Mechanism of Action of Transcranial Magnetic Stimulation

Status Active, not recruiting

Clinical Trial Summary

This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.

Clinical Trial Description

This project aims to use functional connectivity magnetic resonance imaging (fcMRI) to study patients with unipolar depression receiving TMS. Patients will be scanned before and after a full course of TMS and clinical measures for depression severity and memory will be obtained at the same times.The project has the following aims and hypothesis: (1) to determine the therapeutic antidepressant mechanism of action of TMS at the circuit level (2) to study the use of fcMRI as a state biomarker for depression (3) to study the use of fcMRI as a predictor of response for depression. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04278521
Study type	Interventional
Source	Massachusetts General Hospital
Contact
Status	Active, not recruiting
Phase	N/A
Start date	November 2011
Completion date	April 1, 2025

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