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Embryo Transfer clinical trials

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NCT ID: NCT06372119 Not yet recruiting - Embryo Transfer Clinical Trials

Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT)

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to evaluate the effectiveness of the letrozole-stimulated cycle strategy versus the artificial cycle strategy for endometrial preparation in women with irregular menstrual cycles after one cycle of endometrial preparation. The primary question it aims to answer is: • Does the letrozole-stimulated cycle strategy for endometrial preparation result in a higher live birth rate compared to the artificial cycle strategy in women with irregular menstrual cycles after one cycle of endometrial preparation? Participants will undergo screening before endometrial preparation for frozen embryo transfer, following which they will be randomly assigned to one of two groups: LETS or AC. In the LETS group, investigators will prescribe Femara® 2.5 milligrams (Novartis, Switzerland) at a dose of 5 milligrams/day for 5 days to stimulate follicular development and Cyclogest® 400 milligrams (Actavis, UK) at a dose of 800 milligrams/day for luteal phase support. In contrast, the AC group will receive Valiera® 2 milligrams (Laboratories Recalcine, Chile) starting with a dose of 6 milligrams/day, up to a maximum dose of 12 milligrams/day) and Cyclogest® 400 milligrams (Actavis, UK) at a dose of 800 milligrams/day. Researchers will compare the LETS and AC groups to determine if there are differences in live birth rates.

NCT ID: NCT06134609 Recruiting - Embryo Transfer Clinical Trials

Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.

NCT ID: NCT06084793 Not yet recruiting - Clinical trials for Patient Satisfaction

Music for Anxiety in Embryo Transfers

MUSIC-ET
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare if playing music before and during an embryo transfer can make a difference for women who are going through a frozen embryo transfer as part of a medical procedure called assisted reproduction technology (ART). The main questions it aims to answer are: - Does listening to music before and while having the embryo transfer make patients feel more satisfied and less anxious? - Does listening to music before and during the embryo transfer affect how likely it is for the woman to get pregnant? Before the embryo transfer, the participants will listen to music through earphones or speakers. During the embryo transfer, the participants will listen to music through speakers. During the embryo transfer, the comparison group will not listen to music and will receive the usual care. The aim is to see if listening to music before and during the embryo transfer can help make the procedure better for women.

NCT ID: NCT06026553 Recruiting - Postoperative Pain Clinical Trials

Assessing Ketorolac (Toradol) at Oocyte Retrieval

Alleviate
Start date: August 10, 2022
Phase: Phase 1
Study type: Interventional

To determine if a nonsteroidal anti-inflammatory drug (NSAID), Ketorolac (Toradol), can improve pain control and decrease narcotic use after undergoing egg retrieval.

NCT ID: NCT05460416 Not yet recruiting - Embryo Transfer Clinical Trials

Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer

TePPAFET
Start date: August 22, 2022
Phase: Phase 4
Study type: Interventional

Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer

NCT ID: NCT05364528 Completed - IVF Clinical Trials

Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer

Start date: January 1, 2016
Phase:
Study type: Observational

The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques. The secondary end points include the evaluation of the difficult transfer rates.

NCT ID: NCT04725864 Recruiting - Infertility Clinical Trials

Progesterone as Luteal Support in Frozen IVF Natural Cycles

ProFET
Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

The ProFET study aims to investigate if luteal phase support by vaginal progesterone, is superior to no luteal phase support, in terms of live birth rate per woman after a frozen embryo transfer (FET), in a natural cycle (NC) after in-vitro fertilization (IVF), and if 7 weeks of treatment is superior to 3 weeks duration.

NCT ID: NCT04619524 Recruiting - IVF Clinical Trials

Biomarkers of Endometrial Receptivity

BIOMER
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Analysis of proteins from cervical mucus will be done in patients undergoing infertility treatment (fresh or frozen embryo transfer). Cervical mucus will be analysed for potential new biomarkers of endometrium receptivity. Comparison of the peptide spectrum will be done for the pregnant and not pregnant patients.

NCT ID: NCT04297553 Completed - PCOS Clinical Trials

Fresh Versus Freeze-only After CAPA IVM on PCOS Patients

Start date: March 6, 2020
Phase: N/A
Study type: Interventional

IVM (in vitro maturation) has been proved to be a more friendly treatment protocol for PCOS (polycystic ovary syndrome) patients compared with conventional controlled ovarian stimulation, with less complications (especially ovarian hyperstimulation syndrome), shorter treatment duration, lower cost, and acceptable pregnancy outcomes.

NCT ID: NCT04253470 Completed - Female Infertility Clinical Trials

Debate on Progesterone Elevation on the Day of Triggering

PE
Start date: January 1, 2012
Phase:
Study type: Observational

The association between serum progesterone (P) levels, measured on the day of ovulation trigger, and the outcome of in vitro fertilization cycles, has been one of the major controversies in the field of ovarian stimulation endocrinology. This is a single-center retrospective cohort study. Study duration period is from January 2012 to December 2016. All fresh embryo transfer (ET) both at cleavage stage and blastocyst stage, performed in Humanitas Fertility Center during the study period, were included.