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Depression and Driving — D&D  

Depression Clinical Trial

Official title:
The Impact of Depression and Preclinical Alzheimer Disease on Driving Among Older Adults (Depression and Driving)

Clinical Trial Summary

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

Clinical Trial Description

The long-term goal is to accurately identify who is at risk of decline in driving, to forecast when decline will occur, and to intervene before decline, thereby reducing the numbers of crashes, injuries, and death in older adults. The findings indicate that the long preclinical stage of Alzheimer disease (AD), as reflected in amyloid imaging and cerebrospinal fluid (CSF) biomarkers among cognitively normal participants, is associated with poorer driving performance on a standardized road test. This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05446805
Study type Observational
Source Washington University School of Medicine
Contact Samantha Murphy, MA
Phone (314) 286-2435
Email msamantha@wustl.edu
Status Recruiting
Phase
Start date June 17, 2021
Completion date December 17, 2026
View Details
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