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NCT ID: NCT06402188 Recruiting - Colorectal Cancer Clinical Trials

ColoSeal™ ICD System Safety and Feasibility Study

Start date: June 5, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical investigation is to evaluate the safety and feasibility of the ColoSeal ICD System in a prospective, multicenter, single-arm study. The ColoSeal ICD System is intended to be used to protect a damaged segment of colon such as a surgical anastomosis, anastomosis leak, or perforation from contact with fecal flow for up to 21 days. The device will be evaluated in adult patients with rectal and rectosigmoid cancer undergoing a resection with a colorectal anastomosis.

NCT ID: NCT06317129 Recruiting - Obesity Clinical Trials

Clinical Feasibility Study of the BariTon™ System in Obese Patients

Start date: January 18, 2024
Phase: N/A
Study type: Interventional

Safety evaluation of BariaTek Medical gastric restriction and biliodigestive diversion device.

NCT ID: NCT06316154 Recruiting - Clinical trials for Echinococcosis, Hepatic

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

PAFCLE
Start date: October 22, 2023
Phase:
Study type: Observational

The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

NCT ID: NCT06267859 Recruiting - Clinical trials for Congenital Heart Defects

Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children

Start date: November 8, 2023
Phase: Early Phase 1
Study type: Interventional

The goal of the clinical study is to clarify the course of common congenital, infectious, and non-infectious diseases in children living in Uzbekistan, and to develop methods for their treatment and rehabilitation. The main questions it aims to answer: - Analysis of common congenital diseases among children; - Analysis of commonly diagnosed bronchopulmonary and cardiovascular diseases among children; - Based on the results of the primary research, common diseases among children will be identified; - Analysis of existing treatment methods and their effectiveness; - Development of modern methods of treatment and rehabilitation of children.

NCT ID: NCT06169592 Recruiting - Liver Cirrhosis Clinical Trials

Verification of Risk Factors of Thrombohemorrhagic Complications in Recipients After Related Liver Transplantation

VORTAL
Start date: April 22, 2022
Phase:
Study type: Observational

The aim of the study is to improve the results of related transplantation of the right liver lobe by verifying the general predictors of the development of hemostatic system disorders and optimizing a comprehensive program for thrombohemorrhagic complications preventing.

NCT ID: NCT06150872 Recruiting - Clinical trials for Coronary Artery Disease

Photochemical Tissue Passivation Treatment of Saphenous Vein Grafts in CABG

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

Early feasibility study of the DurVena Photochemical Tissue Passivation (PTP) device for treatment of saphenous vein grafts in participants undergoing elective coronary artery bypass graft (CABG) surgery. Study to be conducted outside the U.S.

NCT ID: NCT05783544 Recruiting - Clinical trials for COPD Exacerbation Acute

Impact of A. Lumbricoides on Pulmonary Aspergillosis Development

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

The prevalence of ascariasis in COPD patients with and without concomitant pulmonary aspergillosis and in controls will be determined. To assess the influence of ascaridosis on the development of pulmonary aspergillosis in COPD patients cytokine status of patients will be studied.

NCT ID: NCT05616754 Recruiting - COVID-19 Clinical Trials

A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell)

Start date: November 7, 2022
Phase: Phase 3
Study type: Interventional

The study was designed as a randomized, blind and controlled trial. A total of 300 patients aged 18 and above who were immunized with recombinant novel coronavirus protein vaccine (CHO cell) for more than 4 months (60 patients aged 60 and above) were randomly and blind divided into the experimental group and the control group, and received the experimental vaccine and the control vaccine, respectively. In addition, 100 patients over 4 months after the completion of basic immunization with COVID-19 mRNA vaccine were selected as the open observation group, all of whom received 1 dose of experimental vaccine.

NCT ID: NCT04611412 Recruiting - Metabolic Syndrome Clinical Trials

Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism

Start date: December 15, 2020
Phase:
Study type: Observational

to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism

NCT ID: NCT04599621 Recruiting - Clinical trials for Coronary Heart Disease

Unstable Angina Pectoris in Comorbidity With Anxiety-depressive Syndrome

Start date: November 5, 2018
Phase:
Study type: Observational

Introduction: Today it is necessary to emphasize that coronary heart disease is often associated with anxiety disorders. Research over the years has shown several and sometimes surprising links between coronary heart disease and mental illness, and has even suggested that both of these phenomena may actually cause each other. However, the exact nature of these links has not yet been clearly established. Methods: The study included 202 patients with coronary artery disease, of whom 42 patients were with stable angina pectoris, they participated as a control group, and 160 patients with unstable angina pectoris, who made up the main group. Among them there are 102 women and 100 men between the ages of 30 and 88. The average age was 63.75 ± 11.37 years. All study participants had blood in the morning on fasting after 8-12 hours of fasting from the cubital vein. Determination of the level of cytokines TNF-α, IL-1β, IL-4 and IL-10 in blood serum by enzyme-linked immunosorbent assay (ELISA). All participants in the study had blood drawn in the morning on fasting after 8-12 hours of fasting from the cubital vein. The level of uric acid was determined on the CYAN Start apparatus using a unified method. When examining patients with unstable angina pectoris were used: hospital anxiety and depression scale [Kozlova S.N. 2013]. And also the Spielberger-Khanin scale [Psychiatry - Hoffman A.G. 2010], developed by Spielberger Ch.D. and adapted by Yu.L. Khanin. to assess cognitive functions [Psychiatry - Gofman A.G. 2010].