Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Other |
Plasma based biomarker |
Analyses of amyloid and tau burden among plasma samples |
Each participant will complete a blood draw within their first year of participation. |
|
Other |
Cerebrospinal fluid biomarker |
Analyses of amyloid and tau burden among cerebrospinal fluid samples |
Each participant will complete an optional lumbar puncture within their first year of participation. |
|
Other |
Amyloid PET-based biomarker |
Amyloid measured by Pittburgh compound B |
Each participant will complete a PET scan with radiotracer PIB within their first year of participation. |
|
Other |
Tau PET-based biomarker |
Tau measured by AV1451 |
Each participant will complete a PET scan with radiotracer AV1451 within their first year of participation. |
|
Primary |
Latitude via DRIVES chip |
The latitude coordinate of the location of the vehicle being driven |
Daily for up to five years |
|
Primary |
Longitude via DRIVES chip |
The Longitude coordinate of the location of the vehicle being driven |
Daily for up to five years |
|
Primary |
Vehicle Speed via DRIVES chip |
The speed at which the vehicle being driven is moving. |
Daily for up to five years |
|
Primary |
Speed Limit via DRIVES chip |
The posted speed limit for the location that participant is driving. |
Daily for up to five years |
|
Primary |
Difference via DRIVES chip |
The difference between the speed at which the vehicle is moving and the posted speed limit for the location. |
Daily for up to five years |
|
Primary |
Event Name via DRIVES Chip |
Name of the geofence in which participant had a driving event. |
Daily for up to five years |
|
Primary |
Address via DRIVES chip |
Address of the location in which participant had a driving event. |
Daily for up to five years |
|
Primary |
Event Type via DRIVES chip |
Enumeration describing the type of event: ignition on, heartbeat, ignition off, braking, acceleration, overspeeding, idling, low fuel, cornering, low battery event, diagnostic event triggered. |
Daily for up to five years |
|
Primary |
Event Time via DRIVES chip |
Timestamp in GMT on which the event occurred. |
Daily for up to five years |
|
Primary |
Odometer Reading via DRIVES chip |
Odometer reading of the vehicle. |
Daily for up to five years |
|
Primary |
Trip Distance via DRIVES chip |
Total distance covered during the trip |
Daily for up to five years |
|
Primary |
Peak Speed via DRIVES chip |
Highest speed attained by the vehicle during the trip. |
Daily for up to five years |
|
Primary |
Average Speed |
Average trip speed of the vehicle. |
Daily for up to five years |
|
Primary |
Initial Speed via DRIVES chip |
Speed at the beginning of the trip. |
Daily for up to five years |
|
Primary |
Final Speed via DRIVES chip. |
Speed at the end of the trip. |
Daily for up to five years |
|
Secondary |
Trail Making A |
This will be tested annually in a private office setting using paper and pen assessments. This will test executive function. |
Annually for up to five years |
|
Secondary |
Trail Making B |
This will be tested annually in a private office setting using paper and pen assessments. This will test executive function. |
Annually for up to five years |
|
Secondary |
Montreal Cognitive Assessment (MoCA) Total |
This will be tested annually in a private office setting using paper and pen assessments. This will screen for cognitive impairment. |
Annually for up to five years |
|
Secondary |
Category Fluency |
This will be tested annually in a private office setting using paper and pen assessments. This will test language ability. |
Annually for up to five years |
|
Secondary |
Phonemic Fluency |
This will be tested annually in a private office setting using paper and pen assessments. This will test language ability. |
Annually for up to five years |
|
Secondary |
Mini Mental Status Exam |
This will be tested annually in a private office setting using paper and pen assessments. This will screen for cognitive impairment. |
Annually for up to five years |
|
Secondary |
Clinical Dementia Rating (CDR) Sum of Boxes |
This will be tested annually in a private office setting using paper and pen assessments. This will test for cognitive impairment/dementia severity. |
Annually for up to five years |
|