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NCT ID: NCT05311111 Recruiting - Clinical trials for Coronary Artery Disease

Efficacy and Safety of the Distal Radial Approach

TunDRA
Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The aim of this non-inferiority trial is to determine if the distal radial access (DRA) during percutaneous coronary intervention (PCI) has an acceptable efficacy compared to the reference access through the conventional radial artery (TRA) with a lower rate of radial artery occlusion (RAO) in real life practice.

NCT ID: NCT05298098 Recruiting - Clinical trials for Acute Decompensated Heart Failure

Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure

HSS
Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Acute decompensated heart failure (HF) is one of the most common cardiologic issues in emergency departments. Loop diuretics have long been recognized as the key for the treatment of Acute Decompensated Heart Failure (ADHF).However, chronic treatment with diuretics may limit their response and deteriorates the renal function. The hypertonic saline solution (HSS) has been proposed in recent years as an adjunctive therapy for intravenous loop diuretics to improve or restore their initial pharmacological efficacy. In this study the investigators will evaluate the effectiveness of HSS as an adjunct to i.v. furosemide in patients admitted for AHF with renal dysfunction

NCT ID: NCT05297110 Recruiting - Hypertension Clinical Trials

Olive Leaf Extracts in the Control of Cardiovascular Risk

Atherolive
Start date: August 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This study will be carried out in 2 emergency departments (at the exit of the emergency room) and 2 external consultations (endocrinology of the CHU FB Monastir and diabetology consultation, Jemmal hospital). Patients over 18 years of age with: 1. Arterial hypertension (hypertension). 2. Or diabetes. 3. Or one or more other cardiovascular risk factors (AHA, ESC) or risk of cardiovascular disease> 20% according to the Framingham scale (apart from hypertension and diabetes were included.

NCT ID: NCT05289232 Completed - Clinical trials for Suture, Complication

Prevalence and Complications of Suture in the ED

Start date: January 2, 2020
Phase:
Study type: Observational

included patients who had sutured wounds in the ED were asked about complications after suture .

NCT ID: NCT05287633 Recruiting - Dyspepsia Clinical Trials

Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting

Start date: March 20, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. The investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during Ramadan compared to placebo.

NCT ID: NCT05269004 Active, not recruiting - Multiple Sclerosis Clinical Trials

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis

OLERO
Start date: May 3, 2022
Phase: Phase 3
Study type: Interventional

This is a Phase IIIb, single-arm, multicenter, OLE study. Participants receiving ocrelizumab as an investigational medicinal product (IMP) in a Roche sponsored Parent study who continue to receive ocrelizumab or are in safety follow-up at the time of the closure of their respective Parent study (WA21092, WA21093 or WA25046) are eligible for enrollment in this extension study. Participants who will continue ocrelizumab treatment will receive IMP based on the dosage and administration received at the time of rollover from the Parent study.

NCT ID: NCT05264753 Recruiting - Clinical trials for Patent Ductus Arteriosus

PMCF Study to Evaluate Efficacy, Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects

Start date: December 20, 2021
Phase:
Study type: Observational [Patient Registry]

This is a retrospective and prospective, multi-center, international, post marketing follow-up study to evaluate the safety and efficacy of the Occlutech PDA by using Occlutech Occlusions-Pusher (OOP) in patients with patent ductus arteriosus defects. Efficacy and safety of implanted device(s) will be evaluated by vital signs, ECGs, and echocardiography data on baseline/implantation visit (include assessments within 36 hrs. post-procedure), Day 30 to Day 90, 6 months to 1 year, 2 years to 3 years after implantation.

NCT ID: NCT05258838 Recruiting - Psoriasis Clinical Trials

Tunisian National Registry on Psoriasis

PsoTReg
Start date: July 12, 2022
Phase:
Study type: Observational

National cross-sectional multicentric study to describe the epidemiological characteristics of patients with Psoriasis in Tunisia

NCT ID: NCT05244343 Completed - COVID-19 Clinical Trials

I VACCIN Hospitalization of COVID-19 Patients

Start date: January 25, 2022
Phase:
Study type: Observational

A REALLIFE evaluation of rate of hospitalized patients in Intensive Care Units and in medical Units of non -vaccinated patients vs vaccinated patients

NCT ID: NCT05229965 Completed - Clinical trials for Acute Pain Due to Trauma

Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies

Start date: November 1, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to: Compare the effect of paracetamol alone against Paracetamol+Codeine association against the association of paracetamol + Cafeine in the treatment of post-traumatic acute pain of the limbs.