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Study to Assess Effects of Pasteurized Akkermansia Muciniphila vs Placebo in Participants With Diarrhea-predominant IBS — PAM-DIGEST  

Diarrhea-Predominant Irritable Bowel Syndrome Clinical Trial

Official title:
A Randomized, Double Blind, Placebo Controlled, Parallel Group Clinical Study to Assess Effects of Pasteurized Akkermansia Muciniphila vs. Placebo in Participants With Moderate to Severe Diarrhea-predominant Irritable Bowel Syndrome (PAM-DIGEST)

Clinical Trial Summary

The present study is a randomized, double-blind, placebo-controlled, parallel group clinical study that assesses the effect of pasteurized Akkermansia muciniphila on the complaints of subjects with moderate to severe diarrhoea-predominant irritable bowel syndrome (IBS-D). The trial is also evaluating the potential of pAkk on anxiety, low mood and stress of the participants, as well as its safety and tolerability. The intervention duration for all the study participants is 12 weeks (intervention phase). Subsequently, the participants will be invited to return to site for an end of study assessment after 21 days of no intervention (post-intervention phase).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06346847
Study type Interventional
Source A-Mansia Biotech S.A.
Contact Dr. Shalini Srivastava, MBBS, MD
Phone 9920789140
Email shalini.s@vediclifesciences.com
Status Not yet recruiting
Phase N/A
Start date May 1, 2024
Completion date May 1, 2025
View Details
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