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Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

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NCT ID: NCT04115904 Enrolling by invitation - Pain, Postoperative Clinical Trials

Acute Pain Rate of Single Versus Two-visit Root Canal Treatment of Teeth With Necrotic Pulps

Acute pain
Start date: February 8, 2018
Phase: Phase 2
Study type: Interventional

Aim to compare acute pain rate after single-visit ortwo-visits treatment of teeth with necrotic pulp and apical periodontitis .90 teeth with a diagnosis of pulp necrosis and apical radiolucency at the apex.Working length was established with EAL and confirmed radiographically. Flex-R files were used to complete canal preparation. Level ofdiscomfort were recorded and cases with acute postoperative pain.

NCT ID: NCT04035330 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain

Start date: September 2019
Phase: N/A
Study type: Interventional

To compare the effect of using Etidronate in sodium hypochlorite versus sodium hypochlorite irrigating solution on: - Postoperative pain in patients with necrotic pulp. - Bacterial load reduction & main bacterial species detected preinstrumentation and post-instrumentaion - Periapical Matrix metalloproteinase 9 level (MMP-9) postinstrumentation and pre-obturation

NCT ID: NCT04035083 Not yet recruiting - Pulp Necroses Clinical Trials

Laser Activated Irrigation Versus Passive Ultrasonic Irrigation

Start date: September 2019
Phase: N/A
Study type: Interventional

assessment of bacterial reduction and post-operative pain following Laser activated irrigation using sodium hypochlorite and a 980 nm diode laser device as an adjunct to conventional root canal treatment, and comparing it with passive ultrasonic irrigation using sodium hypochlorite and an ultrasonic device in patients with single rooted asymptomatic necrotic teeth.

NCT ID: NCT04035070 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria

Start date: January 2021
Phase: Phase 4
Study type: Interventional

• The aim of this study is to compare the degree of postoperative pain and the antimicrobial effect in terms of bacterial count reduction after using co-amoxiclav-clindamycin solution versus MTAD and sodium hypochlorite irrigating solutions in patients with necrotic pulp.

NCT ID: NCT04018456 Completed - Clinical trials for Apical Periodontitis

Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation root canal treatment in mature single canal with pulp necrosis and apical periodontitis.

NCT ID: NCT04000854 Recruiting - Clinical trials for Regenerative Endodontics in Traumatized Immature Teeth

Regenerative Treatment of Traumatized Immature Permanent Incisors With Pulp Necrosis

Start date: February 19, 2019
Phase: N/A
Study type: Interventional

Endodontic management of traumatized immature permanent teeth with pulp necrosis is both a clinical challenge for the dental practitioners and a public health care problem. Even though there are feasible treatment procedures (such as apexification with calcium hydroxide and with Mineral Trioxide Aggregate (MTA), the long-term survival of these teeth is questionable because none of these techniques can provide continuation of root formation and thickening of the dentin walls. As a result, the immature tooth is weak and prone to fracture. Recently, regenerative endodontic procedures have gained much attention as biologically based treatment alternative to the techniques described above, but the scientific evidence is insufficient. These procedures aim to remove necrotic and damaged tissues and replace those with healthy functioning pulp-dentin complex. We plan to invite 120 patients to participate in this study. The inclusion criteria will be children between the ages of 7-19 years with traumatized permanent incisors with immature roots and open apices and pulp necrosis. Patients will be recruited from specialist clinics in Stockholm, Västerbotten and Norrbotten. The patients will be treated by specialists in endodontics and pediatric dentistry with regenerative endodontics. During a 5-year follow-up period the most important outcomes are continuous root development and healing of pulp necrosis. Severe traumatic dental injuries leading to severe complication that could result in early tooth loss can have a severe impact on oral health related quality of life. Therefore, regenerative endodontics can have beneficial effect treating these teeth.

NCT ID: NCT03849222 Completed - Pulp Necrosis Clinical Trials

Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth

Start date: August 20, 2013
Phase: Phase 2/Phase 3
Study type: Interventional

This study was conducted to evaluate the effect of the use of apical matrix, with Mineral Trioxide Aggregate (MTA) or calcium hydroxide Ca(OH)2 Apexification on apical healing and calcific barrier formation of immature teeth with non- vital pulp.

NCT ID: NCT03813433 Not yet recruiting - Pulp Necrosis Clinical Trials

Discoloration of Endosequence and Mineral Trioxde Aggregate in Revascularization of Necrotic Immature Permanent Teeth

Start date: June 2023
Phase: N/A
Study type: Interventional

the objective of this study is to evaluate post operative pain after using Endosequence versus Mineral Trioxide Aggregate as coronal plug material in revascularization of non vital immature anterior teeth

NCT ID: NCT03804450 Completed - Pulp Necroses Clinical Trials

Magnetic Resonance Imaging (MRI) of Pulp Regeneration

Start date: July 1, 2017
Phase: Phase 2
Study type: Interventional

The present study was conducted to test whether pulp-like tissue can be regenerated in mature teeth with closed apex? And whether the size of the apical diameter affects the success of REPs? And whether Magnetic resonance imaging (MRI) can be used to quantitatively assess the vitality of the regenerated pulp-like tissue.

NCT ID: NCT03792217 Completed - Clinical trials for Dental Pulp Necrosis

Postoperative Pain After Endodontic Irrigation Using 1.3% Versus 5.25% Sodium Hypochlorite

Start date: July 2011
Phase: N/A
Study type: Interventional

The aim of this prospective, randomized, clinical trial was to evaluate the effect of 1.3% sodium hypochlorite (NaOCl) concentration versus 5.25% NaOCl concentration on post-operative pain and medication intake in adult patients with pulp necrosis in mandibular molars.