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NCT ID: NCT06192901 Completed - Senile Cataract Clinical Trials

Safety and Performance of Hydrophobic and Hydrophilic Intraocular Lenses After Bilateral Cataract Surgery

Start date: September 18, 2023
Phase:
Study type: Observational

Subjects who had a bilateral age-related cataract surgery with the IOLs AT ELANA 841P and AT LISA tri 839MP will be contacted and invited to attend a postoperative visit more than one year after the surgery

NCT ID: NCT05617820 Completed - Dyspareunia Clinical Trials

Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal Atrophy

Start date: November 15, 2022
Phase: Phase 3
Study type: Interventional

Randomized, double-blind, placebo-controlled, parallel-designed, multiple-site, bioequivalence study with clinical endpoints.

NCT ID: NCT05511948 Completed - Hyperpigmentation Clinical Trials

Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and Lentigos

Start date: August 18, 2022
Phase: Phase 2
Study type: Interventional

This is a randomized, observer-blinded, vehicle-controlled multi-dose trial that examines the effect of twice daily application of 0.8% DBI-102 Gel, 4% Hydroquinone cream, and Vehicle Gel for 12 weeks in adults with Fitzpatrick Skin Types IV-V and a colorimeter L* measurement between 57.8 and 46.1.

NCT ID: NCT05309135 Completed - Corneal Edema Clinical Trials

A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction

Escalon
Start date: March 24, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety of a fixed dose of human corneal endothelial cells when administered with varying concentrations of Rho kinase inhibitor (Y-27632) in patients with corneal edema secondary to endothelial dysfunction.

NCT ID: NCT04937920 Completed - Tinea Versicolor Clinical Trials

A Trial to Evaluate the Safety and Antimicrobial Efficacy of DBI-002 Probiotic in Adults With Tinea Versicolor

Start date: March 16, 2021
Phase: Phase 2
Study type: Interventional

A Randomized, Double-Blinded, Aqueous Gel-Controlled Dose Escalating Trial to Study the Safety and Antimicrobial Efficacy of DBI-002 Probiotic vs. Aqueous Gel and Vehicle Gel vs. Aqueous Gel in Adults with Tinea Versicolor (DBI-202).

NCT ID: NCT04936087 Completed - Wheelchair Users Clinical Trials

Effects of the WHO 8-step Wheelchair Service Delivery Process on Wheelchair Users in El Salvador: a Cohort Study

WUV
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

The objective of this study was to test the hypotheses that wheelchair-related health, wheelchair skills, wheelchair use, poverty probability, and quality of life would improve; and that the number of wheelchair repairs required, adverse events, caregiver burden and the level of assistance provided would decrease after the delivery of manual wheelchairs following the World Health Organization (WHO) 8-step service-delivery process. This was a longitudinal, within-subject study design including 247 manual wheelchair users in El Salvador. The intervention consisted of the WHO 8-step process as well as maintenance reminders. Outcome assessments on wheelchair-related health, wheelchair skills, wheelchair repairs required, adverse events, caregiver burden and the level of assistance, poverty probability, and quality of life were performed via structured interviews at the initial assessment, at wheelchair delivery, and at 3- and 6-month follow-up. Wheelchair use was measured with dataloggers at assessment, delivery and 3-month follow-up.

NCT ID: NCT04711213 Completed - Clinical trials for Cataract in Inflammatory Ocular Disorders

A Clinical Study to Assess the Efficacy and Safety of SED80 for Use in Cataract Surgery

Start date: September 14, 2020
Phase: Phase 2
Study type: Interventional

Patients at least 40 years of age who are undergoing cataract surgery will be randomized to receive treatment with one of four groups of dexamethasone ophthalmic suspension or placebo eye drops to determine if the drops decrease inflammation and pain inside the eye and are safe after cataract surgery.

NCT ID: NCT04332640 Completed - Cataract Clinical Trials

Clinical Evaluation of the Next Generation Phaco System

ALPINE
Start date: September 28, 2020
Phase: N/A
Study type: Interventional

This study is a prospective, open-label clinical study of the VERITAS Vision System. The study will be conducted at up to three sites, with minimum 55 eyes and up to 150 eyes to be treated. The investigator or designee will perform the cataract surgery with the VERITAS Vision System on the subjects. The data from the system log files, the questionnaire, the operative report and other medical records will be used to assess the clinical utilization of the VERITAS Vision System.

NCT ID: NCT04330001 Completed - Presbyopia Clinical Trials

Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).

NCT ID: NCT04143919 Completed - Heart Failure Clinical Trials

Heart Failure IDentification in a High Risk Cardiovascular OutpatiEnt Population (HIDE)

HIDE
Start date: January 31, 2020
Phase: N/A
Study type: Interventional

This is a pilot, multicenter, real-world, single-visit, low risk, phase IV interventional study to efficiently identify new cases of heart failure (HF) Stage C in subjects who are at risk of cardiovascular (CV) disease in high-volume ambulatory primary care settings in 3 countries in Central America.