Covid19 Clinical Trial
Official title:
Effectiveness of Telemedicine Use in Home Management of Adult Egyptian Mild COVID-19 Cases
Keeping in mind the rising number of cases in Egypt and the strain they put on hospital
infrastructure, the idea of home isolation and follow up for COVID 19 positive cases has been
adopted in many countries and was approved by World Health Organization (WHO) and Egyptian
Ministry of health (MOH).
Telehealth can help to mitigate this risk by minimizing the amount of face-to-face
interactions. The WHO mentioned telemedicine among essential services in "strengthening the
Health Systems Response to COVID-19" policy. The aim in this study is to study the
effectiveness of telemedicine in managing mild COVID cases regarding isolation measures,
symptoms, medications adherence, and reporting of red flags and side effects.
Objectives:
- To assess the effectiveness of follow up of mild COVID-19 cases in home isolation
- To assess the applicability of telemedicine tools in the follow up of those patients and
early identification of warning symptoms needing more intensive management measures.
- To assess the clinical characteristics for mild COVID-19 cases and post covid sequelae
and the course of symptoms
- To assess the persistence of symptoms during follow up.
- To assess the quality of life during home management period.
- To assess cost-effectivenes of home isolation vs hospital admission in mild COVID-19
cases.
Study population & Sample size :
The study includes 400 Adult (18-65 years) Egyptian patients with mild COVID 19 diagnosed by
PCR consented (oral consent) to home isolation to follow them.
Study Design:
Prospective observational study.
Methods:
• All patients will be subjected to thorough history and clinical examination. 400 adult mild
COVID cases consented to home isolation to follow them by: phone calls, what's app, hot line
for emergency, Triage sheet, zoom meetings.
Patients will be given brochures about home isolation (by Egyptian MOH), list of medications,
plan of follow up.
1. Daily follow up for: fever chart, report any new symptoms or progression of previously
present symptom or presence of red flags.
2. Blood samples will be obtained and CT chest will be done according to the usual
protocol.
3. Patients will be followed for 3 months to detect post covid sequelae and the course of
symptoms (and the persistence of any symptoms).
4. Questionnaire will be done to assess the patients' commitment to the advices and
regulations of home isolation as well as forms to assess fatigue and the quality of life
(36-Item Short Form Survey; SF-36).
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05047692 -
Safety and Immunogenicity Study of AdCLD-CoV19-1: A COVID-19 Preventive Vaccine in Healthy Volunteers
|
Phase 1 | |
| Recruiting |
NCT04395768 -
International ALLIANCE Study of Therapies to Prevent Progression of COVID-19
|
Phase 2 | |
| Completed |
NCT04508777 -
COVID SAFE: COVID-19 Screening Assessment for Exposure
|
||
| Completed |
NCT04506268 -
COVID-19 SAFE Enrollment
|
N/A | |
| Terminated |
NCT04555096 -
A Trial of GC4419 in Patients With Critical Illness Due to COVID-19
|
Phase 2 | |
| Completed |
NCT04961541 -
Evaluation of the Safety and Immunogenicity of Influenza and COVID-19 Combination Vaccine
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT04546737 -
Study of Morphological, Spectral and Metabolic Manifestations of Neurological Complications in Covid-19 Patients
|
N/A | |
| Not yet recruiting |
NCT04543006 -
Persistence of Neutralizing Antibodies 6 and 12 Months After a Covid-19
|
N/A | |
| Completed |
NCT04494646 -
BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)
|
Phase 2 | |
| Completed |
NCT04532294 -
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Neutralizing Antibody in Healthy Participants
|
Phase 1 | |
| Terminated |
NCT04581915 -
PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19
|
Phase 2/Phase 3 | |
| Terminated |
NCT04542993 -
Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy
|
Phase 2 | |
| Completed |
NCT04507867 -
Effect of a NSS to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III
|
N/A | |
| Not yet recruiting |
NCT04527211 -
Effectiveness and Safety of Ivermectin for the Prevention of Covid-19 Infection in Colombian Health Personnel
|
Phase 3 | |
| Completed |
NCT04387292 -
Ocular Sequelae of Patients Hospitalized for Respiratory Failure During the COVID-19 Epidemic
|
N/A | |
| Completed |
NCT04537663 -
Prevention Of Respiratory Tract Infection And Covid-19 Through BCG Vaccination In Vulnerable Older Adults
|
Phase 4 | |
| Not yet recruiting |
NCT05038449 -
Study to Evaluate the Efficacy and Safety of Colchicine Tablets in Patients With COVID-19
|
N/A | |
| Completed |
NCT04979858 -
Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
|
N/A | |
| Completed |
NCT04610502 -
Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 Serum in COVID-19 Patients
|
Phase 2 | |
| Active, not recruiting |
NCT06042855 -
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)
|
Phase 3 |