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Diarrhea clinical trials

View clinical trials related to Diarrhea.

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NCT ID: NCT03045926 Completed - Clinical trials for Chronic Functional Diarrhea of Unknown Origin

Chronic Administration of Diosmectite (SMECTA®) in Subjects With Chronic Diarrhoea

Start date: August 2016
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess the concentration of elemental impurities in blood and urine after chronic administration of Smecta® in subjects with chronic functional diarrhoea. For exploratory purposes, the potential effects of diosmectite on bowel microbiote composition will be investigated.

NCT ID: NCT03021434 Completed - Diarrhea Clinical Trials

Trial of Low-cost Microbiological Water Test Kits

Start date: January 2017
Phase: N/A
Study type: Interventional

The present study is a cluster randomized control trial of low-cost microbiological water test kits in rural and peri-urban communities in the Kanpur region of Uttar Pradesh, India.

NCT ID: NCT03005821 Completed - Diarrhea Clinical Trials

Chinese Pediatric Massage on Children With Acute Diarrhea: a Randomized Sham Massage Controlled Trial

Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of Chinese pediatric massage as an add-on therapy while comparing with sham massage both on the basis of usual care for 0-6 years old children with acute diarrhea.

NCT ID: NCT02959983 Completed - Clinical trials for Irritable Bowel Syndrome With Diarrhea

Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use

Start date: October 25, 2016
Phase: Phase 4
Study type: Interventional

This study will evaluate the efficacy and safety of eluxadoline 100 milligrams (mg) twice a day (BID) versus placebo for the treatment of patients with Irritable Bowel Syndrome with Diarrhea (IBS-D) who report that the use of loperamide in the prior 12 months failed to provide control of their IBS-D symptoms.

NCT ID: NCT02950142 Completed - Obesity Clinical Trials

Evidence-based Laboratory Test Order Sets in Primary Care

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.

NCT ID: NCT02949089 Completed - Diarrhea Clinical Trials

ACH04 to Assess the Safety and Tolerability in Healthy Adults Subjects

Start date: January 2013
Phase: Phase 1
Study type: Interventional

This study intends to provide information on the safety and tolerability of repeated oral doses of ACH04. A phase I, single-center, first in human, open-label, dose escalation study of ACH04 to assess the safety and tolerability in healthy adults subjects is selected to best address the study goals.

NCT ID: NCT02944617 Completed - Diarrhea Clinical Trials

Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor

Start date: November 11, 2016
Phase: N/A
Study type: Interventional

This randomized clinical trial studies how well probiotic yogurt supplement works in reducing diarrhea in patients with kidney cancer that has spread from the primary site to other places in the body (metastatic) and that are being treated with vascular endothelial growth factor-tyrosine kinase inhibitor therapy. Studying samples of blood and stool from patients who eat probiotic yogurt and those who avoid probiotic yogurt may help doctors plan better treatment.

NCT ID: NCT02934178 Completed - Diarrhea Clinical Trials

Shigella WRSS1 Vaccine Trial in Bangladesh

Start date: February 23, 2017
Phase: Phase 1
Study type: Interventional

This is a research study of an experimental (investigational) live attenuated Shigella sonnei vaccine (WRSS1) to find a dose of the vaccine that is safe, tolerable, and develops an immune response. Shigella causes bloody and watery diarrhea, and infants and children living in developing countries experience the greatest consequences of this disease.

NCT ID: NCT02928341 Completed - Diarrhea Clinical Trials

Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo

Start date: October 2016
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the impact of a large-scale urban water supply improvement intervention on cholera and other diarrhoeal diseases. The study uses a step wedge cluster randomised controlled trial (SWcRCT) to measure the effect of the intervention on cholera centre admission rates and confirmed cholera cases. A nested cohort study will examine changes in water-related practices following the intervention.

NCT ID: NCT02910219 Completed - Breast Cancer Clinical Trials

Diarrhea Prevention and Prophylaxis With Crofelemer in HER2 Positive Breast Cancer Patients

HALT-D
Start date: January 31, 2017
Phase: Phase 2
Study type: Interventional

Chemotherapy induced diarrhea is seen in up to 40-80% of patients receiving this treatment for HER2 positive locally advanced or metastatic breast cancer. This diarrhea can significantly impact a patient's quality of life and ability to tolerate chemo/anti-HER2 therapy. This study will look at the efficacy of the drug crofelemer in preventing diarrhea in breast cancer patients.