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NCT ID: NCT05431699 Not yet recruiting - Clinical trials for Human Papilloma Virus

Single Visit Clinical Validation of AmpFire, a Low-cost HPV Test

SCALE
Start date: August 2022
Phase:
Study type: Observational

The purpose of this study is to validate a new low-cost, self-collected HPV screening test (AmpFire) and compare it to the standard provider collected careHPV, for the detection of high grade cervical cancer.

NCT ID: NCT05309135 Active, not recruiting - Corneal Edema Clinical Trials

A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction

Escalon
Start date: March 24, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety of a fixed dose of human corneal endothelial cells when administered with varying concentrations of Rho kinase inhibitor (Y-27632) in patients with corneal edema secondary to endothelial dysfunction.

NCT ID: NCT05295641 Recruiting - Heart Failure Clinical Trials

American Registry of Ambulatory or Acute Decompensated Heart Failure

AMERICCAASS
Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to better characterize and understand the population of patients with ambulatory or acutely decompensated heart failure in the American continent, getting to know their sociodemographic, clinical and paraclinical characteristics

NCT ID: NCT05201027 Enrolling by invitation - Cataract Senile Clinical Trials

Study to Optimize the IOL Constant of a New Multifocal Intraocular Lens

HECATE A
Start date: January 28, 2022
Phase: N/A
Study type: Interventional

Prospective, non-comparative, multicenter study on medical device with 6 months follow-up.

NCT ID: NCT05136144 Recruiting - Clinical trials for Seborrheic Keratosis

Adaptive Design Study for Safety and Efficacy of Treatment Regimens With SM-020 in Subjects With Seborrheic Keratosis

Start date: October 19, 2021
Phase: Phase 2
Study type: Interventional

This is a first-in-humans adaptive design open label trial to explore the safety and efficacy of SM-020. Multiple dosing cohorts will be enrolled. The first cohort will have a two-week treatment period of twice daily applications followed by a four-week follow-up period. Based on the results at any time from the first and subsequent cohorts, additional cohorts will explore different dosing regimens.

NCT ID: NCT05090787 Not yet recruiting - Cataract Clinical Trials

Clinical Investigation of the TECNIS 1-Piece Intraocular Lens

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

This study is a 6-month, prospective, comparative, multicenter, bilateral, parallel group, randomized (2:1), subject/evaluator masked clinical investigation of the investigational mDCB00 IOL as compared to the DCB00 IOL. The study will be conducted at up to 8 sites in countries where both the investigational and control lenses are approved for market and/or for evaluation in a clinical study and will include a total of up to 200 subjects. Subjects will be randomly assigned to receive either the test lens or the control lens in both eyes.

NCT ID: NCT04937920 Completed - Tinea Versicolor Clinical Trials

A Trial to Evaluate the Safety and Antimicrobial Efficacy of DBI-002 Probiotic in Adults With Tinea Versicolor

Start date: March 16, 2021
Phase: Phase 2
Study type: Interventional

A Randomized, Double-Blinded, Aqueous Gel-Controlled Dose Escalating Trial to Study the Safety and Antimicrobial Efficacy of DBI-002 Probiotic vs. Aqueous Gel and Vehicle Gel vs. Aqueous Gel in Adults with Tinea Versicolor (DBI-202).

NCT ID: NCT04936087 Completed - Wheelchair Users Clinical Trials

Effects of the WHO 8-step Wheelchair Service Delivery Process on Wheelchair Users in El Salvador: a Cohort Study

WUV
Start date: January 8, 2019
Phase: N/A
Study type: Interventional

The objective of this study was to test the hypotheses that wheelchair-related health, wheelchair skills, wheelchair use, poverty probability, and quality of life would improve; and that the number of wheelchair repairs required, adverse events, caregiver burden and the level of assistance provided would decrease after the delivery of manual wheelchairs following the World Health Organization (WHO) 8-step service-delivery process. This was a longitudinal, within-subject study design including 247 manual wheelchair users in El Salvador. The intervention consisted of the WHO 8-step process as well as maintenance reminders. Outcome assessments on wheelchair-related health, wheelchair skills, wheelchair repairs required, adverse events, caregiver burden and the level of assistance, poverty probability, and quality of life were performed via structured interviews at the initial assessment, at wheelchair delivery, and at 3- and 6-month follow-up. Wheelchair use was measured with dataloggers at assessment, delivery and 3-month follow-up.

NCT ID: NCT04711213 Completed - Clinical trials for Cataract in Inflammatory Ocular Disorders

A Clinical Study to Assess the Efficacy and Safety of SED80 for Use in Cataract Surgery

Start date: September 14, 2020
Phase: Phase 2
Study type: Interventional

Patients at least 40 years of age who are undergoing cataract surgery will be randomized to receive treatment with one of four groups of dexamethasone ophthalmic suspension or placebo eye drops to determine if the drops decrease inflammation and pain inside the eye and are safe after cataract surgery.

NCT ID: NCT04684485 Recruiting - Dermatitis, Atopic Clinical Trials

To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis

Start date: July 30, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase II, randomized, double-blind, placebo-controlled study in subjects with moderate to severe atopic dermatitis.