Clinical Trials Logo

Cataract clinical trials

View clinical trials related to Cataract.

Filter by:

NCT ID: NCT06327347 Recruiting - Cataract Clinical Trials

Comparative Study of 2 Multifocal Intraocular Lenses in Heidelberg

C2H
Start date: July 17, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the performance of 2 intraocular lenses (IOLs): ARTIS SYMBIOSE (study lenses) vs PANOPTIX (comparator) through binocular Distance Corrected Intermediate Visual Acuity (DCIVA) assessed at 80 cm in photopic conditions at minimum 1-month post-operative by a blinded evaluator. This main objective will be to show superiority of the ARTIS SYMBIOSE system on the primary endpoint. The patient population to be included is patient suffering from cataract who requires cataract surgery procedure that meet the inclusion and non-inclusion criteria and provide written informed consent. Participants will attend a total of 5 study visits: 1 preoperative visit, 1 surgery visit and 3 postoperative visits.

NCT ID: NCT06325397 Recruiting - Nuclear Cataract Clinical Trials

Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)

Start date: October 23, 2023
Phase:
Study type: Observational

To investigate the impact of high vs low Intraocular Pressure (IOP) on the intraoperative experience for the patient and surgeon. Operating at a more physiologic IOP using Active Sentry hand piece during cataract surgery will result in significantly less discomfort/pain as assessed by the decreased need for rescue medication

NCT ID: NCT06323915 Recruiting - Cataract Clinical Trials

Comparative Study of 3 Multifocal Intraocular Lenses in Murcia

C3M
Start date: April 20, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the performance of 3 intraocular lenses (IOLs): FineVision (comparator), ARTIS SYMBIOSE (study lenses), and Tecnis Synergy (comparator) through binocular distance-corrected defocus curve. This main objective will be to show superiority of the ARTIS SYMBIOSE system through binocular distance-corrected defocus curve. The patient population to be included is patient suffering from cataract who requires cataract surgery procedure that meet the inclusion and non-inclusion criteria and provide written informed consent. Participants will attend a total of 5 study visits: 1 preoperative visit, 1 surgery visit and 3 postoperative visits.

NCT ID: NCT06305338 Completed - Cataract Clinical Trials

Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling

Tilt
Start date: April 12, 2022
Phase:
Study type: Observational

During cataract surgery an artificial intraocular lens (IOL) is implanted in the eye to replace the lens and to correct the refraction for distance vision. Misalignment of IOLs can cause severe loss of visual quality. Different types of misalignment are known. Tilt, one type of IOL misalignment is thought to play a negative role for the optical performance in eyes with IOL designs, especially, if they have aspheric, toric, or multifocal optics. Various methods to measure IOL misalignments have been described. Studies assessing the IOL position have used subjective grading methods at the slit lamp examination or a Scheimpflug camera to assess IOL decentration and tilt. The subjective grading at the slitlamp may display considerable variability between examiners. This method is more qualitative than quantitative and does not allow fine resolution when reporting IOL tilt. The fact that the patient has no standardized target to focus on makes the method even less reliable. Scanning methods such as Scheimpflug photos require a very well dilated pupil exceeding 6mm to assess the IOL position. Additionally, it can be difficult to identify the anatomical structures of the eye that need to be used as points of reference. Scheimpflug camera images have been used for assessing IOL tilt previously, but erroneous results, often due to corneal magnification, have diminished their widespread use. Another possibility to assess tilt is the use of Purkinje reflexes. The light reflections of Purkinje images at ocular surfaces to evaluate ocular alignment have recently been utilized. Since light is reflected at all interfaces of media with a difference in refractive index, these reflections, called Purkinje images, can be used to assess tilt and decentration of IOLs. Two different clinically applicable Purkinjemeter system provide the measurement of IOL decentration and tilt. The main problem with Purkinje meters is accessibility, as there are only a few prototypes available worldwide. The most recently developed method for tilt quantification is the use of optical coherence tomography. This method has several advantages compared to the previous methods: OCT based devices are available in most clinics, the resolution of modern OCT devices is high, and the measurements are reproducible. Aim of this study is to measure tilt with two modern OCT based devices and one Scheimpflug camera and to predict the post-operative tilt using partial least squares regression. This method was developed by Wold and introduced to ophthalmology previously.

NCT ID: NCT06298890 Recruiting - Cataract Clinical Trials

The Pattern of Dry Eye Disease After Cataract Surgery

Start date: March 2024
Phase:
Study type: Observational

This study is designed to explore dry eye disease (DED) pattern: ocular surface, corneal morphological changes, patients' subjective assessment of DED and their correlations with ocular surface inflammation, pain biomarkers after cataract surgery according to ocular surface lubrication with artificial tears during long-term follow-up.

NCT ID: NCT06294795 Recruiting - Astigmatism Clinical Trials

Toric Intraocular Lens Implantation in Pediatric Cataract

TILIPC
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

To evaluate the visual and refractive outcomes after an intraocular lens (IOL) implantation in pediatric eyes with cataract and preexisting corneal astigmatism

NCT ID: NCT06294405 Recruiting - Lens Opacities Clinical Trials

Intraocular Lens Implant Registry Study

Start date: February 21, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this registry study is to optimize the results with intraocular lens implants used in cataract surgery.

NCT ID: NCT06277349 Completed - Cataract Clinical Trials

Multifocal-toric IOL Compared to Multifocal IOL Combined With Limbal Relaxing Incisions for Correction of Moderate Astigmatism During Cataract Surgery

Start date: March 4, 2009
Phase: N/A
Study type: Interventional

The purpose of the present study is to compare the outcome of multifocal toric intraocular lens with standard multifocal lens plus incisional surgery in patients undergoing bilateral cataract surgery.

NCT ID: NCT06266962 Completed - Cataract Clinical Trials

Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome

Start date: July 1, 2020
Phase: Phase 4
Study type: Interventional

Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in low urinary tract symptoms. There are a number of guidelines for operative technique modifications with the aim to prevent the development of IFIS. The study focuses on two options for prophylactic strategies: the application of atropine drops and the instillation of intracameral epinephrine.

NCT ID: NCT06264830 Not yet recruiting - Cataract Clinical Trials

3D Visualization System in Highly Myopic Cataract Operation

3D-HiMCO
Start date: March 2024
Phase: N/A
Study type: Interventional

This study aims to investigate the impact of depth of field differences between the use of the 3D imaging system (NGENUITY® 3D Visualization System, Alcon, TX, USA) and conventional optical microscope in cataract surgery for highly myopic patients on intraoperative parameters and outcomes.