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Deglutition Disorders clinical trials

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NCT ID: NCT05865483 Recruiting - Clinical trials for Myotonic Dystrophy 1

Profile of Dysphagia in Myotonic Dystrophy Type 1 (DM1)

SwallowDM1
Start date: July 3, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about swallowing difficulties (dysphagia) in patients living with myotonic dystrophy type 1 (DM1). The main questions it aims to answer are: - whether the size and structure of the muscles involved in swallowing differ to those without the disease - how the size and structure of muscles may associate with swallowing function and swallowing symptoms in this group. Participants will undergo a range of tests including: - Ultrasound (US) assessment of the muscles involved in swallowing - An x-ray swallowing study (known as videofluoroscopy) - Assessment of swallowing symptoms, including questionnaires - Assessments of mobility, activity and breathing - Assessments of quality of life and wellbeing

NCT ID: NCT05862792 Recruiting - Post Operative Pain Clinical Trials

Liposomal Bupivacaine and Transoral Robotic Surgery

Start date: June 1, 2023
Phase:
Study type: Observational

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.

NCT ID: NCT05862142 Not yet recruiting - Clinical trials for Deglutition Disorders

A Predictive Model for Oropharyngeal Dysphagia in Non-hospitalized Older Patients

Start date: June 6, 2023
Phase:
Study type: Observational

Oropharyngeal dysphagia (OD) is a highly prevalent and growing condition in the older population. It affects approximately one in three community-dwelling elderly, almost half of the geriatric patients, and even more than half of elderly nursing home residents. The main complications of OD are respiratory infections such as aspiration pneumonia, malnutrition, and dehydration. It supposes substantial costs for the healthcare system, increases the risk for (re)admissions and length of stay, and has an important impact on the quality of life of people who suffer from it. The aim of this study is to develop a predictive model to identify non-hospitalized older patients at risk for oropharyngeal dysphagia, quantify that risk, and facilitate decision-making according to personal, clinical, and socio-emotional characteristics.

NCT ID: NCT05861596 Recruiting - Stroke Clinical Trials

Repetitive Transcranial Magnetic Stimulation on Dysphagia in the Stroke Patient

Start date: November 23, 2022
Phase: N/A
Study type: Interventional

Participants suffered from acute stroke with dysphagia in single hospital who were determined by CT/MRI and clinical evaluation. Current project will recruit participants and randomize into two groups.One group will receive NMES, traditional swallowing therapy and rTMS therapy five times per week for 2 weeks ; Another group will receive NMES and traditional swallowing therapy with shame rTMS five times per week for 2 weeks. FEES and SSA were used for evaluated swallowing function before the therapy and after 2 weeks therapy.

NCT ID: NCT05832658 Completed - Stroke Clinical Trials

Efficacy of Game-Based EMG-Biofeedback Therapy in Post-Stroke Dysphagia

Start date: May 7, 2023
Phase: N/A
Study type: Interventional

This study aims to determine the effectiveness of game-based biofeedback application via surface electromyography in patients with post-stroke dysphagia. The same treatment interventions will be applied with and without biofeedback, and thus the contribution of adding biofeedback to the treatment will be determined.

NCT ID: NCT05828537 Not yet recruiting - Clinical trials for Pediatric Post Extubation Dysphagia

The Use of PEDI_ EAT 10 Score Versus Nurse Performed Screening in the Assessment of Post Extubation Dysphagia

Start date: September 30, 2023
Phase:
Study type: Observational

Invasive mechanical ventilation is one of the most common interventions in critically ill patients, and is invariably characteristic, if not defining, of ICU therapeutic regimen Much attention has been paid to complications occurring during and because of mechanical ventilation, such as nosocomial infections, delirium, and critical illness neuropathy and myopathy. However, an often underappreciated and minimally explored complication of mechanical ventilation is post-extubation dysphagia .

NCT ID: NCT05818501 Completed - Technology Clinical Trials

Dysphagia Cups in Elderly and Rehabilitation Setting

Start date: July 13, 2023
Phase: N/A
Study type: Interventional

The study has 6 research questions regarding the use of dysphagia cups: Primary study questions: 1. Can the use of the dysphagia cups increase water consumption and liquid consumption during the trial period? 2. Can the use of the dysphagia cups reduce the frequency and intensity of choking and coughing while drinking? 3. What are the potential risks to the service users while using the dysphagia cups? Secondary study question: 4. Can the use of the dysphagia cups enhance the autonomy of the service users in drinking? Auxiliary study questions: 5. Can the use of the dysphagia cups reduce the amount of thickener used for water consumption? 6. What are the perceived benefits and acceptability of using the dysphagia cups?

NCT ID: NCT05806710 Recruiting - Dysphagia Clinical Trials

Safety and Acceptance of GourMed© Prepackaged Nutritional Products in the Elderly Dysphagic Patient: MODiet Project

MODiet
Start date: October 12, 2022
Phase: N/A
Study type: Interventional

The aim of the MoDiet study is to evaluate the usefulness of the GourMed© prepackaged diet in guaranteeing a safe, compliant and effective diet satisfying the nutritional needs of the elderly dysphagic patient.

NCT ID: NCT05802459 Recruiting - Quality of Life Clinical Trials

Evaluation of the Functional Status of Jejunoplasty and Coloplasty and Its Impact on Quality of Life (CEREC)

CEREC
Start date: December 15, 2022
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective population-based cohort study is to assess: - The evolution of the functional status of patients undergoing complex esophageal reconstruction - Its impact on quality of life, depending on the type of conduit performed. Participants - Will be asked to complete different quality of life questionnaires during every follow-up visit - Will undergo additional tests to assess functionality

NCT ID: NCT05795569 Recruiting - Clinical trials for Deglutition Disorders

Removal of Nasogastric Feeding Tube Post Extubation in ICU : a Prospective Randomized Trial

FIRST
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

Post-extubation dysphagia (PED) is a frequent but still underestimated condition in the intensive care units (ICU). In the international literature, the manifestations and consequences of PED lead to intra- and post-intensive care comorbidities. The exact etiology of PED is unknown, but considered multifactorial. Numerous causes, acquired during ICU, can lead to a delay in the reintroduction of intravenous nutrition, or even favor the development of inhalation pneumopathy. One of these causes is the presence of the nasogastric tube. The incidence of ECD varies from 3 to 62%. Its presence impacts morbidity and mortality. Preventive strategies for PED have only been studied with questionable methodologies. The goal of ICU therapists is to detect PED as early as possible in order to implement curative strategies such as adapted nutrition and early swallowing rehabilitation.