Post-stroke Depression Treatment Effect on Stroke Recurrence — STROKE  

Depression Clinical Trial

Official title: Impact of Pots-stroke Depression Treatment on Stroke Recurrence

Status Completed

Clinical Trial Summary

It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.

Clinical Trial Description

A large body of evidence suggests that depression is associated with a increased risk of many chronic diseases, including hypertension, diabetes, stroke and particularly coronary heart disease. Post stroke depression (PSD) may develop as a result of vascular disease. A previous meta-analysis showed that depression significantly increased the risk of development of stroke, and this increase was probably independent of other risk factors, including hypertension and diabetes.

Clarifying this issue has important implications; if depression increases the risk of development of recurrent stroke, so treating PSD might decrease the occurrence of recurrent stroke. To our knowledge there is no study attempting to clarify the relationship between PSD treatment and stroke recurrence. To fill these gap, we systematically conducted a study to assess whether PSD is associated with recurrent stroke, cardiovascular events or death. Thus, in the current study, three different arms of follow-up of patients with first-ever stroke, were used to predict the outcome over 52 weeks. ;

Related Conditions & MeSH terms

• Cardiovascular Events
• Depression
• Depressive Disorder
• Recurrence
• Stroke
• Stroke Recurrence

• NCT number: NCT04776226
• Study type: Interventional
• Source: Ege University
• Status: Completed
• Phase: N/A
• Start date: February 11, 2017
• Completion date: March 30, 2019