults at Risk of Falling

TAIC
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The National Records of Scotland population projections show the pension age population increasing by 25% over the next 25 years. Falls are a major cause of hospitalisation in older adults, one in three community dwelling older adults over 65 years of age fall each year. There is a need to explore novel methods of delivering care to a growing older adult population. A programme of exercise called OTAGO has been found to reduce the number of falls for older adults. Several studies have explored the use of students to lead exercise interventions but these have not included assessing the impact to student educational experiences and outcomes with varying degrees of success on patient outcomes and no adverse events. Research Aim: To examine the feasibility of a student-led exercise intervention in improving falls risk outcomes for community dwelling older adults at risk of falling referred from NHS falls services. Study Design: A feasibility study examining a single patient group undertaking a 12 week, student-led, OTAGO exercise class for community dwelling older adults at Glasgow Caledonian University. OTAGO consists of progressive strength and balance exercises. Participants will be screened, invited to consent to the trial, asked to undertake the 12 week intervention and assessed using physical measures before and after the trial and face to face interviews after the trial. Recruitment will be through the NHS Greater Glasgow and Clyde and Lanarkshire community falls teams and the exercise delivery is consistent with usual care, the main difference is the location and student leaders. Students are qualified OTAGO Leaders. Funding has been received from AGILE the Chartered Society of Physiotherapists professional network working with older adults. Student educational experiences and outcomes will be assessed over the study period and are included in a separate study protocol

NCT ID: NCT03958994 Completed - Dementia Clinical Trials

A Systems Approach to Falls and Discharge Planning

Start date: September 23, 2019
Phase:
Study type: Observational

The aim of this study is to generate knowledge on how to improve care for people living with dementia who are in acute hospital. The framework for data collection will be the SHEL [Software (policy) , Hardware (equipment), Environment and Liveware (people)] guidelines. This tool has been chosen for this research because Adams (2008) as well as George, Long, and Vincent (2013) argue that in order to improve care for people with dementia it is important to focus on both wider distal elements like the structural components of an organisation in addition to proximal features like the people factor. This framework will allow for interview data to be collected on the following: 1. Interactions between patient, carers and staff. 2. Hardware (equipment) used on the ward. 3. Software (paperwork/policy). 4. The hospital environment.

NCT ID: NCT03874728 Completed - Aging Clinical Trials

The Effects of Minimal Shoes in Older People at Risk of Falls: The Feetback Shoe Study

FSS
Start date: November 20, 2019
Phase:
Study type: Observational

A third of people over 65, and half of people over 80, fall at least once a year. Falls are the most common cause of death from injury in the over 65s and result in a significant financial burden on the whole society. Shoes directly influence balance, gait, and the subsequent risk of slips, trips and falls by altering somatosensory feedback to the foot and ankle. Minimal shoes, that is shoes lacking a firm heel cup, a rigid sole or longitudinal arch support, have shown advantages in strengthening muscles and improving balance as compared to conventional shoes. However, limited research has studied the effect of minimal shoe in older people at risk of falls. The aim of the project will be to assess the effects of minimal shoes in older people at risk of falls, compared to conventional shoes and barefoot.