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Diet, Healthy clinical trials

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NCT ID: NCT06449170 Active, not recruiting - Diet, Healthy Clinical Trials

Discovery of Biomarkers of Intake of of Highly Consumed Foods in Mexico

BIAMEX
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

To determine diet-health associations, researchers rely on information obtained from dietary instruments, such as the 24-hour recall (R24H), food frequency questionnaires (FFQ) and food diaries, in clinical studies. However, it is widely recognized that the information provided by the different instruments is biased by different factors including recall errors and respondent burden. The impact of the variability produced by this bias decreases the robustness of diet-health associations which results in the creation of less efficient standards and recommendations for our population. To address this, the discovery of biomarkers of food intake (BFIs) is an objective tool that indicates exposure to specific foods or various dietary patterns. BFIs allow the calibration of dietary information to obtain the real consumption of the individual and thus clarify the relationship between different pathologies of interest and the intake of different foods. BIAMEX will initially focus on the discovery of BFIs of nopal, corn tortilla, mango, avocado, guava and amaranth. For this purpose, a controlled crossover intervention study is being carried out with the 6 foods to be investigated where 24h urine and plasma samples are being collected. Subsequently, the samples collected will be analyzed by mass spectrometry.

NCT ID: NCT06122441 Active, not recruiting - Muscle Weakness Clinical Trials

RE-inventing Strategies for Healthy Ageing; Recommendations and Tools

RESTART
Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional capacity among older adults at high risk of cardiometabolic disease. The main objectives to investigate are whether a complex lifestyle intervention, compared to an active control group, will at 24 months have: 1. Produced a clinically relevant increase in cardiorespiratory fitness (primary endpoint) 2. Increased muscle strength, physical activity and reduced adiposity 3. Improved body composition, health-related quality of life and cognitive function All participants (Control and Intervention Groups) are provided with wrist-worn activity trackers at baseline and access to national recommendations on physical activity. The intervention group additionally advances through a comprehensive lifestyle program including high-intensity aerobic and strength exercise, dietary and behavioral counselling. Intervention participants are gradually transitioned into exercise activities organized by Tromsø Municipaity and local NGO:s. Testing of outcomes are performed at baseline, 6, 12 and 24 months. Primary endpoint (VO2max) is assessed at 24 months.

NCT ID: NCT05982860 Active, not recruiting - Inflammation Clinical Trials

The Effects of the MIND Diet on Oxidative Stress, Inflammation and Neurodegenerative Risk Biomarkers

Start date: June 23, 2023
Phase: N/A
Study type: Interventional

American football is a high-contact sport, also known as a collision sport. American football players are exposed to various magnitudes and frequencies of head impacts throughout the season. Accordingly, during the American football season, there is an increase in biomarkers that may be associated with brain damage and the risk of developing neurodegenerative diseases later in life. In addition, oxidative stress and inflammation can also increase in athletes during the American football season. This study was planned with the thought that the MIND diet, which is beneficial for brain health with its antioxidant and anti-inflammatory effects, may have positive effects on oxidative stress, inflammation and neurodegenerative risk biomarkers in American football players. The goal of this clinical trial is to examine the effects of the MIND diet on oxidative stress, inflammation and neurodegenerative risk biomarkers in American football players. The main question it aims to answer are: • [Question] Does the MIND diet lowers or reduce the levels of oxidative stress, inflammation and neurodegenerative risk biomarkers in American football players? Participants will be randomized into 2 groups MIND diet and control group. The current diet of the players in the control group will not be interfered with during the competition period, but the current nutrition of the players in the MIND diet group will be adapted to the MIND diet according to the food groups in the MIND diet components and their consumption frequencies. The players in the MIND diet group will be asked to include the food groups in the MIND diet in their diet in accordance with their consumption frequency. Researchers will compare the MIND diet and control groups to see if the MIND diet improves oxidative stress, inflammation and neurodegenerative risk biomarkers.

NCT ID: NCT05773833 Active, not recruiting - Blood Pressure Clinical Trials

Indigenous Supported Agriculture "Go Healthy"

ISA
Start date: February 22, 2023
Phase: N/A
Study type: Interventional

Native Americans (NAs) have limited access to healthy food and a high prevalence of diet-related diseases. This study will implement an agricultural and health education program in which NA residents of Osage Nation will receive a weekly share of healthy fresh produce coupled with healthy recipes and cooking materials. The program's effect on diet and health outcomes and it's cost-effectiveness will be evaluated, and study processes and findings will be broadly disseminated to support tribes in improving diet and health.

NCT ID: NCT05587855 Active, not recruiting - Hypertension Clinical Trials

eCulinary Medicine Emphasizing Herbs/Spices to Increase Vegetable Intake

Start date: July 30, 2021
Phase: N/A
Study type: Interventional

e-Culinary medicine emphasizes on herbs and spices, will increase consumption of vegetables and reduce sodium in the diets of people with hypertension and lead to a more favorable health profile.

NCT ID: NCT05544461 Active, not recruiting - Diet, Healthy Clinical Trials

Piloting a Web-based Personalised Nutrition App (eNutri) With UK University Students

Start date: September 20, 2022
Phase: N/A
Study type: Interventional

University students account for 50% of the UK young adult population and dietary assessment of this population is crucial in understanding the dietary changes that may occur as they transition to university and adulthood. At this time, many students will leave home for the first time and become responsible for their dietary intake through food shopping and meal preparation. The limited body of evidence in this population group suggests that starting university may be associated with weight gain and the adoption of unhealthful dietary patterns however the extent of these changes may vary based on gender, cooking ability and grocery budget, to name a few. Furthermore, dietary guidance is not typically given to university students although evidence suggests that personalised nutrition advice based on an individual's habitual dietary intake could help to provide the education and support needed for individuals to adopt a healthier diet. This student pilot study will test whether providing university students with eNutri personalised nutrition advice (intervention group) has a differential impact on diet quality in UK university students compared with those who do not receive any advice (control group) after a 4-week intervention period. 50 university students will use eNutri to record their dietary intake before being randomly allocated to the control or intervention group. After 4 weeks, both groups will repeat the eNutri food and drink questionnaire. Those in the intervention group will also be invited to complete a follow-up questionnaire after a further 8 weeks.

NCT ID: NCT05491161 Active, not recruiting - Diet, Healthy Clinical Trials

The Motility Mother-Child Cohort

MOTILITY
Start date: August 22, 2022
Phase:
Study type: Observational

The overall aim of the project is to investigate how bowel habits and nutrition in early life relate to the infant gut microbiome and metabolome from birth to 1 year of age. By unravelling links between these factors in early life, we might be able to identify new putative mechanisms by which diet via microbiota-dependent pathways affects intestinal motility in early life. Furtermore, it will be explored how the development of the gut microbiome associates with the child´s development.

NCT ID: NCT05449496 Active, not recruiting - Obesity Clinical Trials

Dietary Intervention to Improve Kidney Transplant Outcomes

Start date: June 27, 2022
Phase: N/A
Study type: Interventional

Randomized controlled trial of a curriculum intervention teaching patients to eat a whole-food plant-based dietary pattern versus standard of care in kidney transplant recipients within the first few months of transplant

NCT ID: NCT05426447 Active, not recruiting - Diet, Healthy Clinical Trials

Protein and Performance (PROPER) in Endurance Athletes

PROPER
Start date: February 23, 2021
Phase: N/A
Study type: Interventional

The present study is a parallel group design with randomised allocation to either a 1) reduced protein diet (RP) or a 2) normal protein diet (NP). The two groups will be pair-matched based on habitual dietary protein intake, endurance training, endurance performance, and sex. The aim of the study is to investigate the effects of reducing dietary protein (~1g protein/kg body mass) compared to an eucaloric normal protein diet (~2g protein/kg body mass) for 6 weeks in well-trained endurance athletes on endurance performance, body composition, skeletal muscle protein synthesis, and health-related outcomes. The hypothesis is that endurance performance will maintain or even be improved in well-trained endurance athletes after a 6-week dietary intervention of an eucaloric, protein reduced diet compared to a normal protein rich diet.

NCT ID: NCT05394779 Active, not recruiting - Obesity Clinical Trials

DEMETRA - ADVICE-002-2022

Start date: August 23, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and performance of DTXO App in improving weight loss and weight-loss maintenance in obese patients exposed to an experimental non-pharmacological treatment program. The App will include a dietary plan and customized advice program, a customized physical exercise program plan, a cognitive- behavioral assessment and support program, alerts and reminders on prescribed drugs intake and on dietary and exercise program, chat and online visits with clinical professionals, and trophies to improve patient engagement.