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Edema clinical trials

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NCT ID: NCT05226247 Recruiting - Clinical trials for Mechanical Ventilation Complication

Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)

SystoWean
Start date: August 8, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.

NCT ID: NCT05224895 Recruiting - Ultrasonography Clinical Trials

The Effect of Trendelenburg Position on the Ultrasonographic Airway Measurements

Start date: February 15, 2022
Phase:
Study type: Observational

The aim of this study is to compare the changes in upper airway edema with the preoperative and postoperative ultrasonographic measurements of patients who undergo pobotic prostatectomy in the trendelenburg position. The secondary aim is to investigate the correlation between OSAS risk levels determined by the STOP-BANG score in the preoperative period of the patients participating in the study airway ultrasound measurements and postoperative critical respiratory events in the preoperative and postoperative period.

NCT ID: NCT05224102 Recruiting - Clinical trials for Diabetic Macular Edema

A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema

ELEVATUM
Start date: February 28, 2022
Phase: Phase 4
Study type: Interventional

This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino American, or Native American/Alaska Native/Native Hawaiian or other Pacific Islander; in addition, a cohort of Asian Indian participants will be enrolled in India.

NCT ID: NCT05223569 Recruiting - Clinical trials for Macular Edema Due to Diabetes Mellitus

Home Monitoring of Diabetic Macular Edema

Start date: March 3, 2022
Phase: N/A
Study type: Interventional

Diabetic macular edema (DME) is part of diabetic retinopathy (DR) and a leading cause of central visual loss in people with diabetes . Most patients require pharmacological inhibition using anti-vascular endothelial growth factor (VEGF) agents with multiple monitoring visits that include optical coherence tomography (OCT), visual acuity test, and multiple injections.The substantial visit frequency puts pressure on ophthalmic clinics, and can impose a tremendous burden on both patients and their caregivers. Therefore, self-service examination instruments that can be portable and fast-moving become the key for realizing tele-medicine. Recently, the investigators have developed a portable, self-administrated home OCT machine, which is designed for home-based OCT scanning and monitoring for patients with retinal diseases including DME, age related macular degeneration (AMD) and choroidal neovascularization (CNV) that require multiple anti-VEGF injections. The investigators have confirmed its image quality and validated the retinal thickness measurements obtained from this device by comparing with hospital OCT (staff-administrated and clinic-based).In this study, the investigators will conduct a randomized clinical trial (RCT) to compare the efficacy and cost-effectiveness of a home OCT monitoring model versus standard hospital care model for patients with diabetic macular edema who need anti-VEGF injections.

NCT ID: NCT05222633 Recruiting - Clinical trials for Diabetic Macular Edema

Anti-VEGF in Real-world

Start date: January 1, 2022
Phase:
Study type: Observational

Anti-vascular endothelial growth factor therapy is the major intervention for treating ischemic retina diseases. According to FDA and China Food and Drug Administration, Ranibizumab, Aflibercept, and Conbercept are major types of anti-vascular endothelial growth factor therapy drugs. In the current study, the primary aim is to observe the visual acuity, anatomy effect of anti-vascular endothelial growth factor therapy in the real-world setting.

NCT ID: NCT05217680 Recruiting - Clinical trials for Diabetic Macular Edema

Clinical Study to Evaluate PRO-169 for Diabetic Macular Edema

PRO-169
Start date: May 17, 2021
Phase: Phase 3
Study type: Interventional

Phase III clinical study to evaluate the efficacy, expressed as improvement in visual acuity in patients suffering diabetic macular edema after one year of treatment with PRO-169, compared to treatment with Lucentis® (ranibizumab).

NCT ID: NCT05217342 Recruiting - Heart Failure Clinical Trials

PVP-Guided Decongestive Therapy in HF

PERIPHERAL-HF
Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

The investigators hypothesize that a simple assessment of peripheral venous pressure (PVP) will better predict the diuretic need and long-term outcomes (all cause mortality, all cause rehospitalization, emergency department visits) compared to standard evaluation.

NCT ID: NCT05158699 Recruiting - Cataract Clinical Trials

Effectiveness of Periocular Drug Injection in CATaract Surgery

EPICAT
Start date: October 13, 2021
Phase: Phase 3
Study type: Interventional

Cystoid macular edema (CME) is a major cause of suboptimal postoperative visual acuity after cataract surgery. Topical steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs) are used to prevent CME. However, noncompliance with eye drops may compromise the effectiveness of treatment. Dropless periocular drug delivery during cataract surgery may improve the outcomes and cost-effectiveness of cataract surgery, and may alleviate the burden on homecare organizations.

NCT ID: NCT05142800 Recruiting - Breast Cancer Clinical Trials

Screening For BCRL In Targeted Therapy For Breast Cancer

Start date: December 13, 2018
Phase:
Study type: Observational

This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer. A Perometer and Sozo devise will be used to measure volume changes

NCT ID: NCT05130385 Recruiting - Glaucoma Clinical Trials

High Resolution Optical Coherence Tomography

Start date: November 30, 2021
Phase:
Study type: Observational

Comparison of high-resolution optical coherence tomography (High-Res-OCT) to conventional imaging modalities for the diagnosis of eye diseases