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Clinical Trial Summary

The purpose of this research study is to study closed-loop transcranial alternating current stimulation (tACS) to determine its effects on symptoms of depression in people with major depressive disorder.

Clinical Trial Description

The purpose of this clinical trial is to investigate the preliminary efficacy of closed-loop tACS for the treatment of major depressive disorder (MDD) in an open-label pilot study. We will recruit 20 participants with unipolar, non-psychotic MDD. Participation will include seven visits, two of them remotely (with an in-person option as needed), and one electronic survey. Potential participants fill-in an electronic pre-screening form. If potentially eligible, a remote screening visit is performed. If eligible, participants attend five consecutive, daily stimulation sessions. Clinical assessments will be performed at baseline (Day 1 of stimulation, D1), Day five of stimulation (D5), and at their follow-up visit (14 days after the completion of stimulation) using the Hamilton Depression Rating Scale (HDRS-17). ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05772702
Study type Interventional
Source Electromedical Products International, Inc.
Contact Tobias U Schwippel, MD
Phone 817-609-4460
Status Recruiting
Phase N/A
Start date February 13, 2023
Completion date April 15, 2024

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