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Clinical Trial Summary

Determining whether in the mouth there are differences between the participant groups in the nature and activity of mucosal innate immunity, in immune responses to SARS-COV2 antigens, or in the oral microbiome


Clinical Trial Description

Cross sectional with longitudinal component - Stimulated whole mouth fluid (SWMF) and blood samples from South Asian and non-Asian populations - Controls, and COVID-19 patients in both populations. - Oral disease questionnaire and clinical examination - Separation of SWMF into pellet for DNA extraction for microbiomics and supernatant for cell phenotype analysis, cytokines and antibodies to SARS-CoV2 antigens ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05212766
Study type Observational
Source King's College London
Contact Stephen J Challacombe, PhD
Phone 02971887188
Email stephen.challacombe@kcl.ac.uk
Status Recruiting
Phase
Start date April 7, 2022
Completion date December 30, 2024

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