COVID-19 Clinical Trial
Official title:
Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease: Diagnostic/Prognostic Utility in South Asian Populations
Determining whether in the mouth there are differences between the participant groups in the nature and activity of mucosal innate immunity, in immune responses to SARS-COV2 antigens, or in the oral microbiome
Cross sectional with longitudinal component - Stimulated whole mouth fluid (SWMF) and blood samples from South Asian and non-Asian populations - Controls, and COVID-19 patients in both populations. - Oral disease questionnaire and clinical examination - Separation of SWMF into pellet for DNA extraction for microbiomics and supernatant for cell phenotype analysis, cytokines and antibodies to SARS-CoV2 antigens ;
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