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Embryo Transfer clinical trials

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NCT ID: NCT06372119 Recruiting - Embryo Transfer Clinical Trials

Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT)

Start date: April 22, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to evaluate the effectiveness of the letrozole-stimulated cycle strategy versus the artificial cycle strategy for endometrial preparation in women with irregular menstrual cycles after one cycle of endometrial preparation. The primary question it aims to answer is: • Does the letrozole-stimulated cycle strategy for endometrial preparation result in a higher live birth rate compared to the artificial cycle strategy in women with irregular menstrual cycles after one cycle of endometrial preparation? Participants will undergo screening before endometrial preparation for frozen embryo transfer, following which they will be randomly assigned to one of two groups: LETS or AC. In the LETS group, investigators will prescribe letrozole 5 milligrams/day for 5 days to stimulate follicular development and micronized progesterone 800 milligrams/day for luteal phase support. In contrast, the AC group will receive oral estradiol valerate 6-12 milligrams/day and micronized progesterone 800 milligrams/day. Researchers will compare the LETS and AC groups to determine if there are differences in live birth rates.

NCT ID: NCT06134609 Recruiting - Embryo Transfer Clinical Trials

Does Sexual Intercourse Affect the Outcomes of Frozen-thawed Embryo Transfer?

Start date: November 13, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test whether sexual intercourse the night after embryo transfer affects thawed embryo implantation rates. Women undergoing one of their first four frozen embryo transfers with a good quality embryo will be randomly assigned to two groups. The study group is subjected to have intercourse without using a condom at the evening/night after the embryo transfer, while the control group will abstain from intercourse for the next 48 hours after the transfer. Researchers will compare the ongoing pregnancy rates between the intervention group and the control group.

NCT ID: NCT06026553 Recruiting - Postoperative Pain Clinical Trials

Assessing Ketorolac (Toradol) at Oocyte Retrieval

Alleviate
Start date: August 10, 2022
Phase: Phase 1
Study type: Interventional

To determine if a nonsteroidal anti-inflammatory drug (NSAID), Ketorolac (Toradol), can improve pain control and decrease narcotic use after undergoing egg retrieval.

NCT ID: NCT04725864 Recruiting - Infertility Clinical Trials

Progesterone as Luteal Support in Frozen IVF Natural Cycles

ProFET
Start date: May 1, 2021
Phase: Phase 4
Study type: Interventional

The ProFET study aims to investigate if luteal phase support by vaginal progesterone, is superior to no luteal phase support, in terms of live birth rate per woman after a frozen embryo transfer (FET), in a natural cycle (NC) after in-vitro fertilization (IVF), and if 7 weeks of treatment is superior to 3 weeks duration.

NCT ID: NCT04619524 Recruiting - IVF Clinical Trials

Biomarkers of Endometrial Receptivity

BIOMER
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Analysis of proteins from cervical mucus will be done in patients undergoing infertility treatment (fresh or frozen embryo transfer). Cervical mucus will be analysed for potential new biomarkers of endometrium receptivity. Comparison of the peptide spectrum will be done for the pregnant and not pregnant patients.

NCT ID: NCT04124913 Recruiting - Infertility, Female Clinical Trials

Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles

Start date: January 2, 2019
Phase: Phase 4
Study type: Interventional

The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.

NCT ID: NCT03642665 Recruiting - Embryo Transfer Clinical Trials

Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer

NAFT
Start date: September 25, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates clinical pregnancy rates, obstetrical outcome parameters, costs and patient preferences in natural cycle versus artificial cycle frozen embryo transfers (FET).

NCT ID: NCT03518528 Recruiting - Infertility Clinical Trials

Comparison of Vaginal and Transdermal Oestrogen Before Frozen Thawed Embryo Transfer

Start date: August 30, 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to compare pregnancy outcomes of frozen-thawed embryo transfer after endometrial preparation with vaginal estradiol or transdermal estradiol and to evaluate women's satisfaction

NCT ID: NCT02825290 Recruiting - Embryo Transfer Clinical Trials

Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study

Start date: July 2016
Phase: Phase 4
Study type: Interventional

This study evaluates the outcomes of frozen-thawed embryo transfer (FET) success rate with modified luteal support - addition of a single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively vs. traditional luteal support with vaginal progesterone only in ovulating women.

NCT ID: NCT02650310 Recruiting - Embryo Transfer Clinical Trials

New Device to Maintain the Embryo Temperature During Transfer

EmbryoTemp
Start date: April 2015
Phase: N/A
Study type: Interventional

The embryo transfer implies transportation from the incubator where they have been at 37 ° C, to the transfer catheter inside a laminar flow hood whose working surface is also maintained at 37 ° C. . From the laboratory to the operating room the embryo is exposed to a temperature drop, and consequently thermal stress occurs, which may compromise its future viability. The aim of this study is to assess the possible improvement in the clinical results when the embryos are transported in a stable device to avoid the drop in temperature throughout the transfer process. With the use of this thermosetting device heated to 37 ° C, researchers expect a 15% increase in pregnancy rates.