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Depressive Disorder clinical trials

View clinical trials related to Depressive Disorder.

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NCT ID: NCT06285474 Enrolling by invitation - Depression Clinical Trials

Investigating LIFUP in Anhedonic Depression

ILIAD
Start date: October 27, 2022
Phase: N/A
Study type: Interventional

This study will observe changes in brain imaging, behavior, and symptom measures following intervention with low intensity focused ultrasound pulsation (LIFUP) targeting reward circuitry in individuals who are depressed and anhedonic.

NCT ID: NCT06281288 Enrolling by invitation - Depression Clinical Trials

Cognitive-Behavioral Therapy With Exercise Training in Adolescent Females With Elevated Depression Symptoms

Start date: December 25, 2023
Phase: N/A
Study type: Interventional

PURPOSE: To Study the Effect of Cognitive-behavioral therapy combined with exercise training in adolescent females with elevated depression symptoms BACKGROUND: Teenagers are more likely than any other age group to experience psychological issues due to depression, Adolescents have gotten active attention from society for their mental health difficulties since they are a high-level reserve talent stratum in society. Adolescent depression rates have increased in recent years, and "silent killers" are preying on them. Teenagers are more likely than any other age group to experience psychological issues due to depression, Adolescents have gotten active attention from society for their mental health difficulties since they are a high-level reserve talent stratum in society. Adolescent depression rates have increased in recent years, and "silent killers" RESEARCH QUESTION: Is there is an effect of exercise on depression in adolescent girls.

NCT ID: NCT06280170 Enrolling by invitation - Anxiety Disorders Clinical Trials

AI to Support Mental Health Case Management Providers

Start date: February 19, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the effectiveness of an artificial intelligence (AI) platform for case managers in a nonprofit health system specializing in mental health and substance use disorder. The main questions it aims to answer are: 1. Is the AI platform acceptable and feasible for case managers? 2. Does the AI platform improve providers' productivity and reported interventions? Participants will be approximately 30 case managers and their 250 adult clients receiving case management services. Researchers will compare the provider productivity and work satisfaction prior to the implementation of the AI platform to following its implementation.

NCT ID: NCT06254144 Enrolling by invitation - Clinical trials for Depressive Disorder, Major

Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking

RNT-decoding
Start date: January 10, 2024
Phase:
Study type: Observational

The purpose of this study is to decode different thinking states from the brain activation patterns and identify the neural circuits that disengage from these thinking patterns using functional magnetic resonance imaging (fMRI) measurement in individuals with major depressive disorder.

NCT ID: NCT06232291 Enrolling by invitation - Clinical trials for Major Depressive Disorder

Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant Depression

Start date: April 21, 2023
Phase:
Study type: Observational

An observational-comparative study, without interfering with the treatment, based on an operationalized interview.

NCT ID: NCT06221280 Enrolling by invitation - Postoperative Pain Clinical Trials

Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or back with the help of ultrasonography and a special block needle. Then, a patient-controlled pain device with a serum containing painkillers will be connected to your vascular access, and its use and purpose will be explained to you. You will be asked about your pain condition and the severity score of your pain, if any, at certain hourly intervals. At the end of 24 hours, a pain device will be removed, your satisfaction will be questioned and your complaints, if any, will be recorded. Immediately before surgery and 4-6 days after your surgery. An evaluation survey consisting of 10 questions will be asked to you within a 5-minute period during the weeks, at a time when you are free, and your answers will be recorded.

NCT ID: NCT06155838 Enrolling by invitation - Depression Clinical Trials

Reducing Depression and Anxiety Among Teens

Start date: November 27, 2023
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to assess the efficacy of the Early Adolescent Skills for Emotions (EASE) program, a school-based, non-specialist psychosocial intervention developed by the WHO for LMICs, in alleviating Anxiety and Depression among teens aged 13-19. The primary inquiries it seeks to address include: Does the EASE intervention effectively reduce anxiety and depression scores 12 weeks after implementation? - Can the EASE intervention enhance quality of life, improve problem-solving skills, and increase perceived emotional support? - Is the EASE intervention beneficial for enhancing the psychological well-being of parents and fostering positive parent-teen relationships?

NCT ID: NCT06145555 Enrolling by invitation - Depression Clinical Trials

Acute Psychological Sleep Stabilisation for Patients Hospitalised With Depression

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

Disturbed sleep occurs in almost all patients in psychiatric inpatient care, and although it is well known that comorbid sleep disorders in depression often persist after treatment of depression and also increase the risk of new depressive episodes, the availability of effective, evidence-based treatments for sleep disorders in hospitalised patients is very limited. The overall goal of the current project is to translate, adapt and evaluate an acute psychological sleep treatment based on cognitive behavioural therapy for insomnia (CBT-I) for patients hospitalized with depression and comorbid sleep problems in the specialized psychiatric inpatient care in the Stockholm Region. The main hypothesis for the study is that acute psychological sleep stabilization (APS) reduces self-reported sleep complains compared to care as usual reinforced with sleep hygiene advice, and secondary hypotheses are that APS also leads to reduced depressive symptoms and earlier discharge. The project includes a pilot study, which will be followed by a randomized, controlled trial of APS compared to care as usual with structured sleep hygiene (minimal active control) and treatment effect is evaluated every three days during the hospital stay and 1,2,4 and 12 weeks after randomization. APS will be performed by existing staff in the department with the support of a psychologist.

NCT ID: NCT06126198 Enrolling by invitation - Clinical trials for Major Depressive Disorder

rTMS Feasibility Study on Adolescent Depression Stimulation

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This is an open-label study, in which all participants receives an active treatment with repetitive transcranial magnetic stimulation (rTMS) according to clinical protocol. The aim with this pilotstudy is to investigate the feasibility to perform a trial of low-frequency rTMS on treatment-resistant depression in adolescents. The study includes adolescents 13-19 years old, with average to severe depression.

NCT ID: NCT06006234 Enrolling by invitation - Depression, Anxiety Clinical Trials

Analysis of Anxiety and Depression Among Elderly People

Start date: July 1, 2023
Phase:
Study type: Observational

This study is a single-center, cross-sectional, and survey study. Through questionnaire surveys, information about the anxiety and depression status of residents of elderly care institutions in Zhejiang Province is collected. Through multi-factor analysis, the relevant influencing factors that affect their psychological status are clarified. The happy old age society provides reference opinions.